DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Atac2 and Naa60

DIOPT Version :9

Sequence 1:	NP_609889.1	Gene:	Atac2 / 35113	FlyBaseID:	FBgn0032691	Length:	774	Species:	Drosophila melanogaster
Sequence 2:	XP_008765741.1	Gene:	Naa60 / 363545	RGDID:	1308915	Length:	295	Species:	Rattus norvegicus

Alignment Length:	300	Identity:	63/300 - (21%)
Similarity:	100/300 - (33%)	Gaps:	104/300 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly   472 IPSENLKLINAYEEQKLYQRL---DRIFALEHQCHISIP-AYVRRLYRKLSLRKWKRDHNRHIFN 532
            :||..|..::.        ||   |.|..::|.|....| .|....||.::       .|:..|:
  Rat     5 VPSSALSEVSL--------RLLCHDDIDTVKHLCGDWFPIEYPDSWYRDIT-------SNKKFFS 54

  Fly   533 LDEHIDPLGRARLKMLGHQKAEILDRYQLLAHSRQDARSSFHARLAGCTQYELFESPYSQRVLHP 597
            |      ....|..::|...|||.:|.::  |.    .:..|..|||
  Rat    55 L------AATYRGAIVGMIVAEIKNRTKI--HK----ETGIHCVLAG------------------ 89

  Fly   598 FIFRSETMAPPWLKL----MCELQHRVNGSHPTRSTIDFCFVRPQHIPAVNALLQSTFWPNIDVS 658
                        |||    :|.....|....|.|..::..                    :::|.
  Rat    90 ------------LKLRPACLCLSSAGVQDRAPMRGLLEVV--------------------SLEVK 122

  Fly   659 ECLSYPDYSVVALYKKLVIGCGFLVP---DVGYNEAYISFMAVRPCWQRSGIASFMLY----HLI 716
            |         |:|.::||...|.::.   .|....|||..:.|...:::.||.|.:|.    |:.
  Rat   123 E---------VSLKQQLVGRDGDILASSFSVDTQVAYILSLGVVKEFRKHGIGSLLLESLKDHIS 178

  Fly   717 QTCMS--KDITLHVSAT-NAAVMLYQKFGFKMEEIILDFY 753
            .|...  |.|.|||..| |.|:..|:...|:....:..:|
  Rat   179 TTAQDHCKAIYLHVLTTNNTAINFYENRDFRQHHYLPYYY 218

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Atac2	NP_609889.1	PHD	14..63	CDD:214584
		rimI	639..753	CDD:273701	28/123 (23%)
		Acetyltransf_1	676..744	CDD:278980	22/77 (29%)
Naa60	XP_008765741.1	Acetyltransf_1	<137..208	CDD:395465	20/70 (29%)
Naa60	XP_008765741.1	TIM	<192..>256	CDD:419668	6/26 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0456
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810