Protein Alignment msl-1 and msl1a

DIOPT Version :9

• Sequence 1: NP_001286054.1
• Gene: msl-1 / 35121
• FlyBaseID: FBgn0005617
• Length: 1039
• Species: Drosophila melanogaster
• Sequence 2: NP_001107940.1
• Gene: msl1a / 100000715
• ZFINID: ZDB-GENE-030131-8168
• Length: 489
• Species: Danio rerio
• Alignment Length: 488
• Identity: 112/488 - (22%)
• Similarity: 179/488 - (36%)
• Gaps: 137/488 - (28%)

  Fly   606 VIANHQSTKTQTDPVKTQRLQVKIRQYEMHPDMRTGSSAPSDIRKQKNVDP---VSTPETK---- 663
            :|..||         ...:.::..|:....||..:....     ..||.:|   :..|.||
Zfish    52 IIQKHQ---------VQSKAKISCRKVLSCPDQSSAGGL-----GHKNWEPSGALILPSTKQMGA 102

  Fly   664 ---TIKSKS---------------MLVNDKKTTSETSQ--------SPDQE-------------- 688
               .:||:|               |:.||.....|..|        ||:..
Zfish   103 EGSPVKSRSLFCQTNHNHLVNMDPMVSNDNNQQREGEQVGAMVGDSSPEDSPSGKHWNVRKGSGL 167

  Fly   689 IDVET--VRRKLAEHLKKELLSQS----HSSQVTLKKIR----------ERVATNLIYPPPSAPV 737
            :|.:|  :|:.|.  |:.||:.|.    |:....::.::          ||:...|........|
Zfish   168 VDPQTSCIRQILL--LQLELIEQQQKHLHNKNKEIEDLKAEKEMLMARIERMEHRLQMVKKDGVV 230

  Fly   738 SSTTITPAPTPSTTPTPGSTPQHAVTSSMDQEISAAKSKSKAAEQIATPLTPQSNSSVSSTTSTI 802
            |        .||.| |....|:...|:|.|.:.|..:        :.||...|....|..:..
Zfish   231 S--------RPSQT-TCHKEPEAETTTSDDVQHSGGR--------VQTPKQTQRGRGVKGSKG-- 276

  Fly   803 RKTLNNCSPHTYSKATARSGKLQSRFRTATFPYSTRTWEDQEFHCDNEFFLEEADELLAD----- 862
             |.|...||      |.||.:.|.|....:...|....||.:.|.....:|...:..|:.
Zfish   277 -KFLLQDSP------TGRSRRGQPRSPPTSQQESPALKEDMQCHSKEVPYLTTTEMYLSHWQTPP 334

  Fly   863 ----NPS------LEIPKWRDVPVPPSSDKIDT---ELLSDATFERRHQKYVKDEVDRKCRDARY 914
                :||      :|:|.||:..:.|...|..:   |.|.|:.|.:||.|...||..||..|.:.
Zfish   335 SPQRDPSTVHENTVEVPSWRESILEPLGQKEASDILECLDDSVFLKRHSKLELDEKRRKRWDIQR 399

  Fly   915 MKEQIRLEQLRMRRNQDEVLVALDPLRASTFYPLPEDIEAIQFVNEVTVQAFGENVVNMEARDDF 979
            ::||...::|:.|.|:.:|:...:| ...:|:..|||:|.|.....:.|.|||..:.|:: :.||
Zfish   400 IREQRMFQRLQQRMNRRKVIQESEP-ELLSFHAEPEDVEYIMVTPFLPVVAFGSPLPNLK-QQDF 462

  Fly   980 GVPWVDAIEAPTSIARSKALAEPVATLASKKIP 1012
            .:||:|        .||:...|    :..|:.|
Zfish   463 DLPWLD--------ERSRCQPE----VTKKRTP 483

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
msl-1	NP_001286054.1	PEHE	867..983	CDD:291924	38/118 (32%)
msl1a	NP_001107940.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	126..164		7/37 (19%)
		MSL1_dimer	168..203	CDD:293406	9/36 (25%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	224..311		27/112 (24%)
		PEHE	349..466	CDD:291924	38/118 (32%)
		Bipartite nuclear localization signal. /evidence=ECO:0000250|UniProtKB:Q6PDM1	380..394		6/13 (46%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170578064
Domainoid	1	1.000	61	1.000	Domainoid score	I10457
eggNOG	1	0.900	-	-		E1_2CMD8
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		oto40682
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR21656
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.930