Protein Alignment tos and tos

DIOPT Version :10

• Sequence 1: NP_477145.1
• Gene: tos / 35119
• FlyBaseID: FBgn0015553
• Length: 732
• Species: Drosophila melanogaster
• Sequence 2: XP_313789.6
• Gene: tos / 1274638
• VectorBaseID: AGAMI1_011047
• Length: 859
• Species: Anopheles gambiae
• Alignment Length: 903
• Identity: 351/903 - (38%)
• Similarity: 476/903 - (52%)
• Gaps: 219/903 - (24%)

  Fly     1 MGITGLIPFVGKASSQLHLKDIRGSTVAVDTYCWLHKGVFGCAEKLARGEDTDVYIQYCLKYVNM 65
            ||||||:||:.||||..||:::||..||:|||||||:|.|||||:||||:.||::||||||||.:
Mosquito     1 MGITGLLPFLEKASSACHLRELRGKCVAIDTYCWLHRGAFGCAERLARGDSTDMHIQYCLKYVQL 65

  Fly    66 LLSYDIKPILVFDGQHLPAKALTEKRRRDSRKQSKERAAELLRLGRIEEARSHMRRCVDVTHDMA 130
            |||::||||||||||||||||.||.:||:.|:.:::|.|||||||||:||||.:|||||:||:||
Mosquito    66 LLSHNIKPILVFDGQHLPAKAATEAKRREIRETARKRGAELLRLGRIDEARSFLRRCVDITHEMA 130

  Fly   131 LRLIRECRSRNVDCIVAPYEADAQMAWLNRADVAQYIITEDSDLTLFGAKNIIFKLDLNGSGLLV 195
            |:|::|||.|.|||||||||||||:|:|||.|:|||:|||||||.|||...|:|||||.|.|.||
Mosquito   131 LQLMQECRKRGVDCIVAPYEADAQLAYLNRTDIAQYVITEDSDLVLFGCNRILFKLDLTGHGRLV 195

  Fly   196 EAEKLHLAMGCTEEKYHFDKFRRMCILSGCDYLDSLPGIGLAKACKFILKTEQEDMRIALKKIPS 260
            ||.||||||||.|::|.|.|||.||||||||||||||||||.|||||:||||..|:|.||.|||:
Mosquito   196 EASKLHLAMGCREDRYKFAKFRYMCILSGCDYLDSLPGIGLGKACKFMLKTEDPDIRRALAKIPA 260

  Fly   261 YLNMRNLEVDDDYIENFMKAEATFRHMFIYNPLERRMQRLCALEDYETDERYCSNAGTLLEDSEQ 325
            |||||.|.|.::|.:.|:||:|||:||.:|:|::||..||...:|..|.|:||.|||..| |.:.
Mosquito   261 YLNMRQLSVTEEYKDEFLKADATFKHMVVYDPVQRRQTRLVDPDDEGTPEQYCCNAGKFL-DEKV 324

  Fly   326 ALHLALGNLNPFSMKRLDSWTPEKAWPTPKNVKRSKHKSIWQTNF-------QSENTHTPKKENP 383
            |..||:|||:|||::::|.|.|::| .......:::|.|||:.::       |::|:...:|...
Mosquito   325 AFQLAVGNLDPFSLRKMDDWHPDEA-DVDVAAGKNQHPSIWRKDYMLLRDAKQAQNSTQTQKPAT 388

  Fly   384 CALFFKK-VDFVGKTLNEEIEANQRLEQAKQTEAELFNMYSFKAKRRRSPSRE------------ 435
            .:.|.|: |..|...::         :...:|..::..:|..::. ...||:.
Mosquito   389 LSSFVKRAVHHVEHAVD---------QNTNETITDVLQIYGIQSP-DEPPSKRSCHAQKSFQSAE 443

  Fly   436 ----------------DSVDQERTPPPSPVHKSRHNPFAKERTGEEANQRSPVVCENASLL---R 481
                            :.::|.:||      |...||||              |..|.|||   .
Mosquito   444 SHVAIDYQDVEALDVLEQLEQPKTP------KRTRNPFA--------------VSPNKSLLSRDT 488

  Fly   482 LLSPKKASP-----LDGEAGVKKVD-SLKRS----------------------------IFAKEQ 512
            ||||.|.:|     |...:.||::| |.:||                            ..:|::
Mosquito   489 LLSPTKITPETRSLLHNVSPVKRIDYSQQRSQLVTTSIVGSGATSSRLSRFKTAHSKGVTISKDE 553

  Fly   513 VQIRSRFFATQDEQTRLQREHLRDTENDDMDEQKLSSHSGHK----KLRLVC---------KDIP 564
            .::.||||.||..::   :....||........|.|.....|    |..:||         |||.
Mosquito   554 PKVISRFFCTQQNKS---QSRTTDTSKGSNSIAKTSEDDSPKKSCTKQDVVCSLVSPTAIVKDIK 615

  Fly   565 GKNPI---------------------------RQRCSSQISDGETDTDTTASSLLESQDKGVP-S 601
            .|...                           |:|.......||     .::|:|...|.|:. |
Mosquito   616 SKRDSHALKATAIYLSSPEARLQSRGDRTPEKRKRVQIPPESGE-----RSNSVLGRFDSGIAMS 675

  Fly   602 PLESQED-----------LNNSQPQIPTEGNTNSTTIRIKSLDL--------LLENSP----EPT 643
            ...|.||           |::||.:   ..:...|.:.::..||        |.|..|    ...
Mosquito   676 ENNSNEDEGSLECDSGTGLSSSQKE---NDDVVITPVEMECSDLKPRNARLALFERRPAKQLSQL 737

  Fly   644 QESDRNNNDAIILLSDDSCSSDQRASSTSSSSQQ--------------------RQNFLPT---- 684
            .||..|..:..|:|.||| |||:.....::.:||                    :...||:
Mosquito   738 LESKDNIEELAIVLDDDS-SSDEDTKKRTADAQQAISAEKVHSPVKATHKTETVKPFQLPSTSTG 801

  Fly   685 -------SKRRVGLSKPSTA---KKGTPKSRTNGKLGAVSQNQTKLSMFGFQTKPVLK 732
                   ||.|....:|..:   |:..||: .|..||.   .||:|||||||.||.::
Mosquito   802 KVEASTKSKARSSCKRPGLSINRKQSVPKT-DNTNLGL---TQTRLSMFGFQKKPSMQ 855

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tos	NP_477145.1	PIN_EXO1	1..202	CDD:350207	143/200 (72%)
		H3TH_EXO1	214..291	CDD:188628	53/76 (70%)
tos	XP_313789.6	None