Protein Alignment CG43338 and C27D6.1

DIOPT Version :10

• Sequence 1: NP_001246080.1
• Gene: CG43338 / 35117
• FlyBaseID: FBgn0263079
• Length: 853
• Species: Drosophila melanogaster
• Sequence 2: NP_001352249.1
• Gene: C27D6.1 / 182964
• WormBaseID: WBGene00016160
• Length: 645
• Species: Caenorhabditis elegans
• Alignment Length: 666
• Identity: 139/666 - (20%)
• Similarity: 257/666 - (38%)
• Gaps: 166/666 - (24%)

  Fly    52 QLDTSCSNTGITVTEHHHGLDLTTTLRSELAALSYKKERLTGELAEARAALCSKDA-----DIEN 111
            |||.| |...:|.|.:..|..:|||||...:  .||:   .|:.:.:|..|.|.|:     .|..
 Worm    29 QLDLS-SEALVTSTLNIRGNKITTTLRPRTS--PYKR---AGDASMSREDLRSPDSVAATYTIRE 87

  Fly   112 LRAQAARQTAL-IGSLQSRLQNSESREQAVQARCDSTIQTVQREKRSSDERNKELICKIQHLETH 175
            .|::  |||.: :.||:.||:.:|...:.::|..:.......|..:...|...||...:|..|..
 Worm    88 NRSE--RQTKVKLESLERRLKANEKARKEIEAEAEKWKDRATRNSKRLPELELELAETVQAKEEW 150

  Fly   176 MASE---ESQKEQIKAQLHDLLRRLS--------------ITLGMDVCDGNQNSHATPECIISRA 223
            ....   |.|.:|:..:|:::.::|.              .||.:|. :..||.....:..:|:.
 Worm   151 QVKSQEMEIQNKQLVEELNEVQKKLEEIENSQKTFHQKVVSTLNLDE-EYFQNPDEEQDGSLSQF 214

  Fly   224 EEVMVELQRTKAKVSSTCDTLSSCENELLNLKSLANIEKQRLTAQLDGAGNH------------- 275
            .  |..|::...|....|.:|.. |||:|..|      .|:|::.|....||
 Worm   215 N--MDVLEQEIVKYQEKCISLKQ-ENEILKEK------LQQLSSSLTVNQNHVSTLMDHLEINKE 270

  Fly   276 -NHELEGRCRQYERDLQIQRDR---------LTESEINGEKLKEELRGFESRCHRL--------- 321
             :.|::|.|:   :::.|::|.         |..|.||.:|::.|:...|.||.|.
 Worm   271 QSREIQGICK---KEIAIRQDHENRINHDVTLLNSLINEQKMELEMLKAEIRCLRSYSQEMSQSN 332

  Fly   322 QNN---LDRTQGDRLQFLRGLSNLLNVPEPC-ETLIKDKLREILAENQAMHA-QMHSLRDQLNSE 381
            :||   |...:.:|...|..|:.|||..|.. |..:|..:|:::.|...... :..:.:...|:|
 Worm   333 KNNIILLKSAETERKSLLETLTVLLNSEEEATENNVKRTIRDLVRERDTEQTKRFEAEKAASNAE 397

  Fly   382 HEKLKETQQTTEC--RLRSGEAQKCELTERLEKCHAEIHTLRKDHMGLSEFLQRLALAMNWGECS 444
            ...|::.:|....  |.|..|.:..:..|::|:...|:.....:...|...:..|...::    .
 Worm   398 GVLLEQAKQQRNALFRARVSEEEYSKSMEKIEELEQELLASDLERKNLEHKIASLENCIS----K 458

  Fly   445 APPALGTDTNLMAENLLERAERLAAHCDHEAPHHHHHHHSPDKGCCDHGHGHGKLRRERSCHDIP 509
            ....|..:...:.:.:.:|.|.|.|                                :.|.:.:.
 Worm   459 VSQLLNVNVGGVFDAIFDRIEELIA--------------------------------QESVYRVV 491

  Fly   510 LKESSSVYNLQRRVRVLREQVQRRDLHLELLRRKLAIIEDGARGKCMLQGERDEAVCRAKKAAK- 573
            :.|:          |::.|.:.|   .|:.:|:      |...||.....::.:.......|||
 Worm   492 VNEN----------RLISENIFR---GLQSVRK------DFQSGKSGGGSDKKQPASPVAAAAKI 537

  Fly   574 -----------QVDKLSAQLADARSQIAEVKAQLAEAVEYKITSLERARKIDELTTQICDLEDEK 627
                       ::|||:..|      :|.:..:..:|.:.:.|:|:  ::::|...:|..||.||
 Worm   538 IQERHTLKTIDKMDKLNKDL------LATMTIETLKAADIEKTNLK--KRMNEQDARIRQLEREK 594

  Fly   628 TRLLSQLNALKERLKS 643
            ..        .||::|
 Worm   595 KE--------GERIRS 602

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG43338	NP_001246080.1	Smc	<77..>642	CDD:440809	127/638 (20%)
C27D6.1	NP_001352249.1	SMC_prok_B	145..>454	CDD:274008	69/321 (21%)