Protein Alignment tos and mus201

DIOPT Version :10

• Sequence 1: NP_477145.1
• Gene: tos / 35119
• FlyBaseID: FBgn0015553
• Length: 732
• Species: Drosophila melanogaster
• Sequence 2: XP_061513536.1
• Gene: mus201 / 1279909
• VectorBaseID: AGAMI1_009840
• Length: 1443
• Species: Anopheles gambiae
• Alignment Length: 634
• Identity: 128/634 - (20%)
• Similarity: 219/634 - (34%)
• Gaps: 206/634 - (32%)

  Fly    81 HLP------AKALTEKRRRDSRKQSKERAAELLRLGRIEEARSHMRRCVDVTHDMALRLIRECRS 139
            |.|      |..|.|..|...|:::|:.     |:|            :.:|..|.    |:|..
Mosquito   935 HTPLELKRMALNLAETERELERERNKQS-----RIG------------LSITEQMR----RDCME 978

  Fly   140 R----NVDCIVAPYEADAQMAWLNRADVAQYIITEDSDLTLFGAKNIIFKLDLNGSGLLVEAEKL 200
            .    .|..||||.||:||.|:||:.|:....||:|||:.|||.|. ::|...|...|::|
Mosquito   979 LLQIFGVPFIVAPMEAEAQCAFLNQLDMTDGTITDDSDIWLFGGKK-VYKNFFNQQKLVLE---- 1038

  Fly   201 HLAMGCTEEKYHFD--KFRRMCILSGCDYLDSLPGIGLAKACKFILK-----------TEQEDMR 252
             ..:...|:.:..|  |..::.:|.|.||...:.|||...|.:.:..           :|...|.
Mosquito  1039 -FTIDGIEQMFQMDRKKLIQLALLVGSDYTTGIHGIGAVTALEILASFPPTPEQPGETSEMMSML 1102

  Fly   253 IALKKIPSYLN----------------MRNLEVDDDY-----IENFMK-----AEATFRHMFIYN 291
            ..|:|...:.:                ::|:|:.:.:     :|.:::     :|..|  .:.|.
Mosquito  1103 SGLRKFRDWWHHGRNGATGTRISLKSKLKNIEIGEGFPSTGVVEAYLQPTVDCSEEEF--TWGYP 1165

  Fly   292 PLERRMQRLCALEDYETDERYCSNAGT---LLEDSEQALHLALGNLNPFSMKRLDSWTPEKAWPT 353
            ..:|       |.||...:...|...|   ||.                .:||||.   .|:..:
Mosquito  1166 DADR-------LRDYARQKFGWSQTKTNDILLP----------------VLKRLDE---RKSQSS 1204

  Fly   354 PKNVKRSKHKSIWQTNFQSENTHTPKKENPCALFFKKVDFVGKTLNEEIEANQRLEQAKQTEAEL 418
            .||                              :||....||   :..::.::|::.|..|.|..
Mosquito  1205 IKN------------------------------YFKVQSAVG---HNRLKVSKRVQHAVDTMAGK 1236

  Fly   419 FNMYSFKAKRRRSPSREDSVDQERTPPPSPVHKSRHNPFA-------------KERTGEEANQRS 470
            .:.......::|||::          ...|..:.|..|.|             :|...::..:.|
Mosquito  1237 IDPEEEAKPKKRSPAK----------AKQPGGRKRKQPAAAKNAMETVDLEVIEEEEDDKKKEES 1291

  Fly   471 P---VVCENASLLR-LLSPKKASPLDGEAGVKKV-DSLKRSIFAKEQVQIRSRFFATQDEQTRLQ 530
            |   |..|:...:. ..:.:||....|.||.||. |:......||.:   |.|..|.:.:.|
Mosquito  1292 PKGAVAEEDDDFVEPAKTTQKAGRSRGAAGRKKANDAAATGTAAKPK---RGRKAAPKSDTT--- 1350

  Fly   531 REHLRDTENDDMDEQKLSSHSGHKKLRLVCKDIPGKNPIRQRCSSQISDGETDTDTTASSLLESQ 595
                .||:..:..|........|.     ..:|.|       ..:.|:....|:.....| :|.:
Mosquito  1351 ----NDTQQPEGGEPSTVQRPTHS-----LANIGG-------IIANINQQSADSMGVEES-VEGR 1398

  Fly   596 DKGVPSPLESQEDLNNSQPQIPTEGNTNSTTIRIKSLDLLLENSPEPTQ 644
            .|.:.:.:   .|.|.:.||            |:|...::.|...:..:
Mosquito  1399 RKRIGNKM---PDFNPAIPQ------------RVKDEQIMAERKRQAAE 1432

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tos	NP_477145.1	PIN_EXO1	1..202	CDD:350207	40/130 (31%)
		H3TH_EXO1	214..291	CDD:188628	19/115 (17%)
mus201	XP_061513536.1	None