Protein Alignment Cyp310a1 and cyp3a5

DIOPT Version :10

• Sequence 1: NP_609891.1
• Gene: Cyp310a1 / 35115
• FlyBaseID: FBgn0032693
• Length: 492
• Species: Drosophila melanogaster
• Sequence 2: XP_012819594.1
• Gene: cyp3a5 / 100037874
• XenbaseID: XB-GENE-5821575
• Length: 510
• Species: Xenopus tropicalis
• Alignment Length: 538
• Identity: 137/538 - (25%)
• Similarity: 237/538 - (44%)
• Gaps: 125/538 - (23%)

  Fly     3 LLLPILLYSAVFLSVRHIYSHWRRRGFPSEKAGIT-----WSFLQKAYRREFRH--VEAICEAYQ 60
            |||.:|.|.|::     .|..::|.|.|    |.|     .:||..      ||  :|...|.::
 Frog    17 LLLTLLAYYAIW-----PYKLFKRYGIP----GPTPIPFIGTFLGN------RHGLMEFDMECFK 66

  Fly    61 S-GKDRLLGIYCFFRPVL-LVRNVELAQTILQQSNGHFSELKWDYISGYRRFNLL---------- 113
            . ||  :.|||...:|:| :|..|.:...::::...:|:..:...:||..:.::|
 Frog    67 KYGK--VWGIYEGQKPLLAIVDPVIIKSIMVKECYTNFTNRRDFGLSGPLKSSVLISKDEQWKRI 129

  Fly   114 -EKLAPMFGTKRLSEMFGQVQKVGDHL---IHHLLDRQGQGCPQEVDIQQKLRVYSVNIIANLIY 174
             ..|:|.|.:.:|.:||..:...|:.|   ||..::.:     :.:|::.....||::|:.:..:
 Frog   130 RTVLSPTFTSGKLKQMFPLMNHYGELLVKNIHKKINNK-----EPLDMKHIFGSYSMDIVLSTSF 189

  Fly   175 GLDINNFEH-EDHILTS-------------YLSHSQASIQSFTLGRLPQKSSYTY---RLRDLIK 222
            .:::::..: .|..:|:             :|    .||....|..|..|.::.:   ::.:..|
 Frog   190 SVNVDSMNNPNDPFVTNARNLFTFSFFNPLFL----ISILCPFLVPLLDKMNFCFLSLKILNFFK 250

  Fly   223 QSVE---------LREDHGLIRKDILQLLV--RFRNGNEV-SGDKWQLEPINDADKLLSIKRLAK 275
            .:|.         ..||    |.|.|||:|  :...|..| ..:|...:.::|.:.|
 Frog   251 DAVASIKKKRQKGTHED----RVDFLQLMVDAQSNEGKSVPEEEKHGYKELSDTEIL-------- 303

  Fly   276 VAEDLLKV--SLDAVASTVTFTLLEILQEPLIVEKLRAEIKELSNENGQLKFEELNGLRYMDMCL 338
             |:.|:.:  ..:..::|:.|....|...|.:..||..||..|........::.|..:.||||.:
 Frog   304 -AQSLIFIMAGYETTSTTLMFLAYNIATHPDVQRKLEEEIDALLPNKAPPTYDALMKMEYMDMVI 367

  Fly   339 KETLRKYPPLPIIERVCRKSYSLPNSKFTIDEGKTLMVPLLAMHRDEKYFSEPMKYKPLRFLQTA 403
            .|:||.:||...|:|||:|:..:  :..||..|..::|||.|:|.:.:.:.||.:::|.||
 Frog   368 NESLRMFPPAIRIDRVCKKTMEI--NGVTIPAGVVIVVPLFALHLNPEIWPEPEEFQPERF---- 426

  Fly   404 NDVGQCEDKTKSNV-------FIGFGIGGSQCVGQNFAKLVIKVALIKLLQNFHLELDANQVKTL 461
                     :|.|.       |:.||:|...|:|..||.:.:||||..|||||.||       |.
 Frog   427 ---------SKENQKNQDPYNFLPFGVGPRNCIGMRFALVNMKVALTILLQNFRLE-------TC 475

  Fly   462 KVSHRPAPF-IHTKDGLK 478
            |  ..|.|. |.||..||
 Frog   476 K--DTPVPLKICTKGYLK 491

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp310a1	NP_609891.1	CYP6-like	62..478	CDD:410679	117/469 (25%)
cyp3a5	XP_012819594.1	cytochrome_P450	67..498	CDD:477761	119/473 (25%)