Protein Alignment Cyp310a1 and Cyp3a44

DIOPT Version :9

• Sequence 1: NP_609891.1
• Gene: Cyp310a1 / 35115
• FlyBaseID: FBgn0032693
• Length: 492
• Species: Drosophila melanogaster
• Sequence 2: NP_796354.1
• Gene: Cyp3a44 / 337924
• MGIID: 2449818
• Length: 504
• Species: Mus musculus
• Alignment Length: 524
• Identity: 130/524 - (24%)
• Similarity: 234/524 - (44%)
• Gaps: 109/524 - (20%)

  Fly     3 LLLPILLYSAVFLSVRHIY---SH--WRRRGFPSEK------------AGITWSFLQKAYRREFR 50
            |.|..|:..|:.|.:.:.|   :|  ::::|.|..|            .|| |.|..:.|
Mouse     7 LSLDTLVLLAIILVLLYRYGTRTHGLFKKQGIPGPKPLPFLGTVLNYYTGI-WKFDMECY----- 65

  Fly    51 HVEAICEAYQSGKDRLLGIYCFFRPVLLVRNVELAQTILQQ-------SNGHFSEL--------- 99
                  |.|  ||  ..|::....|:|::.:.|..:.:|.:       :...|..:
Mouse    66 ------EKY--GK--TWGLFDGQTPLLVITDPETIKNVLVKDCLSVFTNRREFGPVGIMSKAISI 120

  Fly   100 ----KWDYISGYRRFNLLEKLAPMFGTKRLSEMFGQVQKVGDHLIHHLLDRQGQGCPQEVDIQQK 160
                :|      :|:..|  |:|.|.:.||.|||..:::.||.|:.:|.....:|.|  |.::..
Mouse   121 SKDEEW------KRYRAL--LSPTFTSGRLKEMFPVIEQYGDILVKYLRQEAEKGMP--VAMKDV 175

  Fly   161 LRVYSVNIIANLIYGLDINNF---------EHEDHILTSYLSHSQASIQSFTL----------GR 206
            |..||:::|.:..:|:::::.         |.:..:...:......|:..|.|          ..
Mouse   176 LGAYSMDVITSTSFGVNVDSLNNPEDPFVEEAKKFLRVDFFDPLLFSVVLFPLLTPVYEMLNICM 240

  Fly   207 LPQKS-SYTYRLRDLIKQS-VELREDHGLIRKDILQLLVRFRNGNEVSGDKWQLEPINDADKLLS 269
            .|..| .:..:..|.:::| ::..:.|   |.|.|||::   |.:..|.||       |:.|..|
Mouse   241 FPNDSIEFFKKFVDRMQESRLDSNQKH---RVDFLQLMM---NSHNNSKDK-------DSHKAFS 292

  Fly   270 IKRLAKVAEDLLKVSLDAVASTVTFTLLEILQEPLIVEKLRAEIKELSNENGQLKFEELNGLRYM 334
            ...:...:...:....:..:||::|||..:...|.|.:||:|||.:..........:.:..:.|:
Mouse   293 NMEITVQSIIFISAGYETTSSTLSFTLYCLATHPDIQKKLQAEIDKALPNKATPTCDTVMEMEYL 357

  Fly   335 DMCLKETLRKYPPLPIIERVCRKSYSLPNSKFTIDEGKTLMVPLLAMHRDEKYFSEPMKYKPLRF 399
            ||.|.||||.||.:..:||||:|...| |..: |.:|..:|:|..|:|.|.:::.:|.:::|.||
Mouse   358 DMVLNETLRLYPIVTRLERVCKKDVEL-NGVY-IPKGSMVMIPSYALHHDPQHWPDPEEFQPERF 420

  Fly   400 LQTANDVGQCEDKTKSN--VFIGFGIGGSQCVGQNFAKLVIKVALIKLLQNFHLELDANQVKTLK 462
            .:        |:|...:  |::.||||...|:|..||.:.:|:|:.|:||||..:........||
Mouse   421 SK--------ENKGSIDPYVYLPFGIGPRNCIGMRFALMNMKLAVTKVLQNFSFQPCQETQIPLK 477

  Fly   463 VSHR 466
            :|.:
Mouse   478 LSRQ 481

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp310a1	NP_609891.1	p450	69..454	CDD:299894	107/427 (25%)
Cyp3a44	NP_796354.1	p450	39..494	CDD:278495	122/492 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0158
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X40
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.820