Protein Alignment tos and xpg-1

DIOPT Version :9

• Sequence 1: NP_477145.1
• Gene: tos / 35119
• FlyBaseID: FBgn0015553
• Length: 732
• Species: Drosophila melanogaster
• Sequence 2: NP_491891.2
• Gene: xpg-1 / 186441
• WormBaseID: WBGene00019004
• Length: 820
• Species: Caenorhabditis elegans
• Alignment Length: 703
• Identity: 131/703 - (18%)
• Similarity: 251/703 - (35%)
• Gaps: 234/703 - (33%)

  Fly     1 MGITGLIPFVGKASSQLHLKDIRGSTVAVDTYCWLHKGVFGCAEKLARGEDTDV-YIQYCLKYVN 64
            ||||||...|...::::.|:.:.|..:|:|...|:::.      :||...|... :::..:..::
 Worm     1 MGITGLWKIVEPTATEIPLECLEGKKLAIDVSIWIYQA------QLAYPSDQPFPHLRLLVNRLS 59

  Fly    65 MLLSYDIKPILVFDGQHLPAKALTEKRRRDSRKQSKERAAELL----RLGRIEEARSHMRRCVDV 125
            .||.|.|:|:.||||..:|.   .:::..::|:|.::...::|    ::|:::|..|      ..
 Worm    60 KLLFYKIRPVFVFDGPQVPP---LKRQVLEARRQKRQNDDDILKNSKKMGKLKEIAS------GG 115

  Fly   126 THDMALRLIRECRSRNVDCIVAPYEADAQMAWLNRADVAQYIITEDSDLTLFGAKNIIFKLDLNG 190
            ..|:||                             |:..:.:|:....:.|    |.|:| |:..
 Worm   116 LDDVAL-----------------------------ANAIKEVISPSKKVIL----NDIYK-DIPS 146

  Fly   191 SGLLVEAEKLH----LAMGCTEEKYHFDKFRRMCILSGCDYLDSLPGIGLAKACKFILKTEQEDM 251
            :...::....|    |..|..|:             |..|..|.:           |:.|.:|:
 Worm   147 TSTYLDKPSAHQNDQLVYGNIED-------------SDSDDSDII-----------IVPTVKEE- 186

  Fly   252 RIALK------KIPSYLN----MRNLEVDDDYIENFMKAEATFRHMFIYNPLERRMQRLCALEDY 306
            ||:.:      :|.|.:.    |||..:..|.|....|:.:.|           :||||.
 Worm   187 RISKQFTSRKLEIQSLVEKREIMRNSRLRPDMIPQDSKSFSNF-----------QMQRLL----- 235

  Fly   307 ETDERYCSNAGTLLEDSEQALHLALGNLNPFSMKRLDSWTPEKAWPTPKNVKRSKHKSIWQTNFQ 371
                    ..|.|..:.||.......:...:|..:::...|:   .|...:|.:....|.:...:
 Worm   236 --------RRGRLNAEIEQLAKSTTTSTGGYSSDKINVTGPD---GTSHILKYAHSDEIQEVRPE 289

  Fly   372 SENTHTPKKENPCA--LFFKKVDFVGKTLNEEIEANQRLEQAKQTEAELFNMYSFKAKRRRSPSR 434
            .:.......:.|.:  |.|..|::.||.|:.|:..:.                          .|
 Worm   290 LKRDIDSLYQEPLSMTLDFFNVEYGGKKLSREVTPDD--------------------------VR 328

  Fly   435 EDSVD--QERTPPPSPVHKSRHNPFAKERTGEEANQRSPVVCENASLLRLLSPKKASPLDGEAGV 497
            |:.||  :||.             ..|:..|.::         .:.:|..::.|:   :....|.
 Worm   329 EEIVDRLEERL-------------IDKKERGYQS---------KSGMLEAIARKR---IRQHYGT 368

  Fly   498 KKVDSLKRSIFAKEQVQIRSRFFATQDEQTRLQREHLRDTENDDMDEQKLSSHSGHKKLRLVCKD 562
            :.|:..|.....|::.:|........|::..|| |.|.:|....:| ::::|...||
 Worm   369 ETVEDKKEEEKRKKEQRIEDDMIEVSDDEMVLQ-EVLLETAAKSLD-KRMASLEKHK-------- 423

  Fly   563 IPGKNPIRQRCSSQISDGETDTD---------TTASSLLE---------SQDKGVPSPLESQEDL 609
            :|.:            |.|.:.|         ::|.:|:|         ..||......:.||.|
 Worm   424 VPSE------------DEEIEWDPQRYDKPSTSSAPALMEDYIHLNYSDEDDKTPELYRDLQEFL 476

  Fly   610 NNSQ-PQIPTEGNTNSTTIRIKSLDLLLENSPEPTQESDRNNNDAIILLSDDS 661
            .|:. |.|.:.|...:..:.::.|.|:                |.::  ||||
 Worm   477 TNAGIPWIESPGEAEAQCVELERLGLV----------------DGVV--SDDS 511

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tos	NP_477145.1	PIN_EXO1	1..204	CDD:189027	43/211 (20%)
		H3TH_EXO1	214..291	CDD:188628	17/86 (20%)
xpg-1	NP_491891.2	PIN_SF	1..>111	CDD:301351	29/118 (25%)
		PIN_SF	<449..548	CDD:301351	18/81 (22%)
		H3TH_XPG-like	554..>586	CDD:188620

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0258
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810