DRSC/TRiP Functional Genomics Resources

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Protein Alignment Atac2 and NAA30

DIOPT Version :9

Sequence 1:NP_609889.1 Gene:Atac2 / 35113 FlyBaseID:FBgn0032691 Length:774 Species:Drosophila melanogaster
Sequence 2:NP_001011713.2 Gene:NAA30 / 122830 HGNCID:19844 Length:362 Species:Homo sapiens


Alignment Length:513 Identity:93/513 - (18%)
Similarity:149/513 - (29%) Gaps:191/513 - (37%)


- Green bases have known domain annotations that are detailed below.


  Fly   265 ETLPGPPILQENIAPPSQKEEEPQNQPMSMVQAGLMDFLAESLESDDFTMFGNLPGIMPPPLIGA 329
            |..|||..|....|||:....||:    ....||.........|.||....|   |....|..|.
Human     3 EVPPGPSSLLPPPAPPAPAAVEPR----CPFPAGAALACCSEDEEDDEEHEG---GGSRSPAGGE 60

  Fly   330 GKNDFFMTEPLLHAP--------LNNEGLFDMDTNFAIPNTADETKPISTEEPAAESSEEQKEGE 386
            .........|.|..|        ||  ||...:........:.::|.:|..|.||.::       
Human    61 SATVAAKGHPCLRCPQPPQEQQQLN--GLISPELRHLRAAASLKSKVLSVAEVAATTA------- 116

  Fly   387 VEDEKPEEDESPDYQPRIVQVTNYQAQEANESIKEEPLEEIMQDDDVTTNSKSSILEPCKPSGFV 451
                      :||..||..     ..:.|.....|.|      ...:::|:::::..|.      
Human   117 ----------TPDGGPRAT-----ATKGAGVHSGERP------PHSLSSNARTAVPSPV------ 154

  Fly   452 RQPRRNWPWLQEAQDPDDMAIPSENLKLINAYEEQKLYQRLDRIFALEHQCHISIPAYVRRLYRK 516
                       ||....|.|.....|......||::..::                  ||.|...
Human   155 -----------EAAAASDPAAARNGLAEGTEQEEEEEDEQ------------------VRLLSSS 190

  Fly   517 L----SLRKWKRDHNRHIFNLDEHIDPLGRARLKMLGHQKAEILDRYQLLAHSRQDARSSFHARL 577
            |    |||                 .|.||           |:                      
Human   191 LTADCSLR-----------------SPSGR-----------EV---------------------- 205

  Fly   578 AGCTQYELFESPYSQRVLHPFIFRSETMAPPWLKLMCELQHRVNGSHPTRSTIDFCFVRPQHIPA 642
                      .|...|.:....:.||...|..::|:               |.|..  .|..|..
Human   206 ----------EPGEDRTIRYVRYESELQMPDIMRLI---------------TKDLS--EPYSIYT 243

  Fly   643 VNALLQSTFWPNIDV-----SECLSYPDYSVVA---LYKKLVIGCGFLVPDVGYNEAYISFMAVR 699
            ....:.:  ||.:..     .||:.    ::|.   ::||:            :...||:.:||.
Human   244 YRYFIHN--WPQLCFLAMVGEECVG----AIVCKLDMHKKM------------FRRGYIAMLAVD 290

  Fly   700 PCWQRSGIASFMLYHLIQTCMSKD---ITLHVSATN-AAVMLYQKFGFKMEEIILDFY 753
            ..::|:||.:.::...|...:..|   :.|....|| :|:.||:..||..::.:..:|
Human   291 SKYRRNGIGTNLVKKAIYAMVEGDCDEVVLETEITNKSALKLYENLGFVRDKRLFRYY 348

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Atac2NP_609889.1 PHD 14..63 CDD:214584
rimI 639..753 CDD:273701 25/125 (20%)
Acetyltransf_1 676..744 CDD:278980 16/71 (23%)
NAA30NP_001011713.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..26 9/22 (41%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 38..88 13/54 (24%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 113..182 17/113 (15%)
RimI 209..362 CDD:223532 34/175 (19%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG0456
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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