Protein Alignment CG43338 and Tex21

DIOPT Version :9

• Sequence 1: NP_001246080.1
• Gene: CG43338 / 35117
• FlyBaseID: FBgn0263079
• Length: 853
• Species: Drosophila melanogaster
• Sequence 2: NP_062758.3
• Gene: Tex21 / 80384
• MGIID: 1931131
• Length: 575
• Species: Mus musculus
• Alignment Length: 739
• Identity: 130/739 - (17%)
• Similarity: 248/739 - (33%)
• Gaps: 261/739 - (35%)

  Fly    93 GELA--EARAALCSKDADIENLRAQAARQTALIGSLQSRLQNSESREQAVQARCDSTIQTVQREK 155
            |.||  :.:.|..:|..:..:|...:||:...:......|:            .|.|...:...|
Mouse    14 GRLANSQTKEACEAKPPEARHLSHLSARENVPVACFDPPLE------------MDPTGNPIIHNK 66

  Fly   156 RSSDE----------RNKELICKIQHLETHMASEESQKEQIKAQLHDLLRRLSITLGMDVCDGNQ 210
            :::|.          :||.|:.::::|::.:..:|:..:::||:|.....|
Mouse    67 KAADPVHPDLASMLVKNKTLLAELRNLQSKLYVKETSLQEVKAELESYKER-------------- 117

  Fly   211 NSHATPECIISRAEEVMVELQRTKAKVSSTCDTLSSCE---NELLNLKSLANIEKQRLTAQLDGA 272
                       .|::   |||     :.|..|.:.|.:   :.|:.:|.|.|...|..
Mouse   118 -----------NAQQ---ELQ-----IISLRDDIKSLQDLIDSLMKMKILKNTNSQNF------- 156

  Fly   273 GNHNHELEGRCRQYERDLQIQRDRLTESEINGEKLKEELRGFESRCHRL----------QNNLD- 326
            |.||.:|.      ||.|.:: :||.|..:..|::|.||......|...          :::||
Mouse   157 GRHNWDLT------ERVLDLE-NRLREHLVGREEIKAELLEKRRSCPSSFSPYMNLKGPEDSLDI 214

  Fly   327 --------------------------RTQGDRLQFLRGL-------SNLLNVPEPC--------- 349
                                      :|.||:.|  :.|       |.|...|..|
Mouse   215 FPVKDNDEVYNLKRGSVVYSEGPIDGQTTGDKCQ--QDLIHQEKLTSELDRAPFSCGWETTPEQS 277

  Fly   350 ---------ETLIKDKLREILAENQAMHAQMHSLRDQLNSEHEKLKETQQTTECRLRSGEAQKCE 405
                     .||:.|.:..|||..:|:..::           :::...:|:.:|:..:.:.:...
Mouse   278 HHQDFLGQLATLLSDSIGPILATEEAVKERI-----------QEMGANEQSWKCKAEALQQEIQT 331

  Fly   406 LTERLEKCHAEIHTLRKDHMGLSEFLQRLALAMNWGECSAPPALGTDTNLMAENLLERAERLAAH 470
            ||:|||:.:                                            .|.|.|:....:
Mouse   332 LTKRLEQLY--------------------------------------------RLYEEAQTEENY 352

  Fly   471 CDHEAPHHHHHHHSPDKGCCDHGHGHGKLRRERSCHDIPLKESSSVYNLQ--RRVRVLREQVQRR 533
            .:.|.|               .|...||           :..|.|:.||.  |:....|.:....
Mouse   353 TEQERP---------------LGPLEGK-----------VAVSCSLRNLDVGRKKENSRTRTAHI 391

  Fly   534 DLHLELLRRKLAIIEDGARGKCMLQGERDEAVCRAKKAAKQVDKLSAQLADARSQIAEVKAQLAE 598
            |.|.:.  :||         :.:|..|::..:..|.:..:::.:|..||:|.:.....:|.||..
Mouse   392 DKHSKF--KKL---------EMLLDIEQNSKMAAAPRMEEKIQRLQKQLSDLKLSNKNMKTQLTR 445

  Fly   599 AVEYKITSLERARKIDELTTQICDLEDEKTRLLSQLNALKERLKSSCESNQNRRCRDEALINSMR 663
            ....|..::||.|   :..|::..|:::.......|....:..:......:.|..:..|   ...
Mouse   446 INVLKDKTIERLR---QSVTKVETLKEKTAAKTDNLKTPSDPAEQGARPEKERAHQTPA---QSL 504

  Fly   664 DDVSRLSSQLSDANQRLSHLQSFRTSVARTLHLR-DLPETDLLHRLQALCSAHQEFTMLSKRYET 727
            .|.|.:.:.|...:.|...|..||.::.:.|... ...:.|:::||:.:...::    :|||.:.
Mouse   505 PDPSTVRAVLKGLSGREQELADFREAIMKMLGFNMKTADKDVINRLKLVVQIYE----ISKRSKM 565

  Fly   728 ASPVGDHPCPRFDDPIPPSSHCRP 751
            |                  |||.|
Mouse   566 A------------------SHCEP 571

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG43338	NP_001246080.1	SMC_prok_B	<77..412	CDD:274008	73/395 (18%)
		SMC_prok_A	305..>644	CDD:274009	65/402 (16%)
Tex21	NP_062758.3	Smc	<88..480	CDD:224117	93/535 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167834091
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR18863
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	3	2.990