DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment tos and AT1G29630

DIOPT Version :9

Sequence 1:	NP_477145.1	Gene:	tos / 35119	FlyBaseID:	FBgn0015553	Length:	732	Species:	Drosophila melanogaster
Sequence 2:	NP_001077624.1	Gene:	AT1G29630 / 839840	AraportID:	AT1G29630	Length:	735	Species:	Arabidopsis thaliana

Alignment Length:	825	Identity:	228/825 - (27%)
Similarity:	327/825 - (39%)	Gaps:	207/825 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MGITGLIPFVGKASSQLHLKDIRGSTVAVDTYCWLHKGVFGCAEKLARGEDTDVYIQYCLKYVNM 65
            |||.||:|.:......:|:|::.|..||||||.|||||...|:.:|.:|..|..:||||:..||:
plant     1 MGIQGLLPLLKSIMVPIHIKELEGCIVAVDTYSWLHKGALSCSRELCKGLPTKRHIQYCMHRVNL 65

  Fly    66 LLSYDIKPILVFDGQHLPAKALTEKRRRDSRKQSKERAAELLRLGRIEEARSHMRRCVDVTHDMA 130
            |..:.:|||:||||..||.|...|.:|..|||::..||.|....|....|.....:.||::..:|
plant    66 LRHHGVKPIMVFDGGPLPMKLEQENKRARSRKENLARALEHEANGNSSAAYECYSKAVDISPSIA 130

  Fly   131 LRLIRECRSRNVDCIVAPYEADAQMAWLNRADVAQYIITEDSDLTLFGAKNIIFKLDLNGSGLLV 195
            ..||:..|..|||.:|||||||||||:|........||||||||..||...||||:|..|.|:..
plant   131 HELIQVLRQENVDYVVAPYEADAQMAFLAITKQVDAIITEDSDLIPFGCLRIIFKMDKFGHGVEF 195

  Fly   196 EAEKLHLAMGCTEEKYHFDKFRRMCILSGCDYLDSLPGIGLAKACKFILKTEQEDMRIALKKIPS 260
            :|.||......:...:.......||||||||||.||||:||.:|...|.|.:..|      ::..
plant   196 QASKLPKNKDLSLSGFSSQMLLEMCILSGCDYLQSLPGMGLKRAHALITKFKSYD------RVIK 254

  Fly   261 YLNMRNLEVDDDYIENFMKAEATFRHMFIYNPLERRMQRLCALEDYETDERYCSNAGTLLEDS-- 323
            :|....:.|...|.|:|.:|..||:|..:|:|....:..||.:.|         |.|   |||
plant   255 HLKYSTVSVPPLYEESFKRALLTFKHQRVYDPNAEDIIHLCDISD---------NLG---EDSDF 307

  Fly   324 -------EQALHLALGNLNPFSMKRLDSWTPEKAWPTPKNVKRSKHKSIWQTNFQSENTHTPKKE 381
                   :.|..:|||.|:||:                            |..||:|:. |||
plant   308 VGPSMPQDIAKGIALGQLDPFT----------------------------QLPFQAESV-TPK-- 341

  Fly   382 NPCALFFKKVDFVGKTLN---EEIEANQRLEQAKQTEAELFNMYSFKAKR-----RRSP------ 432
                   ..||.:.:..:   |.::....|...|....:.|...|.:|||     |.||
plant   342 -------LAVDDISRPKSFKPETVKKKLDLPVQKNLLTKYFCFASVEAKRKFKAPRISPMSLTPT 399

  Fly   433 SREDSVDQERTPP----------PSPVHKSRHNPFAKERTGEEANQRSPVVCENASLLRLLSPKK 487
            ....|:..:.||.          .|||:....||...|                      ::.|:
plant   400 DESPSIPDDNTPDLDALSSQTTNESPVYSLGENPCVSE----------------------VAEKR 442

  Fly   488 ASPLDG----------------EAGVKKVDSLKRSIFAKEQVQIRSRFFATQDEQTRL------- 529
            .||.|.                |....|.||||        |.:||::|..:.|...|
plant   443 DSPDDDAVERNHKDLHHKYCEREVDRPKSDSLK--------VIVRSKYFKQKQEDKSLKQSIPCL 499

  Fly   530 -------QREHLRDTENDDMDEQKLSSHSG--------HKKLRLVCKD-----IPGKNPIRQR-- 572
                   ||:.::...|.....::..||..        |.::....:|     ....|.:.:|
plant   500 NDCSVIGQRKAVKTVINMSSASKREESHRAIATSPCLHHDRIYNDHEDAKEASFSAMNEVAERTI 564

  Fly   573 ----CSSQISDGETDTDTTASSLLESQDKGVP----------------SPLESQEDLNNSQPQIP 617
                .:.||::.|.:......|...:.:..:|                ..|:|.|:|:..
plant   565 NTHKINHQINEEEQNPSVEIPSAFSTPENVIPLSSIAIDSCHGVATGKRKLDSDENLHKE----- 624

  Fly   618 TEGNTNSTTIRIKSLDLLLENSPEPTQESD----RNNNDAIILLSDDSCSSDQRASSTSSSSQQR 678
               |..|..:|:...|..| |:..|.:..|    .:|...|...|:.:..|.:|..|..||.:
plant   625 ---NLKSKHMRMDETDTAL-NAETPLETDDVEKFGSNISHIGHYSEIAEKSVERFVSAISSFK-- 683

  Fly   679 QNFLPTSKRRVGLSKP------STAKKGTPKSRTNGKLGAVSQNQ 717
              :..|..|..||..|      :...||........|.|..|.|:
plant   684 --YSGTGSRASGLRAPLKDIRNTCPSKGLSLKPDISKFGYASSNR 726

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tos	NP_477145.1	PIN_EXO1	1..204	CDD:189027	92/202 (46%)
tos	NP_477145.1	H3TH_EXO1	214..291	CDD:188628	29/76 (38%)
AT1G29630	NP_001077624.1	fen_arch	1..296	CDD:274717	124/300 (41%)
		PIN_EXO1	1..206	CDD:189027	92/204 (45%)
		H3TH_EXO1	214..285	CDD:188628	29/76 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	101	1.000	Domainoid score	I2341
eggNOG	1	0.900	-	-		E1_COG0258
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	228	1.000	Inparanoid score	I1150
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D796591at2759
OrthoFinder	1	1.000	-	-		FOG0003113
OrthoInspector	1	1.000	-	-		otm3071
orthoMCL	1	0.900	-	-		OOG6_101671
Panther	1	1.100	-	-	LDO	PTHR11081
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2084
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	10	9.870