Protein Alignment tos and mus201

DIOPT Version :10

• Sequence 1: NP_477145.1
• Gene: tos / 35119
• FlyBaseID: FBgn0015553
• Length: 732
• Species: Drosophila melanogaster
• Sequence 2: NP_001027230.1
• Gene: mus201 / 3772069
• FlyBaseID: FBgn0002887
• Length: 1236
• Species: Drosophila melanogaster
• Alignment Length: 862
• Identity: 169/862 - (19%)
• Similarity: 308/862 - (35%)
• Gaps: 233/862 - (27%)

  Fly     1 MGITGLIPFVGKASSQLHLKDIRGSTVAVDTYCWLHKGVFGCAEK----LARGEDTDVYIQYCLK 61
            ||:|||...:......:.::.:.|..:|||...|||:.|.|..:.    |:......::.:.|
  Fly     1 MGVTGLWKLIEPCGKPVPVETLEGKILAVDISIWLHQVVKGFQDNKGSALSNAHLLGLFHRLC-- 63

  Fly    62 YVNMLLSYDIKPILVFDGQHLPAKALTEKRRRDSR-KQSKE--RAAELLRLGRIEEARSHMRRCV 123
               .||.|.::|:.:|||.....|..|..||:..| |.|.|  |...||.....:|
  Fly    64 ---KLLYYRVRPVFIFDGCVPQLKRDTIARRQQQRNKLSNEADRIQALLLQSLAKE--------- 116

  Fly   124 DVTHDMALRLIRECRSRNVDCIV-APYEADAQMAWLNRADVAQYIITEDSDLTLFGAKNIIFKL- 186
                    :::::...:|.:.:: :|         :.|...|:.  .::.||         |||
  Fly   117 --------KVVQQALGKNAELLLKSP---------VKRPPPAKK--NDEDDL---------FKLP 153

  Fly   187 DLNGSGLLVEAEKLHLAMGCTEEKYHFDK-FRRMCILSGCDYLD-------SLPGIGLAKACKFI 243
            :|..:.:....::.......:.....||: ..|....|....:|       :||.....:....|
  Fly   154 ELPAASVQDNQDESEQDTSASASDSSFDESTARHSYNSSLQAIDVKSQHFRNLPADVRHEILTDI 218

  Fly   244 LKTEQEDMRIALKKIPSYLNMRNLEVDDDYIENFMKAEATFRHMFIYNPLERRMQRL-------C 301
            .:|.::.....|.::|:.        .||:....||  ...:...:...||:..|.:       .
  Fly   219 KETRKQSSWGRLHELPAR--------SDDFCSFQMK--RLLKRRAVQESLEQAEQEMGGHTLTYA 273

  Fly   302 ALEDYETDE--------RYCSNAGTLLEDSEQALHLALGNLNPFSMKRLDSWTPEKAWPTPKNVK 358
            .|.|:..:|        ..|:..   :...|....|.:.:|...:|:           .|.:.||
  Fly   274 ELCDFFNEEGILTPTAIEQCTRQ---ISSDEHTRFLLVRDLKKKAME-----------STKQEVK 324

  Fly   359 RSKHKSIWQTNFQSENTHTPKKENPCALFFKKVDFVGKTLNEEI--EANQRLEQAKQTEAELFNM 421
            ....:.:.......:.:.:.|||     ..|.|| :|...:|::  ..:..:|:.|..:.:.:..
  Fly   325 MEMIEEVPAEEEDEKPSTSTKKE-----AVKSVD-LGTEFDEDLAKALSMSMEETKVYDEKDYEY 383

  Fly   422 YSFKAKR-RRSPSREDSVDQERTPPPSPVHKSRHNPFAKERTGE--EANQRSPVVCENASLLRLL 483
            .|.:..| .|:.:::   .:.....|:..:...:.....|..|.  ||.|.:    :..||.:||
  Fly   384 DSDQELRLNRAQTKQ---LRHAAKGPARAYMIEYGGMNDEEVGNIMEATQFN----DTQSLEKLL 441

  Fly   484 SPKKASPLD-GEAGVKKVDSLKRSIFAKEQVQIRSRFFATQDEQTRLQREHLR--DTEND-DMDE 544
            ..... |.| .:..:::...:.::|  :|..|:..   |.::.:..|..:.:.  ||:.| |::|
  Fly   442 EITTV-PTDMADNSIEEAKLISQAI--EESKQLSQ---AIEESKKNLNEDKVEIVDTDTDSDLEE 500

  Fly   545 ----QKLSSHSGHKKLRLVCKDIPGK----------------NPIRQRCSSQISDGETDTDTTAS 589
                |:|.  .|.|.|. :|.||.|:                |.|.:..|.:..|...:...:..
  Fly   501 VMEVQELD--KGKKNLE-ICVDITGQADSNDLFADIFEDGEANKIEKTISVEEDDDFIEVKDSEE 562

  Fly   590 SLLESQDKGVP----SPLESQE---------DLNNSQPQIPTEGN-----------TNSTTIRIK 630
            ..|:::|:..|    |..||.|         ::.:||..:|.|.|           ....|..:|
  Fly   563 LKLDTEDENKPITNKSIKESNEVKPFIDEIIEVKDSQEAVPAEPNLKPDLESILNDLKKQTAAVK 627

  Fly   631 SLDLLL--ENSPEPTQESDR----------------------NNNDAIILLSDDS---------- 661
            .:.|.:  |..|:|..|...                      :|:..|||.|||.
  Fly   628 DIQLNVNEEEKPKPKVEISSILDELKVKMADVKNITLDNVKLSNSVPIILSSDDESTLKSSKIVP 692

  Fly   662 -------CSSDQRASS------TSSSSQQRQNFLPTS---KRRVGLSKPST-AKKGTPKS----- 704
                   |.||...::      |.|.::..::|..||   ||....|:.|. ...||||:
  Fly   693 KQELIELCDSDDNKNNRLSPNKTPSKNKSIKDFFETSYVVKRTPDKSQASNETSPGTPKTPKPFF 757

  Fly   705 --RT--NGKLGAVSQNQ 717
              ||  :|:..|...|:
  Fly   758 RKRTPKSGRKRASDANE 774

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tos	NP_477145.1	PIN_EXO1	1..202	CDD:350207	45/209 (22%)
		H3TH_EXO1	214..291	CDD:188628	14/84 (17%)
mus201	NP_001027230.1	rad2	1..1122	CDD:273166	169/862 (20%)