Protein Alignment IFT46 and Ift46

DIOPT Version :9

• Sequence 1: NP_609890.2
• Gene: IFT46 / 35114
• FlyBaseID: FBgn0032692
• Length: 416
• Species: Drosophila melanogaster
• Sequence 2: NP_076320.2
• Gene: Ift46 / 76568
• MGIID: 1923818
• Length: 301
• Species: Mus musculus
• Alignment Length: 354
• Identity: 98/354 - (27%)
• Similarity: 144/354 - (40%)
• Gaps: 126/354 - (35%)

  Fly    63 FQNNSTDDDGLLQDIIDHDDEAE-DSEDDDDSEMQLPQGMTMGVGMTGLVPGPNMQKRPGSNRSS 126
            |..|..|||         ||.:| ||:||||.|
Mouse    28 FSENDDDDD---------DDSSETDSDDDDDDE-------------------------------- 51

  Fly   127 KQVPDDTLSSGSEEAAMGGRMGSGGARGGAKLPHQKLTLPMRGSASGAGRSKRQDDQSFIMSADK 191
                        |..|                       |:.|:...|                .
Mouse    52 ------------EHGA-----------------------PLEGAYDPA----------------D 65

  Fly   192 WEDLSVPGELKELFPYIVKYTPQTIDTPFHLQPFIPEFVPAVGDVDALLKVQAP---PLLQPQRQ 253
            :|.|.|..|:||||.||.:||||.||....|:||||:|:|||||:||.|||..|   |
Mouse    66 YEHLPVSAEIKELFEYISRYTPQLIDLDHKLKPFIPDFIPAVGDIDAFLKVPRPDGKP------- 123

  Fly   254 KDLNDHLEKLGLWLLDEPSGAQSEPSLLNMKLRSVLSGSMGRN-PRHASSASLVPTARSGKDIEK 317
                ||   |||.:|||||..||:|::|::.|   ...|...| .:|....||....::.|.|:.
Mouse   124 ----DH---LGLLVLDEPSTKQSDPTVLSLWL---TENSKQHNITQHMKVKSLEDAEKNPKAIDT 178

  Fly   318 WITEVEQVHMTQ---SMYDVQPRKDIDALLEDWPRSFGDEQTINALDQAYRSCLQQNISVAEYVG 379
            ||..:.::|.::   :::..:|..|||.|:::|...|.:     .|.:.....::.:.|:|||:.
Mouse   179 WIESISELHRSKPPATVHYTRPMPDIDTLMQEWSPEFEE-----LLGKVSLPTVEIDCSLAEYID 238

  Fly   380 VLCERFGVEGPLESQADYIHNVQTLFALY 408
            ::|....:  |.....  |.::..||:||
Mouse   239 MICAILDI--PFYKSR--IQSLHLLFSLY 263

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
IFT46	NP_609890.2	IFT46_B_C	189..409	CDD:289115	78/227 (34%)
Ift46	NP_076320.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..66		20/129 (16%)
		IFT46_B_C	62..264	CDD:403511	79/244 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167831939
Domainoid	1	1.000	118	1.000	Domainoid score	I5870
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	117	1.000	Inparanoid score	I4792
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0006643
OrthoInspector	1	1.000	-	-		oto94955
orthoMCL	1	0.900	-	-		OOG6_104593
Panther	1	1.100	-	-	LDO	PTHR13376
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3191
SonicParanoid	1	1.000	-	-		X4873
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	11	10.920