DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG10333 and eIF4A

DIOPT Version :9

Sequence 1:NP_609888.2 Gene:CG10333 / 35112 FlyBaseID:FBgn0032690 Length:822 Species:Drosophila melanogaster
Sequence 2:NP_001245907.1 Gene:eIF4A / 33835 FlyBaseID:FBgn0001942 Length:403 Species:Drosophila melanogaster


Alignment Length:435 Identity:130/435 - (29%)
Similarity:215/435 - (49%) Gaps:57/435 - (13%)


- Green bases have known domain annotations that are detailed below.


  Fly   356 DDRHW------SEKENDEMTERDWRIFREDYNVTIKGGRIPNPIRSWNESGFPKEIIDIIDKVGY 414
            |||:.      :..|.:.:.|..|   .|.|:             ::::....:|::..|...|:
  Fly     2 DDRNEIPQDGPASMEPEGVIESTW---HEVYD-------------NFDDMNLREELLRGIYGYGF 50

  Fly   415 KEPTPIQRQAIPIGLQNRDIIGVAETGSGKTLAFLIPLLSWIQSLPKIERLEDVDQGPYAIIMAP 479
            ::|:.||::||...::.||:|..|::|:|||..|.|.:|..|.:  .|...:       |:|:||
  Fly    51 EKPSAIQQRAIIPCVRGRDVIAQAQSGTGKTATFSIAILQQIDT--SIRECQ-------ALILAP 106

  Fly   480 TRELAQQIEEETTKFGQPLGIRTVVVVGGLSREEQGFRLRLGCEIVIATPGRLIDVLENRYLVLN 544
            |||||.||:......|:.:.:.:...:||.:..|....|..||.:|:.||||:.|::..:.|...
  Fly   107 TRELATQIQRVVMALGEYMKVHSHACIGGTNVREDARILESGCHVVVGTPGRVYDMINRKVLRTQ 171

  Fly   545 QCTYIVLDEADRMIDMGFEPDVQKILEYMPVTNLKPDTEEAEDETKLMENFYTKKKYRQTVMFTA 609
            .....||||||.|:..||:..:|.:.:.:|     ||.                    |.::.:|
  Fly   172 YIKLFVLDEADEMLSRGFKDQIQDVFKMLP-----PDV--------------------QVILLSA 211

  Fly   610 TMPPAVERLARTYLRRPATVYIGSVGKPTERTEQI-VYMMGENDKRKKLMEILSRKIDPPVIIFV 673
            ||||.|..::|.::|.|.::.:.......|..:|. |.:..||.|...|.::.........:||.
  Fly   212 TMPPDVLEVSRCFMRDPVSILVKKEELTLEGIKQFYVNVKQENWKLGTLCDLYDTLSITQSVIFC 276

  Fly   674 NQKKGADVLAKGLEKLGYNSCTLHGGKGQEQREYALAALKSGAKDILVATDVAGRGIDIKDVSLV 738
            |.::..|.|.:.:....:....:||...|..||..:...:||:..:|:.||:..||||::.||||
  Fly   277 NTRRKVDQLTQEMSIHNFTVSAMHGDMEQRDREVIMKQFRSGSSRVLITTDLLARGIDVQQVSLV 341

  Fly   739 INYDMAKTIEDYTHRIGRTGRAGKTGCAISFVTKDDSALFYDLKQ 783
            ||||:....|:|.|||||.||.|:.|.||:|:|.||..:..|::|
  Fly   342 INYDLPSNRENYIHRIGRGGRFGRKGVAINFITDDDRRILKDIEQ 386

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG10333NP_609888.2 DEADc 396..629 CDD:238167 69/232 (30%)
DEXDc 409..632 CDD:214692 68/222 (31%)
Helicase_C 651..761 CDD:278689 39/109 (36%)
eIF4ANP_001245907.1 PTZ00424 6..403 CDD:185609 127/431 (29%)
DEADc 32..232 CDD:238167 69/233 (30%)
Helicase_C 254..358 CDD:278689 34/103 (33%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C45451796
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
21.840

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