Protein Alignment CG10333 and DBP2

DIOPT Version :10

• Sequence 1: NP_609888.2
• Gene: CG10333 / 35112
• FlyBaseID: FBgn0032690
• Length: 822
• Species: Drosophila melanogaster
• Sequence 2: NP_014287.3
• Gene: DBP2 / 855611
• SGDID: S000005056
• Length: 546
• Species: Saccharomyces cerevisiae
• Alignment Length: 555
• Identity: 198/555 - (35%)
• Similarity: 289/555 - (52%)
• Gaps: 86/555 - (15%)

  Fly   282 GEDTSIDYNNLYKERHHVQFFGRGNVAGIDIKEQKRTQSKFYGDLLE--------KRRTEAEKEQ 338
            |.|...:..| ||.|            |.|.:..:.:....|.|..:        ..|:...:.|
Yeast     5 GRDQQYNKTN-YKSR------------GGDFRGGRNSDRNSYNDRPQGGNYRGGFGGRSNYNQPQ 56

  Fly   339 EKVRLKKMKRKEDKQKWDD--------------RHWS--EKENDEMTERDWRIFREDYNVTIKGG 387
            |.:          |..||:              .|.|  ::.:.|:.:     ||::..:||.|.
Yeast    57 ELI----------KPNWDEELPKLPTFEKNFYVEHESVRDRSDSEIAQ-----FRKENEMTISGH 106

  Fly   388 RIPNPIRSWNESGFPKEIIDIIDKVGYKEPTPIQRQAIPIGLQNRDIIGVAETGSGKTLAFLIPL 452
            .||.||.:::|:|||..:::.:...|:.:||.||.|..|:.|..||::|:|.|||||||::.:|.
Yeast   107 DIPKPITTFDEAGFPDYVLNEVKAEGFDKPTGIQCQGWPMALSGRDMVGIAATGSGKTLSYCLPG 171

  Fly   453 LSWIQSLPKIERLEDVDQGPYAIIMAPTRELAQQIEEETTKFGQPLGIRTVVVVGGLSREEQGFR 517
            :..|.:.|    |.....||..:::|||||||.||:.|.:|||....||...|.||:.:.:|...
Yeast   172 IVHINAQP----LLAPGDGPIVLVLAPTRELAVQIQTECSKFGHSSRIRNTCVYGGVPKSQQIRD 232

  Fly   518 LRLGCEIVIATPGRLIDVLENRYLVLNQCTYIVLDEADRMIDMGFEPDVQKILEYMPVTNLKPDT 582
            |..|.||||||||||||:||.....|.:.||:||||||||:||||||.::||     |..::||
Yeast   233 LSRGSEIVIATPGRLIDMLEIGKTNLKRVTYLVLDEADRMLDMGFEPQIRKI-----VDQIRPD- 291

  Fly   583 EEAEDETKLMENFYTKKKYRQTVMFTATMPPAVERLARTYLRRPATVYIGSVG-KPTERTEQIVY 646
                               |||:|::||.|..|::||..||..|..|.:||:. ..:....|||.
Yeast   292 -------------------RQTLMWSATWPKEVKQLAADYLNDPIQVQVGSLELSASHNITQIVE 337

  Fly   647 MMGENDKRKKL---MEILSRKIDPPVIIFVNQKKGADVLAKGLEKLGYNSCTLHGGKGQEQREYA 708
            ::.:.:||.:|   :|..|:..:...:||.:.|:..|.:.|.|.:.|:.:..:||.|.|.:|::.
Yeast   338 VVSDFEKRDRLNKYLETASQDNEYKTLIFASTKRMCDDITKYLREDGWPALAIHGDKDQRERDWV 402

  Fly   709 LAALKSGAKDILVATDVAGRGIDIKDVSLVINYDMAKTIEDYTHRIGRTGRAGKTGCAISFVTKD 773
            |...::|...|:||||||.||||:|.::.||||||...||||.||||||||||.||.||||.|:.
Yeast   403 LQEFRNGRSPIMVATDVAARGIDVKGINYVINYDMPGNIEDYVHRIGRTGRAGATGTAISFFTEQ 467

  Fly   774 DSALFYDLKQCVSASPVSTCPPELMNHPEAQHKPG 808
            :..|...|.. :........||||:.:....:..|
Yeast   468 NKGLGAKLIS-IMREANQNIPPELLKYDRRSYGGG 501

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10333	NP_609888.2	DUF5401	<66..354	CDD:375164	14/79 (18%)
		SrmB	395..783	CDD:440279	165/391 (42%)
DBP2	NP_014287.3	DEAD-like_helicase_N	4..492	CDD:475120	197/544 (36%)