Protein Alignment CG10333 and Ddx17

DIOPT Version :10

• Sequence 1: NP_609888.2
• Gene: CG10333 / 35112
• FlyBaseID: FBgn0032690
• Length: 822
• Species: Drosophila melanogaster
• Sequence 2: NP_951062.1
• Gene: Ddx17 / 67040
• MGIID: 1914290
• Length: 652
• Species: Mus musculus
• Alignment Length: 447
• Identity: 168/447 - (37%)
• Similarity: 253/447 - (56%)
• Gaps: 51/447 - (11%)

  Fly   352 KQKWD---------DRHWSEKENDEMTERDWRIFREDYNVTIKGGRI-PNPIRSWNESGFPKEII 406
            |:|||         :.:....|...:|..:....|....:|::||.: |.|:.:::.:.||:.::
Mouse    40 KKKWDLSELPKFEKNFYVEHPEVARLTPYEVDELRRKKEITVRGGDVCPKPVFAFHHANFPQYVM 104

  Fly   407 DIIDKVGYKEPTPIQRQAIPIGLQNRDIIGVAETGSGKTLAFLIPLLSWIQSLPKIERLEDVDQG 471
            |::....:.||||||.|..|:.|..||::|:|:||||||||:|:|.:..|...|.:||    ..|
Mouse   105 DVLMDQHFTEPTPIQCQGFPLALSGRDMVGIAQTGSGKTLAYLLPAIVHINHQPYLER----GDG 165

  Fly   472 PYAIIMAPTRELAQQIEEETTKFGQPLGIRTVVVVGGLSREEQGFRLRLGCEIVIATPGRLIDVL 536
            |..:::|||||||||:::....:|:...:::..:.||..:..|...|..|.||.|||||||||.|
Mouse   166 PICLVLAPTRELAQQVQQVADDYGKCSRLKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFL 230

  Fly   537 ENRYLVLNQCTYIVLDEADRMIDMGFEPDVQKILEYMPVTNLKPDTEEAEDETKLMENFYTKKKY 601
            |:....|.:|||:||||||||:||||||.::||     |..::||
Mouse   231 ESGKTNLRRCTYLVLDEADRMLDMGFEPQIRKI-----VDQIRPD-------------------- 270

  Fly   602 RQTVMFTATMPPAVERLARTYLRRPATVYIGSVG-KPTERTEQIVYMMGENDKRKKLM----EIL 661
            |||:|::||.|..|.:||..:||....:.:|::. .......|||.:..|::|..||:    ||:
Mouse   271 RQTLMWSATWPKEVRQLAEDFLRDYTQINVGNLELSANHNILQIVDVCMESEKDHKLIQLMEEIM 335

  Fly   662 SRKIDPPVIIFVNQKKGADVLAKGLEKLGYNSCTLHGGKGQEQREYALAALKSGAKDILVATDVA 726
            :.| :...||||..|:..|.|.:.:.:.|:.:..:||.|.|.:|::.|...:||...||:|||||
Mouse   336 AEK-ENKTIIFVETKRRCDDLTRRMRRDGWPAMCIHGDKSQPERDWVLNEFRSGKAPILIATDVA 399

  Fly   727 GRGIDIKDVSLVINYDMAKTIEDYTHRIGRTGRAGKTGCAISFVTKDDSALFYDLKQ 783
            .||:|::||..|||||...:.|||.||||||.|:...|.|.:|.|..      :|||
Mouse   400 SRGLDVEDVKFVINYDYPNSSEDYVHRIGRTARSTNKGTAYTFFTPG------NLKQ 450

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10333	NP_609888.2	DUF5401	<66..354	CDD:375164	1/1 (100%)
		SrmB	395..783	CDD:440279	154/392 (39%)
Ddx17	NP_951062.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..38
		DEAD-like_helicase_N	32..502	CDD:475120	168/447 (38%)
		Q motif	92..120		8/27 (30%)
		DEAD box	246..249		2/2 (100%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	585..652
		Interaction with YAP1. /evidence=ECO:0000250|UniProtKB:Q92841	641..649