Protein Alignment Cyp310a1 and CYP51A1

DIOPT Version :10

• Sequence 1: NP_609891.1
• Gene: Cyp310a1 / 35115
• FlyBaseID: FBgn0032693
• Length: 492
• Species: Drosophila melanogaster
• Sequence 2: NP_000777.1
• Gene: CYP51A1 / 1595
• HGNCID: 2649
• Length: 509
• Species: Homo sapiens
• Alignment Length: 395
• Identity: 87/395 - (22%)
• Similarity: 165/395 - (41%)
• Gaps: 65/395 - (16%)

  Fly    95 HFSELKWDYISGYRRFNLLEKLAPMFGTKRLSEMFGQV-QKVGDHLIHHLLDRQGQGCPQEVDIQ 158
            ||.:          ..:::||     .||...|.:|:. :|.....:..|:......|....:|:
Human   173 HFKQ----------HVSIIEK-----ETKEYFESWGESGEKNVFEALSELIILTASHCLHGKEIR 222

  Fly   159 QKLRVYSVNIIANLIYGLDINNFEHEDHILTSYLSHSQASIQSFTLGRLPQKSSYTYR-LRDLIK 222
            .:|.    ..:|.|...|| ..|.|...:|..:|     .:.||      ::....:| ::|:..
Human   223 SQLN----EKVAQLYADLD-GGFSHAAWLLPGWL-----PLPSF------RRRDRAHREIKDIFY 271

  Fly   223 QSVELREDHGLIRKDILQLLV--RFRNGNEVSGDKWQLEPINDADKLLSIKRLAKVAEDLLKVSL 285
            ::::.|........||||.|:  .:::|..::.|:                 :|.:...||....
Human   272 KAIQKRRQSQEKIDDILQTLLDATYKDGRPLTDDE-----------------VAGMLIGLLLAGQ 319

  Fly   286 DAVASTVTFTLLEILQEPLIVEKLRAEIKELSNEN-GQLKFEELNGLRYMDMCLKETLRKYPPLP 349
            ...::|..:....:.::..:.:|...|.|.:..|| ..|.:::|..|..:|.|:|||||..||:.
Human   320 HTSSTTSAWMGFFLARDKTLQKKCYLEQKTVCGENLPPLTYDQLKDLNLLDRCIKETLRLRPPIM 384

  Fly   350 IIERVCRKSYSLPNSKFTIDEGKTLMVPLLAMHRDEKYFSEPMKYKPLRFLQTANDVGQCEDKTK 414
            |:.|:.|...::  :.:||..|..:.|......|.:..:.|.:.:.|.|:||.....|:
Human   385 IMMRMARTPQTV--AGYTIPPGHQVCVSPTVNQRLKDSWVERLDFNPDRYLQDNPASGE------ 441

  Fly   415 SNVFIGFGIGGSQCVGQNFAKLVIKVALIKLLQNFHLELDANQVKTLKVSHRPAPFIHTKDGLKV 479
            ...::.||.|..:|:|:|||.:.||.....:|:.:..:|......|:..:    ..|||.:...:
Human   442 KFAYVPFGAGRHRCIGENFAYVQIKTIWSTMLRLYEFDLIDGYFPTVNYT----TMIHTPENPVI 502

  Fly   480 KLKRR 484
            :.|||
Human   503 RYKRR 507

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp310a1	NP_609891.1	CYP6-like	62..478	CDD:410679	84/387 (22%)
CYP51A1	NP_000777.1	CYP51-like	94..505	CDD:410668	84/391 (21%)