Protein Alignment CG10333 and Ddx41

DIOPT Version :10

• Sequence 1: NP_609888.2
• Gene: CG10333 / 35112
• FlyBaseID: FBgn0032690
• Length: 822
• Species: Drosophila melanogaster
• Sequence 2: NP_001101516.1
• Gene: Ddx41 / 314336
• RGDID: 1311758
• Length: 622
• Species: Rattus norvegicus
• Alignment Length: 612
• Identity: 207/612 - (33%)
• Similarity: 319/612 - (52%)
• Gaps: 107/612 - (17%)

  Fly   211 KPDRRERGGGRDRGDRIDRGERGDDKRAEDLTHKDKEKE-------LEAIRERYLGIIKKKRRVR 268
            :|:|:     |.|.:....|    ..|:||   :|::.|       |...|:..|..:.::||..
  Rat     5 EPERK-----RARTNEATAG----GSRSED---EDEDDEDYVPYVPLRQRRQLLLQKLLQRRRKG 57

  Fly   269 RLNDRKFVFDWDAGEDTSIDYNNLYKERHHVQFFGRGNVAGID----IKEQKRTQSKFYGDLLEK 329
            ...:.:    .|:|.:...|.::       :....:.||:.:|    :||:...:.:   ...||
  Rat    58 AAEEEQ----QDSGSEPRGDEDD-------IPLGPQSNVSLLDQHQHLKEKAEARKE---SAKEK 108

  Fly   330 RRTEAEKEQEKV-------RLKKMKR---KED--KQKWDDRHWSEKENDEMTERDWRIFREDYNV 382
            :..|.||..|.|       .:|:|.:   .:|  |..|....:....::|..||    .|:.|::
  Rat   109 QLKEEEKILESVAEGRALMSVKEMAKGITYDDPIKTSWTPPRYVLSMSEERHER----VRKKYHI 169

  Fly   383 TIKGGRIPNPIRSWNESGFPKEIIDIIDKVGYKEPTPIQRQAIPIGLQNRDIIGVAETGSGKTLA 447
            .::|..||.||:|:.|...|..|:..:.|.|...|||||.|.||..|..||:||:|.|||||||.
  Rat   170 LVEGDGIPPPIKSFKEMKLPAAILRGLKKKGILHPTPIQIQGIPTILSGRDMIGIAFTGSGKTLV 234

  Fly   448 FLIPLLSWI----QSLPKIERLEDVDQGPYAIIMAPTRELAQQ-----------IEEETTKFGQP 497
            |.:|::.:.    :.||..:|     :|||.:|:.|:||||:|           ::|:::    |
  Rat   235 FTLPVIMFCLEQEKRLPFSKR-----EGPYGLIICPSRELARQTHGILEYYCRLLQEDSS----P 290

  Fly   498 LGIRTVVVVGGLSREEQGFRLRLGCEIVIATPGRLIDVLENRYLVLNQCTYIVLDEADRMIDMGF 562
            | :|..:.:||:|.:||...:|.|..:::||||||:|:|:.:.:.|:.|.|:.||||||||||||
  Rat   291 L-LRCALCIGGMSVKEQMETIRHGVHMMVATPGRLMDLLQKKMVSLDICRYLALDEADRMIDMGF 354

  Fly   563 EPDVQKILEYMPVTNLKPDTEEAEDETKLMENFYTKKKYRQTVMFTATMPPAVERLARTYLRRPA 627
            |.|::.|..|.                         |..|||::|:||||..::..|::.|.:|.
  Rat   355 EGDIRTIFSYF-------------------------KGQRQTLLFSATMPKKIQNFAKSALVKPV 394

  Fly   628 TVYIGSVGKPTERTEQIVYMMGENDKRKKLMEILSRKIDPPVIIFVNQKKGADVLAKGLEKLGYN 692
            |:.:|..|..:....|.|..:.|..|...|:|.| :|..|||:||..:|...|.:.:.|...|..
  Rat   395 TINVGRAGAASLDVIQEVEYVKEEAKMVYLLECL-QKTPPPVLIFAEKKADVDAIHEYLLLKGVE 458

  Fly   693 SCTLHGGKGQEQREYALAALKSGAKDILVATDVAGRGIDIKDVSLVINYDMAKTIEDYTHRIGRT 757
            :..:||||.||:|..|:.|.:.|.||:|||||||.:|:|...:..||||||.:.||:|.||||||
  Rat   459 AVAIHGGKDQEERTKAIEAFREGKKDVLVATDVASKGLDFPAIQHVINYDMPEEIENYVHRIGRT 523

  Fly   758 GRAGKTGCAISFVTK--DDSALFYDLK 782
            ||:|.||.|.:|:.|  |:|.|. |||
  Rat   524 GRSGNTGIATTFINKACDESVLM-DLK 549

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10333	NP_609888.2	DUF5401	<66..354	CDD:375164	34/165 (21%)
		SrmB	395..783	CDD:440279	162/405 (40%)
Ddx41	NP_001101516.1	SrmB	180..562	CDD:440279	163/407 (40%)