DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Atac2 and NAT8

DIOPT Version :9

Sequence 1:	NP_609889.1	Gene:	Atac2 / 35113	FlyBaseID:	FBgn0032691	Length:	774	Species:	Drosophila melanogaster
Sequence 2:	NP_003951.3	Gene:	NAT8 / 9027	HGNCID:	18069	Length:	227	Species:	Homo sapiens

Alignment Length:	123	Identity:	29/123 - (23%)
Similarity:	51/123 - (41%)	Gaps:	19/123 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   641 PAVNALLQSTFWPNIDVSECLSYPDYSV-----------VALYKKLVIG-CGFL-VPDVGYNEAY 692
            ||:..|.:..:...:|::.|....|.:.           ||..::.|:| .|.| |.|....|..
Human    72 PALWFLAKKPWTEYVDMTLCTDMSDITKSYLSERGSCFWVAESEEKVVGMVGALPVDDPTLREKR 136

  Fly   693 ISF--MAVRPCWQRSGIASFMLYHLIQTCMSKDITLHVSATN----AAVMLYQKFGFK 744
            :..  :.|....:|.|||..::..::|....:..:..:..|.    :|:.|||..|||
Human   137 LQLFHLFVDSEHRRQGIAKALVRTVLQFARDQGYSEVILDTGTIQLSAMALYQSMGFK 194

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Atac2	NP_609889.1	PHD	14..63	CDD:214584
		rimI	639..753	CDD:273701	29/123 (24%)
		Acetyltransf_1	676..744	CDD:278980	19/75 (25%)
NAT8	NP_003951.3	RimI	<101..200	CDD:223532	23/94 (24%)
NAT8	NP_003951.3	Acetyltransf_1	113..194	CDD:278980	19/80 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0456
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900