DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10333 and AT2G33730

DIOPT Version :9

Sequence 1:	NP_609888.2	Gene:	CG10333 / 35112	FlyBaseID:	FBgn0032690	Length:	822	Species:	Drosophila melanogaster
Sequence 2:	NP_180929.1	Gene:	AT2G33730 / 817938	AraportID:	AT2G33730	Length:	733	Species:	Arabidopsis thaliana

Alignment Length:	841	Identity:	374/841 - (44%)
Similarity:	480/841 - (57%)	Gaps:	174/841 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 KKRRSRSRERHRED--------RPAVGNPR---------DRERERDRVRERDRQFDREKERRQRR 52
            ||:|.....:.|:|        |..:|.|.         |..|::||.|:|||  |||::|.:.|
plant    30 KKQREELALKRRQDQISEQRVRREQLGRPEPETEDVSNGDTNRDKDRDRDRDR--DRERDRDRER 92

  Fly    53 SRSREDRNRRRSPERQRPRDNVRERSRERGGGAGGGGGGGAEKKAKMDTGDAPPKPLIVDDEEQQ 117
            .|.| ||:|.|  :|.|.||..|||.|||                               |..::
plant    93 DRGR-DRDRDR--DRDRDRDRERERDRER-------------------------------DRRER 123

  Fly   118 DGKEAKVKKEPLSLEELLDKKKREEEARSKPVFLTKEQRALEAIKRRQEEVERQRAAHDAAREQM 182
            |       :||       |::.||:|                    |:|||:        |||:
plant   124 D-------REP-------DRRNREKE--------------------REEEVK--------AREK- 145

  Fly   183 AAASKVSISMGTAMASGAPPPAIVAPPPKPDRRERGGGRDRGDRIDRGERGDDKRAEDLTHKDKE 247
                                                                 .|.|.|..::||
plant   146 -----------------------------------------------------ARVEKLVEREKE 157

  Fly   248 KELEAIRERYLGIIKKKRRVRRLNDR-KFVFDWDAGEDTSIDYNNLYKERHHVQ-FFGRGNVAGI 310
            |||:||:|:|||..|.|:||.|.::: :|.|||:..||||.|.|.||:..|..| .||||..||:
plant   158 KELDAIKEQYLGGKKPKKRVIRPSEKFRFSFDWENTEDTSRDMNVLYQNPHEAQLLFGRGFRAGM 222

  Fly   311 DIKEQKRTQSKFYGDLLEKRRTE---AEKEQEKVRLKKMKRKEDKQKWD------DRHWSEKEND 366
            |.:|||:..:|...::.::.|.:   .||.:|..  .:..|:|....:|      |||||:|..:
plant   223 DRREQKKQAAKHEKEMRDEIRKKDGIVEKPEEAA--AQRVREEAADTYDSFDMRVDRHWSDKRLE 285

  Fly   367 EMTERDWRIFREDYNVTIKGGRIPNPIRSWNESGFPKEIIDIIDKVGYKEPTPIQRQAIPIGLQN 431
            |||||||||||||:|::.||.|||.|:|||.||....|::..:::.|||:|:|||..|||:|||.
plant   286 EMTERDWRIFREDFNISYKGSRIPRPMRSWEESKLTSELLKAVERAGYKKPSPIQMAAIPLGLQQ 350

  Fly   432 RDIIGVAETGSGKTLAFLIPLLSWIQSLPKIERLEDVDQGPYAIIMAPTRELAQQIEEETTKFGQ 496
            ||:||:||||||||.||::|:|::|..||.:.. |:..:||||::|||||||||||||||.||..
plant   351 RDVIGIAETGSGKTAAFVLPMLAYISRLPPMSE-ENETEGPYAVVMAPTRELAQQIEEETVKFAH 414

  Fly   497 PLGIRTVVVVGGLSREEQGFRLRLGCEIVIATPGRLIDVLENRYLVLNQCTYIVLDEADRMIDMG 561
            .||.|...:|||.|.||||.::..||||||||||||||.||.||.|||||.|:||||||||||||
plant   415 YLGFRVTSIVGGQSIEEQGLKITQGCEIVIATPGRLIDCLERRYAVLNQCNYVVLDEADRMIDMG 479

  Fly   562 FEPDVQKILEYMPVTNLKPDTEEAE-DETKLMENFYTKKKYRQTVMFTATMPPAVERLARTYLRR 625
            |||.|..:|:.||.:||||:.||.| ||         ||.||.|.||:|||||.||||||.|||.
plant   480 FEPQVAGVLDAMPSSNLKPENEEEELDE---------KKIYRTTYMFSATMPPGVERLARKYLRN 535

  Fly   626 PATVYIGSVGKPTERTEQIVYMMGENDKRKKLMEILSRKIDPPVIIFVNQKKGADVLAKGLEKLG 690
            |..|.||:.||.|:...|.|.||.|::|..:|.::|....:...|:|||.||..|.:||.|:|.|
plant   536 PVVVTIGTAGKTTDLISQHVIMMKESEKFFRLQKLLDELGEKTAIVFVNTKKNCDSIAKNLDKAG 600

  Fly   691 YNSCTLHGGKGQEQREYALAALKSGAKDILVATDVAGRGIDIKDVSLVINYDMAKTIEDYTHRIG 755
            |...||||||.|||||.:|...::...::||||||.||||||.||:.||||||.|.||.||||||
plant   601 YRVTTLHGGKSQEQREISLEGFRAKRYNVLVATDVVGRGIDIPDVAHVINYDMPKHIEMYTHRIG 665

  Fly   756 RTGRAGKTGCAISFVTKDDSALFYDLKQCVSASPVSTCPPELMNHPEAQHKPGTVVTKKRR 816
            |||||||:|.|.||:|..|:.:||||||.:..|. |..||||..|..::.|||||..:..|
plant   666 RTGRAGKSGVATSFLTLHDTEVFYDLKQMLVQSN-SAVPPELARHEASRFKPGTVPDRPPR 725

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10333	NP_609888.2	DEADc	396..629	CDD:238167	143/233 (61%)
		DEXDc	409..632	CDD:214692	140/223 (63%)
		Helicase_C	651..761	CDD:278689	61/109 (56%)
AT2G33730	NP_180929.1	SrmB	286..731	CDD:223587	265/451 (59%)
AT2G33730	NP_180929.1	DEADc_DDX23	324..540	CDD:350703	139/225 (62%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	248	1.000	Domainoid score	I533
eggNOG	1	0.900	-	-		E2759_KOG0333
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H3542
Inparanoid	1	1.050	618	1.000	Inparanoid score	I212
OMA	1	1.010	-	-		QHG55082
OrthoDB	1	1.010	-	-		D820037at2759
OrthoFinder	1	1.000	-	-		FOG0003506
OrthoInspector	1	1.000	-	-		otm3275
orthoMCL	1	0.900	-	-		OOG6_102378
Panther	1	1.100	-	-	LDO	PTHR47958
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3074
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.840