DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31751 and Hykk

DIOPT Version :9

Sequence 1:	NP_001286053.1	Gene:	CG31751 / 35118	FlyBaseID:	FBgn0086909	Length:	417	Species:	Drosophila melanogaster
Sequence 2:	NP_001100293.1	Gene:	Hykk / 300723	RGDID:	1308677	Length:	376	Species:	Rattus norvegicus

Alignment Length:	375	Identity:	114/375 - (30%)
Similarity:	197/375 - (52%)	Gaps:	20/375 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    51 ADGDLLKPGSDVRPKVEPEDVESLLRRLYGITISEVKEIVAYDDRNFFVKEDSNVKNPLIVTHCP 115
            :.||..:..:..:|........:|:..::|..:|:::.:.:|||:||.|    ::......|..|
  Rat     2 SSGDDQQSQAFTKPTFTEAQASALVESIFGFKVSKIQPLPSYDDQNFHV----HISRSQETTDDP 62

  Fly   116 HGYVLKILNSLDSKKEDFVDAQNQMLLYL---GKHSVKCPRPVANATGKYYSVERLNGN---SNV 174
            ..|||||.|:..|:..|.::.||.::::|   |..:....|...:.|....|::  :|:   |.:
  Rat    63 VEYVLKISNTKSSQTPDLIEMQNHIIMFLRAAGFPTASVCRTKGDNTISLMSID--SGSEIKSYL 125

  Fly   175 VRLLEFIPGEIFHQVPVTKHLLYRSGEYLARLDRALKNFTH---QAYESHKTLWMLQSVPELRQF 236
            ||:|.::||....:|..:...||..|...||||:||::|.|   ........:|.|::||.|..:
  Rat   126 VRMLTYLPGRPIAEVATSHQQLYEIGRLAARLDKALEDFHHPKLNLLHRENFIWNLKNVPLLENY 190

  Fly   237 LYVVKDQEQRLICDEVIDAFEAKVLSQLPSMEHQIIHGDFNEQNIVVE---QVPNQTEYTIKGVI 298
            :..:.....|.|.::||..|:.:|:::|......|.|||.|:.||:|:   .......|.:.|::
  Rat   191 MGALSQSRNREIVEQVIQLFKEEVMTKLSHFRECINHGDLNDHNILVDLSKSASGDAVYQVSGIL 255

  Fly   299 DFGDTSKSPLIFEIGIALTYMILQA-NDLANGGIFLSGYTSLNPIENSELALLKYCVTARFVQSL 362
            ||||.|....:||:.|.:.||:::: :.:..||..|:|:.|:.|:...|...|...|.|||.|||
  Rat   256 DFGDMSYGYYVFEVAITIMYMMIESTSPIQVGGHVLAGFESVIPLTAVERDALFLLVCARFSQSL 320

  Fly   363 VMGLYTHTLHPTN-EYLLVTQEKGWKLLQKLWRESFDDIDELWASTGHQY 411
            ||..|:..|:|.| |||::|.:.|||.||:::......::|:|..|...|
  Rat   321 VMATYSCQLYPENKEYLMITAKTGWKHLQQMFDMGKKAVEEIWFETAKSY 370

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31751	NP_001286053.1	PKc_like	68..350	CDD:304357	84/294 (29%)
Hykk	NP_001100293.1	SrkA	13..346	CDD:225213	104/338 (31%)
Hykk	NP_001100293.1	PKc_like	33..311	CDD:304357	83/283 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166353345
Domainoid	1	1.000	121	1.000	Domainoid score	I5573
eggNOG	1	0.900	-	-		E1_COG2334
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H16057
Inparanoid	1	1.050	187	1.000	Inparanoid score	I3825
OMA	1	1.010	-	-		QHG48597
OrthoDB	1	1.010	-	-		D1519192at2759
OrthoFinder	1	1.000	-	-		FOG0007224
OrthoInspector	1	1.000	-	-		oto97354
orthoMCL	1	0.900	-	-		OOG6_105052
Panther	1	1.100	-	-	LDO	PTHR21064
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X5330
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	15	14.770