Protein Alignment tos and exo1

DIOPT Version :10

• Sequence 1: NP_477145.1
• Gene: tos / 35119
• FlyBaseID: FBgn0015553
• Length: 732
• Species: Drosophila melanogaster
• Sequence 2: XP_073783256.1
• Gene: exo1 / 406778
• ZFINID: ZDB-GENE-040426-2828
• Length: 845
• Species: Danio rerio
• Alignment Length: 822
• Identity: 278/822 - (33%)
• Similarity: 387/822 - (47%)
• Gaps: 175/822 - (21%)

  Fly     1 MGITGLIPFVGKASSQLHLKDIRGSTVAVDTYCWLHKGVFGCAEKLARGEDTDVYIQYCLKYVNM 65
            |||.||:.|:..||..:|:|..||.|||||||||||||.|.||||||:||.||.|:.||:|:|:|
Zfish    40 MGIQGLLQFIKDASEPMHVKKYRGQTVAVDTYCWLHKGAFSCAEKLAKGEPTDQYVSYCMKFVDM 104

  Fly    66 LLSYDIKPILVFDGQHLPAKALTEKRRRDSRKQSKERAAELLRLGRIEEARSHMRRCVDVTHDMA 130
            |||:.:||||||||::||:|...||.||:.|:.:.::..:|||.|:|.|||....|.|::|..||
Zfish   105 LLSFGVKPILVFDGRNLPSKQEVEKSRRERRQANLQKGKQLLREGKITEARECFTRSVNITPSMA 169

  Fly   131 LRLIRECRSRNVDCIVAPYEADAQMAWLNRADVAQYIITEDSDLTLFGAKNIIFKLDLNGSGLLV 195
            ..:||..|:|.|||:|||||||||:|:||::|:||.:|||||||..||.|.:|.|:|..|:||
Zfish   170 HDVIRAARTRGVDCVVAPYEADAQLAFLNKSDIAQAVITEDSDLLAFGCKKVILKMDKQGNGL-- 232

  Fly   196 EAEKLHL----AMG--CTEEKYHFDKFRRMCILSGCDYLDSLPGIGLAKACKFILKTEQEDMRIA 254
            |.|:.||    ::|  .|||     |||.||||||||||.||.||||.||||.:......|:...
Zfish   233 EIEQCHLGRCKSLGNIFTEE-----KFRYMCILSGCDYLQSLYGIGLGKACKLLRMANNPDILKV 292

  Fly   255 LKKIPSYLNMRNLEVDDDYIENFMKAEATFRHMFIYNPLERRMQRLCALEDYETDERYCSNAGTL 319
            :||:..||.| ::.|.::|||.|.||..||.:..:::||.|::..|....|: .:....|.|||.
Zfish   293 IKKMGQYLKM-DISVPEEYIEGFTKANNTFLYQLVFDPLRRKVVPLNPYPDH-INPAALSYAGTN 355

  Fly   320 LEDSEQALHLALGNLNPFSMKRLDSWTPEKAWPTPKNVKRSK------------HKSIWQTNFQ- 371
            :.| |:.|.:|||||:..:|:|:|.:.|:.....|....||.            ..|||..|::
Zfish   356 VGD-EKGLQMALGNLDINTMQRIDDFNPDAPQTQPPKAPRSSSWNDRCDKTATTQASIWSQNYEP 419

  Fly   372 ----SENTHTPKKENPCALFFKKVDFVGKTLNEEIEANQRLEQAKQTEAELFNMYSFKAKRRR-- 430
                .::..:||:..|..         ||   |.|.:.|.| :..|.|:::        ||.|
Zfish   420 GCTKPQSPTSPKRPPPTR---------GK---ERIVSVQSL-KLPQRESQV--------KRPRED 463

  Fly   431 -SPSREDSVDQ------ERTPPPSPVHK--SRHNPFAKE-RTGEEANQRSPVVCEN--ASLLRLL 483
             |.|.:|.::|      ...|...|..|  :..|..:|| ..|..:....|   .|  |:||:..
Zfish   464 TSLSVDDLLEQYTAGVKRHCPETQPTTKPLTNDNMVSKENHCGSTSGPSRP---RNRFATLLQWR 525

  Fly   484 SPKKASPLDGEAGVKKVDSLKRSIFAKEQVQIRSRFFATQDEQ--TRLQREHLRDTENDDMDEQK 546
            :                    ||....|:....||||. .||.  ...|.:..:|:......::|
Zfish   526 N--------------------RSEEGTEEQGTCSRFFC-HDESNIAETQEDSKQDSSQSVESQEK 569

  Fly   547 LSSHSGHKKLRLVC--------KDIPGKNPIRQRCSSQIS---------DGETD----------T 584
            ..|.||.....| |        ||.|...|....|||:.:         .|.|.          .
Zfish   570 HVSQSGGDTSSL-CEEPEREQDKDEPSSPPASPSCSSRPASVGLGVFSWSGTTKELNKSVSHPAR 633

  Fly   585 DTTASSLLESQDKGV-----------------------PSPLESQEDLNNSQPQIPTEGNTNSTT 626
            |:|......|...|:                       .||:|..||..||....|::.:...:
Zfish   634 DSTERQRSSSTPSGLSTLQQFHRNKARISWAGPGLSLSSSPVEGSEDAGNSPGSPPSQDSAYFS- 697

  Fly   627 IRIKSLDLLLENSPEPTQESDRNNNDAIILLSDDSCSSDQRAS--STSSSSQQRQNFLPTSKRR- 688
             :..|:...:|||               ::..|:|....:|.|  |.|.||.......|...|.
Zfish   698 -QSSSISASVENS---------------LVTEDNSDKEKERDSDVSNSPSSSPLDRLKPAVNRTK 746

  Fly   689 -VGLSKPSTAKKGTPKSRTNGKLGAVSQNQTKLSMFGFQTKP 729
             .|||     :||.......||:    :........|.:.||
Zfish   747 VSGLS-----RKGACGQGKGGKI----ETSAPARASGLRRKP 779

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tos	NP_477145.1	PIN_EXO1	1..202	CDD:350207	114/200 (57%)
		H3TH_EXO1	214..291	CDD:188628	38/76 (50%)
exo1	XP_073783256.1	None