Protein Alignment tos and RAD27

DIOPT Version :10

• Sequence 1: NP_477145.1
• Gene: tos / 35119
• FlyBaseID: FBgn0015553
• Length: 732
• Species: Drosophila melanogaster
• Sequence 2: NP_012809.1
• Gene: RAD27 / 853747
• SGDID: S000001596
• Length: 382
• Species: Saccharomyces cerevisiae
• Alignment Length: 416
• Identity: 101/416 - (24%)
• Similarity: 167/416 - (40%)
• Gaps: 93/416 - (22%)

  Fly     1 MGITGLIPFVGK-ASSQLHLKDIR---GSTVAVDTYCWLHKGVFGCAEK------LARGEDTDVY 55
            |||.||...:.: ..|.:...||:   |..||:|....|::.:....::      ...||.|...
Yeast     1 MGIKGLNAIISEHVPSAIRKSDIKSFFGRKVAIDASMSLYQFLIAVRQQDGGQLTNEAGETTSHL 65

  Fly    56 IQYCLKYVNMLLSYDIKPILVFDGQ--HLPAKALTEK--RRRDSRKQSKERAAELLRLGRIEEAR 116
            :....:.:.| :...|||..||||:  .|.:..||::  ||.::.|:..|...||       |..
Yeast    66 MGMFYRTLRM-IDNGIKPCYVFDGKPPDLKSHELTKRSSRRVETEKKLAEATTEL-------EKM 122

  Fly   117 SHMRRCVDVT---HDMALRLIRECRSRNVDCIVAPYEADAQMAWLNRADVAQYIITEDSD----- 173
            ...||.|.|:   ::.|.:|:   ....:..|:||.||:||.|.|.:........:||.|
Yeast   123 KQERRLVKVSKEHNEEAQKLL---GLMGIPYIIAPTEAEAQCAELAKKGKVYAAASEDMDTLCYR 184

  Fly   174 -------LTLFGAK-----NIIFKLDLNGSGLLVEAEKLHLAMGCTEEKYHFDKFRRMCILSGCD 226
                   ||...||     .|..:|.|.|..|.:|                  :|..:||:.|||
Yeast   185 TPFLLRHLTFSEAKKEPIHEIDTELVLRGLDLTIE------------------QFVDLCIMLGCD 231

  Fly   227 YLDSLPGIGLAKACKFILKT-----------EQEDMRIALKKIPS---YLNMRNLEVDDDYIENF 277
            |.:|:.|:|...|.| ::||           |..:......|||.   |...|.|.:|.:.|:.
Yeast   232 YCESIRGVGPVTALK-LIKTHGSIEKIVEFIESGESNNTKWKIPEDWPYKQARMLFLDPEVIDG- 294

  Fly   278 MKAEATFRHMFIYNPLERR--MQRLCALEDYETDERYCSNAGTLLEDSEQALHLALGNLNPF--S 338
              .|...:    ::|.:.:  ::.||..:.: ::||..|....|.:..:..:.   |.|:.|  .
Yeast   295 --NEINLK----WSPPKEKELIEYLCDDKKF-SEERVKSGISRLKKGLKSGIQ---GRLDGFFQV 349

  Fly   339 MKRLDSWTPEKAWPTPKNVKRSKHKS 364
            :.:........|....:|.|.:|:|:
Yeast   350 VPKTKEQLAAAAKRAQENKKLNKNKN 375

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tos	NP_477145.1	PIN_EXO1	1..202	CDD:350207	62/234 (26%)
		H3TH_EXO1	214..291	CDD:188628	24/90 (27%)
RAD27	NP_012809.1	PIN_SF	1..364	CDD:475124	97/403 (24%)