Protein Alignment CG10333 and CG14443

DIOPT Version :10

• Sequence 1: NP_609888.2
• Gene: CG10333 / 35112
• FlyBaseID: FBgn0032690
• Length: 822
• Species: Drosophila melanogaster
• Sequence 2: NP_572330.2
• Gene: CG14443 / 31595
• FlyBaseID: FBgn0029880
• Length: 736
• Species: Drosophila melanogaster
• Alignment Length: 879
• Identity: 179/879 - (20%)
• Similarity: 323/879 - (36%)
• Gaps: 248/879 - (28%)

  Fly    22 VGNPRDRERERDRVRER------------DRQFDREKERRQRRSRSREDRNR---------RRSP 65
            :||.:|.|.:.::|:::            ....|...:.|..:|.|....::         :...
  Fly    10 IGNWKDNETDAEKVQKKPFLKGTKSSIWGSSASDISGQSRSLKSSSSVLSSKFVTKRLFTIQHGI 74

  Fly    66 ERQRPRDNVRERSRERGGGAGGGGGGGAEKKAKMDTGDAPPKPLIVDDEEQQDGKEAKVKKEPLS 130
            |.|:|...:|..|......|||
  Fly    75 EGQKPNFKIRSESFSGPHSAGG------------------------------------------- 96

  Fly   131 LEELLDKKKREEEARSKPVFLTKEQRALEAIKRRQEEVERQRAAHDAAREQMAAASKVSISMGTA 195
                ..|..||..::|:.:...| .|....::...|      :||.:..|..::.|....|..:.
  Fly    97 ----FSKSTRESRSKSRSMGNGK-FRGKSHLRSSSE------SAHSSGSESSSSDSNSGSSSDSD 150

  Fly   196 MASGA-------------------------PPPAIVAPPPKPDRRERGGGRDRGDRIDRGERGDD 235
            ..:|:                         .|.:..|.....:.:|   .|.|...:.:......
  Fly   151 STTGSSSHGSDTGERPRMRSAVFRIHETWQSPNSFKAVKTSRENKE---SRSRSSSLPQKRFCPS 212

  Fly   236 KRAEDLTHKDKEKELEAIRERYLGIIKKKRRVRRLNDRKFVFDWDAGEDTSIDYNNLYKERHHVQ 300
            |...|||:...|.:..:.|.|.                    .|..|..|.      :|
  Fly   213 KTQNDLTYGSPEPKSPSNRGRN--------------------SWRVGMRTP------WK------ 245

  Fly   301 FFGRGNVAGIDIKEQKRTQS-----------KFYGDLLEKRRTEAEKEQEKVRLKKMKRKEDKQK 354
                        |.|.|:.|           .|.......|.|...::|.    |...|..:...
  Fly   246 ------------KSQSRSMSCSSIQKILVSRSFTRSRSPHRNTLCYQDQS----KNPSRPSNYNT 294

  Fly   355 WD---DRHWSEKENDEMTERDWRIFREDYNVTIKG---GRIPNPIRSWNESGFPKEIIDIIDKVG 413
            |.   |..::...|          :|:.:|:|:..   ..:|.|:.|:..|||...|:..::..|
  Fly   295 WKQPMDEVYNNAAN----------YRKRHNITLTSWNMRNLPEPVLSFERSGFNATILQQLEDQG 349

  Fly   414 YKEPTPIQRQAIPIGLQNRDIIGVAETGSGKTLAFLIPLLSWIQSLPKIERLEDVDQGPYAIIMA 478
            |..|||||.|...|..:.::|:.::..|:||||.:|:|   .|..:.....|....:||..:|:.
  Fly   350 YDGPTPIQAQTWSIAKEGKNIVMISGKGTGKTLGYLLP---GIMKMHNQRGLMQHKKGPIVLILV 411

  Fly   479 PTRELAQQIEEETTKFGQPLGIRTVVVVGGLSREEQGFRLRLGCEIVIATPGRLIDVLENRYLV- 542
            ..||.|..::.|...:..||.:||..::|  :.:.||   ...|::::|:.|||:.:::|:..|
  Fly   412 DCREAAVMVQREVLYYTNPLELRTHCLLG--NSQWQG---HAECDLLVASAGRLLQMIDNKKHVV 471

  Fly   543 -LNQCTYIVLDEADRMIDMGFEPDVQKILEYMPVTNLKPDTEEAEDETKLMENFYTKKKYRQTVM 606
             |.:|||:|||..|||||:|.|.::.::|     ..|:|                    :.|.::
  Fly   472 ELERCTYLVLDNIDRMIDVGLEGNICRLL-----CRLRP--------------------HAQLIV 511

  Fly   607 FTATMPPAVERLARTYLRRPATVYIG---SVGKPTERTEQIVYMMGENDKRKKLMEILSRKIDP- 667
            .:.:....::|:|..:|.:...:.:|   ::|...:...|.|.::....|.::||:.|:...|.
  Fly   512 SSTSWSSNLKRMANKFLGQYTAIRVGEINNIGVRLQNIRQRVEVVNGLSKVERLMKELTAIYDTS 576

  Fly   668 ----PVIIFVNQKKGADVLAKGLEKLGYNSCT----LHGGKGQEQREYALAALKSGAKDILVATD 724
                .|:|:|.::|..:.|...:     .:|.    :|||:..::.:..:....:||.:|:|||.
  Fly   577 DIPGKVVIYVKRQKVVEELVDLI-----RNCVPCEGIHGGRTAQENQGIIHDFGTGAYNIIVATQ 636

  Fly   725 VAGRGIDIKDVSLVINYDMAKTIEDYTHRIGRTG-RAGKTGC-AISFVTKDDSALFYDLKQCVSA 787
            :....:|:..:..|||||....|:.|..|:.||| .:....| .|||.|..:..|..::     .
  Fly   637 MTSNCLDVPGIRYVINYDFPDNIDKYVQRMSRTGCLSYNRNCEVISFFTMANYKLVTEV-----V 696

  Fly   788 SPVSTCPPELMNHPEAQHKPGTVVTKKRREEKIF 821
            ..:..|..|:..|           ..:..|||:|
  Fly   697 DFLKICKQEIGPH-----------LLQLAEEKMF 719

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10333	NP_609888.2	DUF5401	<66..354	CDD:375164	47/323 (15%)
		SrmB	395..783	CDD:440279	108/403 (27%)
CG14443	NP_572330.2	DEAD-like_helicase_N	<310..720	CDD:475120	120/464 (26%)