Protein Alignment CG10333 and ddx43

DIOPT Version :10

• Sequence 1: NP_609888.2
• Gene: CG10333 / 35112
• FlyBaseID: FBgn0032690
• Length: 822
• Species: Drosophila melanogaster
• Sequence 2: NP_001072473.1
• Gene: ddx43 / 779928
• XenbaseID: XB-GENE-988016
• Length: 666
• Species: Xenopus tropicalis
• Alignment Length: 699
• Identity: 217/699 - (31%)
• Similarity: 337/699 - (48%)
• Gaps: 146/699 - (20%)

  Fly   132 EELLDKKKREEEARSKPVFL--TKEQRALEAIKRRQEEVERQRAAHDAAREQMAAASKVSISMGT 194
            ||..|....:..||....::  :|:....|...:.|.|....|..:|....:  :.|:.....|.
 Frog     5 EEESDSSSNQAAARYNTPWVPPSKQYSREEPRTKTQSEFCGWREDNDDGGGR--SRSEQGSWRGF 67

  Fly   195 AMASGAPPPAIVAPPPKPDRRERGGGRDR-------------GDRIDRGERGDDKRAEDLTHKDK 246
            :...|:.||.    ....:.|.|.|.||:             |..|.||             ..|
 Frog    68 SRPRGSGPPG----ASTREFRRREGARDQSSPLCFHLDSSAIGQVIGRG-------------GSK 115

  Fly   247 EKELEAIRERYLGIIKKKRRVRRLNDRKFVFDWDAGEDTSIDYNNLYKERHHVQFFGRGNVAGID 311
            .:|||.:....:.|.|                        :||::      .|:.:|.
 Frog   116 IRELEELSGCRIKIEK------------------------LDYDS------EVKIYGN------- 143

  Fly   312 IKEQKRTQSKFYGDLLEKRRT-----------EAEKE-----QEKVRLKKMKRKEDKQKWDDRHW 360
             .||::...:...|::|:...           .|:|.     |.|..:.....:|:|.|::...|
 Frog   144 -SEQQQKAKELIDDIVEQSERGPGFKGFRSSGSADKSADASFQVKPSINWASLRENKSKYEAMKW 207

  Fly   361 SE---------KENDEMT--ERD----WRIFREDYNV---TIKGGR--IPNPIRSWNESGFP-KE 404
            ::         ||:.|:.  .||    ||  :|:.|:   .:|..:  ||||:..:.::..| .|
 Frog   208 ADMPPIAKAFYKESPEVASMSRDEVEKWR--KENNNIICDDLKEEKRSIPNPVPRFEDAFHPFPE 270

  Fly   405 IIDIIDKVGYKEPTPIQRQAIPIGLQNRDIIGVAETGSGKTLAFLIP--LLSWIQSLPKIERLED 467
            ::..::|.|::.|||||.||.|:.||..|:||:|:||:|||||:|:|  :...:|.:|:     :
 Frog   271 VMSALEKSGFERPTPIQSQAWPVILQGIDLIGIAQTGTGKTLAYLLPGFIHLDLQPIPR-----E 330

  Fly   468 VDQGPYAIIMAPTRELAQQIEEETTKFGQPLGIRTVVVVGGLSREEQGFRLRLGCEIVIATPGRL 532
            ...||..:::|||||||.|::.|.:|: :..|..::.:.||..|..|..::..|.:|||||||||
 Frog   331 QQDGPGMLVLAPTRELALQVKAECSKY-KYKGFESICIYGGGDRNNQINKVTKGVDIVIATPGRL 394

  Fly   533 IDVLENRYLVLNQCTYIVLDEADRMIDMGFEPDVQKILEYMPVTNLKPDTEEAEDETKLMENFYT 597
            .|:..|.::.|...||:||||||||:||||||.:.|||     .:::||
 Frog   395 NDLQMNNFVNLKSITYLVLDEADRMLDMGFEPQIMKIL-----IDIRPD---------------- 438

  Fly   598 KKKYRQTVMFTATMPPAVERLARTYLRRPATVYIGSVGKPTERT-EQIVYMMGENDKRKKLMEIL 661
                |.|:|.:||.|..|.|||::||:.|..||:|::......| .|.|.::.|.:||..::..:
 Frog   439 ----RHTIMTSATWPDGVRRLAKSYLKDPMMVYVGTLDLAAVNTVTQHVLVIPEEEKRAFVLHFI 499

  Fly   662 -SRKIDPPVIIFVNQKKGADVLAKGLEKLGYNSCTLHGGKGQEQREYALAALKSGAKDILVATDV 725
             |.|....||:||.:|..||.|:......|....:|||.:.|..||.||...|.|...||||||:
 Frog   500 DSLKPQDKVIVFVGKKLVADDLSSDFSLQGIPVQSLHGNREQCDREQALDDFKKGKVRILVATDL 564

  Fly   726 AGRGIDIKDVSLVINYDMAKTIEDYTHRIGRTGRAGKTGCAISFVTKDD 774
            |.||:|:.||:.|:|:|..:.||:|.||:|||||||:||.:|:.||:.|
 Frog   565 ASRGLDVHDVTHVLNFDFPRNIEEYVHRVGRTGRAGRTGESITLVTRKD 613

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10333	NP_609888.2	DUF5401	<66..354	CDD:375164	45/252 (18%)
		SrmB	395..783	CDD:440279	156/385 (41%)
ddx43	NP_001072473.1	KH-I_DDX43_DDX53	95..160	CDD:411858	17/115 (15%)
		SrmB	269..661	CDD:440279	155/376 (41%)