Protein Alignment tos and crn-1

DIOPT Version :10

• Sequence 1: NP_477145.1
• Gene: tos / 35119
• FlyBaseID: FBgn0015553
• Length: 732
• Species: Drosophila melanogaster
• Sequence 2: NP_491168.1
• Gene: crn-1 / 171917
• WormBaseID: WBGene00000794
• Length: 382
• Species: Caenorhabditis elegans
• Alignment Length: 395
• Identity: 96/395 - (24%)
• Similarity: 172/395 - (43%)
• Gaps: 57/395 - (14%)

  Fly     1 MGITGLIPFVG-KASSQLHLKDIR---GSTVAVDTYCWLHKGVFGCAE--KLARGED--TDVYIQ 57
            |||.||...:. .|.|.:.:.:::   |.|||:|....|::.:....:  ...:.||  |..::.
 Worm     1 MGIKGLSQVIADNAPSAIKVNEMKAFFGRTVAIDASMCLYQFLIAVRQDGSQLQSEDGETTSHLM 65

  Fly    58 YCLKYVNMLLSYDIKPILVFDGQHLPAKALTEKRRRDSRKQSKERAAELLRLGRIEEARSHMRRC 122
            ..|.....:....:||:.||||:....|....::|.:.|.::::...|....|.::||....||.
 Worm    66 GMLNRTVRMFENGVKPVYVFDGKPPDMKGGELEKRSERRAEAEKALTEAKEKGDVKEAEKFERRL 130

  Fly   123 VDVT---HDMALRLIRECRSRNVDCIVAPYEADAQMAWLNRADVAQYIITEDSDLTLFGAKNIIF 184
            |.||   :|.|.||:   ....:..:.||.||:||.|.|.:|......:|||.|...||: .::.
 Worm   131 VKVTKQQNDEAKRLL---GLMGIPVVEAPCEAEAQCAHLVKAGKVFGTVTEDMDALTFGS-TVLL 191

  Fly   185 KLDLNGSGLLVEAEKLHLAMGCTEEKYHFDKFRRMCILSGCDYLDSLPGIGLAKACKFILKTEQE 249
            :..|......:..::.:|::...|.|...::|..:|||.||||..::.|:|..||.:.|  .:.:
 Worm   192 RHFLAPVAKKIPIKEFNLSLALEEMKLSVEEFIDLCILLGCDYCGTIRGVGPKKAVELI--RQHK 254

  Fly   250 DMRIALKKIPS----------YLNMRNLEVDDDYIENFMKAEATFRHMFIYNPLERRMQRLCALE 304
            ::...|:.|..          |...|.|.::.: :....:.|.|::..    .:|..:|.||..:
 Worm   255 NIETILENIDQNKYPPPEDWPYKRARELFLNPE-VTKPEEVELTWKEA----DVEGVIQFLCGEK 314

  Fly   305 DYETDERYCSNAGTLLEDSEQALHLALGNLNPFSMKRLDSW-------------TPEKAWPTPKN 356
            ::  :|....||...|:.|.::          .:..|:||:             |..||....|.
 Worm   315 NF--NEERIRNALAKLKTSRKS----------GTQGRIDSFFGNSTKVTCVTAATKRKAEEAEKA 367

  Fly   357 VKRSK 361
            .|.:|
 Worm   368 KKGAK 372

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tos	NP_477145.1	PIN_EXO1	1..202	CDD:350207	55/211 (26%)
		H3TH_EXO1	214..291	CDD:188628	20/86 (23%)
crn-1	NP_491168.1	PTZ00217	1..351	CDD:240317	90/372 (24%)