DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Atac2 and nat8l2

DIOPT Version :9

Sequence 1:	NP_609889.1	Gene:	Atac2 / 35113	FlyBaseID:	FBgn0032691	Length:	774	Species:	Drosophila melanogaster
Sequence 2:	NP_001373330.1	Gene:	nat8l2 / 100004652	ZFINID:	ZDB-GENE-131127-633	Length:	229	Species:	Danio rerio

Alignment Length:	169	Identity:	41/169 - (24%)
Similarity:	58/169 - (34%)	Gaps:	61/169 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly   632 FCFVRPQHIPA-----VNALLQSTF-----------W-------------------PNIDVSECL 661
            :...||.||..     |:|.:.||:           |                   .|.|:.:..
Zfish    39 YAMTRPLHITISLFIYVSAYILSTYSLVLSLMCGGSWIGLVYFCCHEFYAGYVRSRLNTDMKDIS 103

  Fly   662 SY----PDYSVVALYKKL-----VIGCGFLVPDVG---YNEAYISFMAVRPCWQRSGIASFMLYH 714
            :|    ||........::     |:|...:....|   |.|.|  .|.|....:|:|:.    ..
Zfish   104 AYYLENPDNCFWVAEAEIEGRPQVLGMVAVEGKKGSEKYGELY--RMIVSSACRRTGLG----VK 162

  Fly   715 LIQT----CMSK---DITLHVSAT-NAAVMLYQKFGFKM 745
            |.||    |..:   .|.|..|:| .|||.||.|.|||:
Zfish   163 LAQTAEDFCRERGFSKIMLSTSSTQKAAVALYFKLGFKL 201

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Atac2	NP_609889.1	PHD	14..63	CDD:214584
		rimI	639..753	CDD:273701	39/162 (24%)
		Acetyltransf_1	676..744	CDD:278980	25/78 (32%)
nat8l2	NP_001373330.1	Acetyltransf_1	84..199	CDD:395465	29/120 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0456
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900