DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG31751 and hykk.2

DIOPT Version :9

Sequence 1:	NP_001286053.1	Gene:	CG31751 / 35118	FlyBaseID:	FBgn0086909	Length:	417	Species:	Drosophila melanogaster
Sequence 2:	NP_001107059.1	Gene:	hykk.2 / 559560	ZFINID:	ZDB-GENE-080204-31	Length:	355	Species:	Danio rerio

Alignment Length:	358	Identity:	108/358 - (30%)
Similarity:	189/358 - (52%)	Gaps:	21/358 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    63 RPKVEPEDVESLLRRLYGITISEVKEIVAYDDRNFFVKEDSNVKNPLIVTHCPHGYVLKILNSLD 127
            :|.:....|..:::||||:|.|.|:.:.:|||:||:|......:           :|||::||.|
Zfish     7 KPNLSHSQVTDVVKRLYGLTASVVRPLPSYDDQNFYVAPSEGGE-----------FVLKVMNSAD 60

  Fly   128 SKKEDFVDAQNQMLLYLGKHSVKCPRPVANATGKYYSVERLNGNSN----VVRLLEFIPGEIFHQ 188
            |:....::.|.|.:.:|.:..:.....:...||:..|:|..:....    :||||.::||....:
Zfish    61 SENVAVIELQTQSMNFLHQRGLPAQTALPTLTGQLMSLEEFDCGFGTQIYLVRLLTYLPGTTIAK 125

  Fly   189 VPVTKHLLYRSGEYLARLDRALKNFTH---QAYESHKTLWMLQSVPELRQFLYVVKDQEQRLICD 250
            :..:..:||..|:..|.||..|....|   :..:..:.:|.|.|:|.|.|:::|:.....:.|..
Zfish   126 ITCSPQILYDVGKMAATLDTVLLQMEHPNTRVLQRERFIWKLTSIPLLNQYVHVMDGDPVQKIVK 190

  Fly   251 EVIDAFEAKVLSQLPSMEHQIIHGDFNEQNIVVEQVPNQTEYTIKGVIDFGDTSKSPLIFEIGIA 315
            .||:.::.:|:.:||.....|.|||||:.|::|:. ...::|.|.|::||.|.|....|||:.|.
Zfish   191 GVIEKYQVQVMPKLPLFRECINHGDFNDHNLLVKP-DGPSKYKISGILDFADMSCGYFIFELAIT 254

  Fly   316 LTYMILQA-NDLANGGIFLSGYTSLNPIENSELALLKYCVTARFVQSLVMGLYTHTLHPTN-EYL 378
            :.||:::: ..|..||..::|:.|:.|:..:|...|.:.|..||.||||:..||....|.| |||
Zfish   255 IMYMMIESPTPLDVGGPVVAGWESVFPLNEAERDSLYWLVMCRFCQSLVLARYTVIQQPENEEYL 319

  Fly   379 LVTQEKGWKLLQKLWRESFDDIDELWASTGHQY 411
            ::|..||.:.|.:||....|:::..|..:..|:
Zfish   320 MITSRKGLRHLSRLWELGKDEVERRWFQSAQQF 352

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31751	NP_001286053.1	PKc_like	68..350	CDD:304357	83/289 (29%)
hykk.2	NP_001107059.1	SrkA	8..322	CDD:225213	99/325 (30%)
hykk.2	NP_001107059.1	PKc_like	12..297	CDD:304357	85/296 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170595456
Domainoid	1	1.000	120	1.000	Domainoid score	I5723
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H16057
Inparanoid	1	1.050	190	1.000	Inparanoid score	I3868
OMA	1	1.010	-	-		QHG48597
OrthoDB	1	1.010	-	-		D1519192at2759
OrthoFinder	1	1.000	-	-		FOG0007224
OrthoInspector	1	1.000	-	-		otm25796
orthoMCL	1	0.900	-	-		OOG6_105052
Panther	1	1.100	-	-	LDO	PTHR21064
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5476
SonicParanoid	1	1.000	-	-		X5330
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	14	13.940