Protein Alignment Cyp310a1 and Cyp3a41a

DIOPT Version :10

• Sequence 1: NP_609891.1
• Gene: Cyp310a1 / 35115
• FlyBaseID: FBgn0032693
• Length: 492
• Species: Drosophila melanogaster
• Sequence 2: NP_059092.2
• Gene: Cyp3a41a / 53973
• MGIID: 1858451
• Length: 504
• Species: Mus musculus
• Alignment Length: 523
• Identity: 124/523 - (23%)
• Similarity: 233/523 - (44%)
• Gaps: 111/523 - (21%)

  Fly     2 WLLLPILLYSAVFLSVRHIYSHWRRRGFPSEK------------AGITWSFLQKAYRREFRHVEA 54
            |:||.|:|........| .:..::::|.|..|            .|: |.|..:.|
Mouse    12 WVLLAIILVLLYRYGTR-THGLFKKQGIPGPKPLPFLGTVLNYYKGL-WKFDMECY--------- 65

  Fly    55 ICEAYQSGKDRLLGIYCFFRPVLLVRNVELAQTILQQ-------SNGHFSEL------------- 99
              |.|  ||  ..|::....|:.::.:.|:.:.:|.:       :...|..:
Mouse    66 --EKY--GK--TWGLFDGQMPLFVITDPEMIKNVLVKECFSVFTNRREFGPVGIMSKAISISKDE 124

  Fly   100 KWDYISGYRRFNLLEKLAPMFGTKRLSEMFGQVQKVGDHLIHHLLDRQGQGCPQEVDIQQKLRVY 164
            :|      :|:..|  |:|.|.:.:|.|||..:::.||.|:.:|:....:|.|  |.::..|..|
Mouse   125 EW------KRYRAL--LSPTFTSGKLKEMFPVIEQYGDILVKYLMQEAEKGKP--VTMKDVLGAY 179

  Fly   165 SVNIIANLIYGLDINNFEHEDH----------------------ILTSYLS--HSQASIQSFTLG 205
            |:::|.:..:|:::::..:.:.                      :|..:|:  :...:|..|...
Mouse   180 SIDVITSTSFGVNVDSLNNPEDPFVEKAKGILRVDFFDPLVFSVVLFPFLTPVYEMLNICMFPKD 244

  Fly   206 RLPQKSSYTYRLRDLIKQSVELREDHGLIRKDILQLLVRFRNGNEVSGDKWQLEPINDADKLLSI 270
            .:.....:..|:::   ..::.::.|   |.|.|||::   |.:..|.||       |:.|.||.
Mouse   245 SIEFFKKFVNRMKE---SRLDSKQKH---RVDFLQLMM---NAHNNSKDK-------DSHKALSD 293

  Fly   271 KRLAKVAEDLLKVSLDAVASTVTFTLLEILQEPLIVEKLRAEIKELSNENGQLKFEELNGLRYMD 335
            ..:...:...:....:..:||::|||..:...|.|.:||:.||.|.........::.:..:.|:|
Mouse   294 MEITAQSIVFIFAGYETTSSTLSFTLYCLATHPDIQKKLQEEIDETLPNKAPPTYDTVMEMEYLD 358

  Fly   336 MCLKETLRKYPPLPIIERVCRKSYSLPNSKFTIDEGKTLMVPLLAMHRDEKYFSEPMKYKPLRFL 400
            |.|.||||.||....:||.|:|...| |..: |.:|.|:|:|..|:|.|.:::.||.:::|.||.
Mouse   359 MVLNETLRLYPIGNRLERFCKKDVEL-NGVY-IPKGSTVMIPSYALHHDPQHWPEPEEFQPERFS 421

  Fly   401 QTANDVGQCEDKTKSN--VFIGFGIGGSQCVGQNFAKLVIKVALIKLLQNFHLELDANQVKTLKV 463
            :        |:|...:  :::.||||...|:|..||.:.:|:||.|::|||..:........||:
Mouse   422 K--------ENKGSIDPYLYMPFGIGPRNCIGMRFAFMTMKLALTKVMQNFSFQPCQETQIPLKL 478

  Fly   464 SHR 466
            |.:
Mouse   479 SRQ 481

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp310a1	NP_609891.1	CYP6-like	62..478	CDD:410679	109/451 (24%)
Cyp3a41a	NP_059092.2	CYP3A	67..493	CDD:410743	110/455 (24%)