DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10333 and CG9630

DIOPT Version :9

Sequence 1:	NP_609888.2	Gene:	CG10333 / 35112	FlyBaseID:	FBgn0032690	Length:	822	Species:	Drosophila melanogaster
Sequence 2:	NP_649777.1	Gene:	CG9630 / 40974	FlyBaseID:	FBgn0037561	Length:	613	Species:	Drosophila melanogaster

Alignment Length:	413	Identity:	126/413 - (30%)
Similarity:	201/413 - (48%)	Gaps:	57/413 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   394 RSWNESGFP---KEIIDIIDKVGYKEPTPIQRQAIPIGLQNRDIIGVAETGSGKTLAFLIPLLSW 455
            :.|:....|   ..::.::...|:::.||:|..|||:.|..:|:...|.||||||||||:|:|..
  Fly     4 KKWSSLDKPPLSDAVLQVVQSFGFQQMTPVQTAAIPLLLARKDVSAEAVTGSGKTLAFLVPMLEI 68

  Fly   456 IQSLPKIERLEDVDQGPY---AIIMAPTRELAQQIEEETTKFGQPLGIRTV---VVVGGLSREEQ 514
            :|     .|.::...||.   |::::||||||:||.|...:|.:...:..:   ::|||.|.||.
  Fly    69 LQ-----RRHKETPWGPKEIGALVISPTRELARQISEVLAQFLEHEDLEHLNQQLIVGGNSIEED 128

  Fly   515 GFRLR--LGCEIVIATPGRLIDVLENRYLVLN------QCTYIVLDEADRMIDMGFEPDVQKILE 571
            ...||  ..| |::.|||||.|:.:.:...||      ...::|||||||::|:||:..|..||.
  Fly   129 IATLRRETPC-ILVCTPGRLEDLFQRKGDDLNLAAQVKSLEFLVLDEADRLLDLGFKTSVNNILG 192

  Fly   572 YMPVTNLKPDTEEAEDETKLMENFYTKKKYRQTVMFTATMPPAVERLARTYLRRPATVYI---GS 633
            |:|                         :.|:|.:|:||....|..|.|..||.|..|.:   .|
  Fly   193 YLP-------------------------RQRRTGLFSATQTTEVTDLIRAGLRNPVLVSVKEKAS 232

  Fly   634 VGKPTERTEQIVYMMGENDKRKKLMEILS--RKIDPPVIIFVNQKKGADVLAKGLEKLGYNSCTL 696
            |..|. |.:....::....|...|:|.||  ..:...|::|.......:..|:.|..|......|
  Fly   233 VNTPA-RLQNFYRIVEPELKFVALLEFLSSPATVIGKVMVFFPTCACVEYWAEALPPLLPKRTVL 296

  Fly   697 --HGGKGQEQREYALAALKSGAKDILVATDVAGRGIDIKDVSLVINYDMAKTIEDYTHRIGRTGR 759
              | ||.:.:|...:...::..:.:|:.|||..||:|:.::..|:.:|...|...:.||:|||.|
  Fly   297 GIH-GKMKNKRANVVEKFRNTPQAVLLCTDVLARGLDVPEIEWVVQWDPPSTASSFVHRVGRTAR 360

  Fly   760 AGKTGCAISFVTKDDSALFYDLK 782
            .|..|.|:.|:...:.|..:.||
  Fly   361 QGNEGNALVFLLPSEDAYVHFLK 383

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10333	NP_609888.2	DEADc	396..629	CDD:238167	83/249 (33%)
		DEXDc	409..632	CDD:214692	82/239 (34%)
		Helicase_C	651..761	CDD:278689	31/113 (27%)
CG9630	NP_649777.1	DEADc	6..226	CDD:238167	83/250 (33%)
		DEXDc	22..232	CDD:214692	82/240 (34%)
		HELICc	239..370	CDD:238034	34/131 (26%)
		DUF4217	411..470	CDD:290667
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45451682
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840