Protein Alignment CG10333 and ddx46

DIOPT Version :10

• Sequence 1: NP_609888.2
• Gene: CG10333 / 35112
• FlyBaseID: FBgn0032690
• Length: 822
• Species: Drosophila melanogaster
• Sequence 2: NP_001019988.2
• Gene: ddx46 / 321948
• ZFINID: ZDB-GENE-030131-667
• Length: 1035
• Species: Danio rerio
• Alignment Length: 855
• Identity: 272/855 - (31%)
• Similarity: 402/855 - (47%)
• Gaps: 173/855 - (20%)

  Fly     5 KKRRSRSRERHREDRPAVGNPRDRERERDRVRERDRQFDREKERRQRRSRSREDRNRRRSPERQR 69
            |.|...|:...::||.|......|||.|.|.|.|.|:       |:|:.||..||.|.||.||:|
Zfish    23 KSRSPDSKRSKKDDRTASRTHSRRERSRSRERRRSRE-------RKRQRRSSRDRRRSRSRERRR 80

  Fly    70 PRDNVRERSRERGGGAGGGGGGGAEKKAKMDTGD-APPKPLIVDDEEQQDGKEAKVKKEPLSLEE 133
            .:...|.||:|                 |.:.|| ...|..|.:::|::..::....:..|. ||
Zfish    81 SKSRSRGRSKE-----------------KPENGDQTADKKKIKEEKEEEKPEDQDFDQNTLE-EE 127

  Fly   134 LLDKKKREEEARSKPVFLTKEQRALEAIKRRQEEVERQRAAHDAAREQMAAASKVSISMGTAMAS 198
            :..:|:|.|:.|.:     :.::|:|.|...::|:           |:|....|.|:........
Zfish   128 MRKRKERVEKWREE-----QRKKAMENIGEIKKEL-----------EEMKQGKKWSLEDDDDDDE 176

  Fly   199 GAPPPAIVAPPPKPDRRERGGGRDRGDRIDRGERGDDKRAEDLTHKDKEKELEAIRERYLGIIKK 263
            .||.|.      :||                   |||:..:|...:.:|.|
Zfish   177 EAPAPV------EPD-------------------GDDEEEQDKAAEAEESE-------------- 202

  Fly   264 KRRVRRLNDRKFVFDWDAGEDTSIDYNNLYKE--RHHVQFFGRGNVAGID--------------I 312
                 |:.:.      :.||:  :|..:.|.|  :..|:.|..|.:.|.:              :
Zfish   203 -----RMEEE------EVGEE--VDPLDAYMEEVKEEVKKFNMGTMKGANDKKGGMSVTKVVTVV 254

  Fly   313 KEQKRTQ-SKFYGDLLEKRR--TEAEKEQEKVRL-----------KKMKRKEDKQKWDDRHWSEK 363
            |.:|... :|..|:|:|..:  .|...|:|:|.|           :|:....|.||.....:.:.
Zfish   255 KTKKMPHATKKKGELMENDQDAMEYSSEEEEVDLQTALTGFQTKQRKVLEPVDHQKIQYEPFRKN 319

  Fly   364 ENDEMTE---------RDWRIFREDYNVTIKGGRIPNPIRSWNESGFPKEIIDIIDKVGYKEPTP 419
            ...|:.|         .::|:..|  .:::||...|.||::|.:.|...::::.:.|..|::|||
Zfish   320 FYVEVPELARMSPEEVSEYRLELE--GISVKGKGCPKPIKTWVQCGISMKVLNALKKHNYEKPTP 382

  Fly   420 IQRQAIPIGLQNRDIIGVAETGSGKTLAFLIPLLSWIQSLPKIERLEDVDQGPYAIIMAPTRELA 484
            ||.||||..:..||:||:|:||||||:|||:|:...|.....:...|    ||.|:||.||||||
Zfish   383 IQAQAIPAIMSGRDLIGIAKTGSGKTIAFLLPMFRHILDQRPVGEAE----GPLAVIMTPTRELA 443

  Fly   485 QQIEEETTKFGQPLGIRTVVVVGGLSREEQGFRLRLGCEIVIATPGRLIDVL---ENRYLVLNQC 546
            .||.:|..||.:.|.:|.|.|.||....||...|:.|.||::.||||:||:|   ..|...|.:.
Zfish   444 LQITKECKKFSKSLALRVVCVYGGTGISEQIAELKRGAEIIVCTPGRMIDMLGANNGRVTNLRRV 508

  Fly   547 TYIVLDEADRMIDMGFEPDVQKILEYMPVTNLKPDTEEAEDETKLMENFYTKKKYRQTVMFTATM 611
            ||:|:||||||.||||||.|.:|     |.|::||                    ||||||:||.
Zfish   509 TYVVIDEADRMFDMGFEPQVMRI-----VDNVRPD--------------------RQTVMFSATF 548

  Fly   612 PPAVERLARTYLRRPATVYIGSVGKPTERTEQIVYMMGENDKRKKLMEILSRKIDP-PVIIFVNQ 675
            |..:|.|||..|.:|..|.:|.........||.|.::.|..|..||:|||....:. .|||||::
Zfish   549 PRTMEALARRILSKPVEVQVGGRSVVCSDVEQHVIVIEEEKKFLKLLEILGHYQEKGSVIIFVDK 613

  Fly   676 KKGADVLAKGLEKLGYNSCTLHGGKGQEQREYALAALKSGAKDILVATDVAGRGIDIKDVSLVIN 740
            ::.||.|.|.|.|..|...:||||..|..|:..:...|:||..:||||.||.||:|:|.:.||:|
Zfish   614 QEHADGLLKDLMKASYPCMSLHGGIDQYDRDSIINDFKNGACRLLVATSVAARGLDVKQLILVVN 678

  Fly   741 YDMAKTIEDYTHRIGRTGRAGKTGCAISFVTKDDSALFYDLKQCVSASPVSTCPPEL----MNHP 801
            |......|||.||.|||||||..|.|.:|:|:..:....|:.:.:..|. |:.|.||    .|..
Zfish   679 YSCPNHYEDYVHRAGRTGRAGNKGYAYTFITEGQARYSGDILKALELSG-SSVPAELEQLWTNFK 742

  Fly   802 EAQHKPGTVV 811
            |.|...|.::
Zfish   743 EQQKAEGKII 752

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10333	NP_609888.2	DUF5401	<66..354	CDD:375164	62/318 (19%)
		SrmB	395..783	CDD:440279	167/391 (43%)
ddx46	NP_001019988.2	Q motif	357..385		8/27 (30%)
		DEAD box	514..517		2/2 (100%)