DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp310a1 and Cyp28d1

DIOPT Version :9

Sequence 1:	NP_609891.1	Gene:	Cyp310a1 / 35115	FlyBaseID:	FBgn0032693	Length:	492	Species:	Drosophila melanogaster
Sequence 2:	NP_608912.1	Gene:	Cyp28d1 / 33749	FlyBaseID:	FBgn0031689	Length:	502	Species:	Drosophila melanogaster

Alignment Length:	510	Identity:	116/510 - (22%)
Similarity:	213/510 - (41%)	Gaps:	88/510 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MWLLLPILLYSAVFLSVRHIYSHWRRRGFPSEKAGITWSFL--------QKAYRREFRHVEAICE 57
            ::::..||....|||:..  :|:|::||.|:.|   :|.|:        ||  |.....::.|.|
  Fly     8 LFVIAAILALIYVFLTWN--FSYWKKRGIPTAK---SWPFVGSFPSVFTQK--RNVVYDIDEIYE 65

  Fly    58 AYQSGKDRLLGIYCFFRPVLLVRNVELAQTIL--------QQSNGHFSELKWDYISGYRRFNLL- 113
            .|:: .|.::|::....|.|:|...|.|..|.        ......|::.|.|.|.....|.|.
  Fly    66 QYKN-TDSIVGVFQTRIPQLMVTTPEYAHKIYVSDFRSFHDNEMAKFTDSKTDPILANNPFVLTG 129

  Fly   114 -------EKLAPMFGTKRLSEMFGQVQKVGDHLIHHLLDRQGQGCP-QEVDIQQKLRVYSVNIIA 170
                   .::.|.....|:...:....:|....:.: :.||....| |.::.:.....|:..:|:
  Fly   130 EAWKERRAEVTPGLSANRVKAAYPVSLRVCKKFVEY-IRRQSLMAPAQGLNAKDLCLCYTTEVIS 193

  Fly   171 NLIYGLDINNF----------------EHEDHILTSYLSHSQASIQSFTLGRLPQK--SSYTYRL 217
            :.:.|:...:|                :....|..:.:::....|..|....|..|  :::.|
  Fly   194 DCVLGISAQSFTDNPTPMVGMTKRVFEQSFGFIFYTVVANLWPPITKFYSVSLFAKDVAAFFY-- 256

  Fly   218 RDLIKQSVELREDHGLI--RKDILQLLVRFRNGNEVSGDKWQLEPINDADKLLSIKRLAKVAEDL 280
             ||:::.:::|.:....  |.|.|..:::.:.                 .|.|:...|.......
  Fly   257 -DLMQKCIQVRRESPAAQQRDDFLNYMLQLQE-----------------KKGLNAAELTSHTMTF 303

  Fly   281 LKVSLDAVASTVTFTLLEILQEPLIVEKLRAEIKELSNENGQLKFEELNGLRYMDMCLKETLRKY 345
            |....:..|..:|.|||.:.:.|....|||.||     ...:|.||:::.|.:.:.|:.||||.:
  Fly   304 LTDGFETTAQVLTHTLLFLARNPKEQMKLREEI-----GTAELTFEQISELPFTEACIHETLRIF 363

  Fly   346 PPLPIIERVCRKSYSLPNS---KFTIDEGKTLMVPLLAMHRDEKYFSEPMKYKPLRFLQTANDVG 407
            .|:....:|..:...|.|.   ...:..|..:::|:.|:|.|.:|:.||..:||.|||   |..|
  Fly   364 SPVLAARKVVTEPCELTNKNGVSVKLRPGDVVIIPVNALHHDPQYYEEPQSFKPERFL---NING 425

  Fly   408 QCEDKTKSNVFIGFGIGGSQCVGQNFAKLVIKVALIKLLQNFHLELDANQVKTLK 462
            ..:......:|.|||.|...|.|..|:...||.||:::::||.::::.   ||.|
  Fly   426 GAKKYRDQGLFFGFGDGPRICPGMRFSLTQIKAALVEIVRNFDIKVNP---KTRK 477

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp310a1	NP_609891.1	p450	69..454	CDD:299894	92/424 (22%)
Cyp28d1	NP_608912.1	p450	35..477	CDD:278495	106/479 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45460860
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0158
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24292
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X40
	6	5.850