Protein Alignment Cyp310a1 and Cyp26c1

DIOPT Version :10

• Sequence 1: NP_609891.1
• Gene: Cyp310a1 / 35115
• FlyBaseID: FBgn0032693
• Length: 492
• Species: Drosophila melanogaster
• Sequence 2: NP_001098671.1
• Gene: Cyp26c1 / 546726
• MGIID: 2679699
• Length: 518
• Species: Mus musculus
• Alignment Length: 514
• Identity: 116/514 - (22%)
• Similarity: 191/514 - (37%)
• Gaps: 127/514 - (24%)

  Fly    30 PSEKAGITWSFLQK------------AYRREFRHVEAICEAYQSGKDRLLGIYCFFRPVLLVRNV 82
            |..|..:.|.|..:            :.||| |:....       |..|||     |||:.|...
Mouse    48 PLPKGSMGWPFFGETLHWLVQGSRFHSSRRE-RYGTVF-------KTHLLG-----RPVIRVSGA 99

  Fly    83 ELAQTILQQSNGHFSELKWDYIS-------------GYRRFNLLEKLAPMFGTKRLSEMFGQVQK 134
            |..:|||...: .....:|...:             |.......:.||.:|....|.:...::|.
Mouse   100 ENVRTILLGEH-RLVRSQWPQSAHILLGSHTLLGAVGEPHRQRRKVLARVFSRSSLEQFVPRLQG 163

  Fly   135 VGDHLIHHLLDRQGQG-CPQE--VDIQQKLRVYSVNIIANLIYGLDINNFEHEDHILTSYLSHSQ 196
            .        |.|:.:. |..:  |.:.|..:..:..:.|.::.||.:      |....:.|:|:.
Mouse   164 A--------LRREVRSWCAAQRPVAVYQAAKALTFRMAARILLGLQL------DEARCTELAHTF 214

  Fly   197 ASIQSFTLGRLPQKSSYTYRLRDLIKQSVELRE--DHGLIRKDILQLLVRFRNGNEVSGDKWQLE 259
            ..:.. .|..||....:: .||..|:...:|.|  |..:..|  ||             :|...|
Mouse   215 EQLVE-NLFSLPLDVPFS-GLRKGIRARDQLYEHLDEAVAEK--LQ-------------EKQTAE 262

  Fly   260 P-------INDADKL---LSIKRLAKVAEDLLKVSLDAVASTVTFTLLEILQEPLIVEKLRAEIK 314
            |       ||.|.:|   .|::.|.::|.:||..:....||..|..:|.:||.|..:.|::   :
Mouse   263 PGDALLLIINSARELGHEPSVQELKELAVELLFAAFFTTASASTSLILLLLQHPAAITKIQ---Q 324

  Fly   315 ELSNE---------------------NGQLKFEELNGLRYMDMCLKETLRKYPPLPIIERVCRKS 358
            |||.:                     ...|....|..|||:|..:||.||..||:....|...::
Mouse   325 ELSAQGLGRACTCTPRASGSPPDCGCEPDLSLAMLGRLRYVDCVVKEVLRLLPPVSGGYRTALRT 389

  Fly   359 YSLPNSKFTIDEGKTLMVPLLAMHRDEK-YFSEPMKYKPLRFLQTANDV----GQCEDKTKSNVF 418
            :.|..  :.|.:|.::|..:...|.... |.|.|..:.|.||...:.|.    |:..       :
Mouse   390 FELDG--YQIPKGWSVMYSIRDTHETAAVYRSPPEGFDPERFGVESGDARGSGGRFH-------Y 445

  Fly   419 IGFGIGGSQCVGQNFAKLVIKVALIKLLQNFHLELDANQVKTLKVSHRPAPFIHTKDGL 477
            |.||.|...|:||..|:.|:::..::|::....||.......::.    .|.:|..|||
Mouse   446 IPFGGGARSCLGQELAQAVLQLLAVELVRTARWELATPAFPVMQT----VPIVHPVDGL 500

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp310a1	NP_609891.1	CYP6-like	62..478	CDD:410679	108/470 (23%)
Cyp26c1	NP_001098671.1	cytochrome_P450	59..504	CDD:477761	112/503 (22%)