Protein Alignment CG10333 and Ddx42

DIOPT Version :10

• Sequence 1: NP_609888.2
• Gene: CG10333 / 35112
• FlyBaseID: FBgn0032690
• Length: 822
• Species: Drosophila melanogaster
• Sequence 2: NP_001100529.1
• Gene: Ddx42 / 303607
• RGDID: 1304909
• Length: 929
• Species: Rattus norvegicus
• Alignment Length: 658
• Identity: 210/658 - (31%)
• Similarity: 313/658 - (47%)
• Gaps: 109/658 - (16%)

  Fly   164 RQEEVERQRAAHDAAREQMAAASKVSISMGTAMASGAPPPAIVAPPPKPDRRERGGGRDRGDRID 228
            ::||.:..:.:|.|    ..|||. |...|.:           |||..|...:.|..|...|.
  Rat    25 KKEEAKLPQQSHSA----FGAASS-SSGFGKS-----------APPQLPSFYKIGSKRANFDE-- 71

  Fly   229 RGERGDDKRAEDLTHKDKEKELEAIRERYLGIIKKKRRVRRLNDRKFVFDWDAGED--------- 284
                      |:...:|:|::...:...|   |..:....|...|....|.|:.:|
  Rat    72 ----------ENAYFEDEEEDSSNVDLPY---IPAENSPTRQQFRSKPADSDSDDDPLEAFMAEV 123

  Fly   285 ---TSIDYNNLYKERHHVQFFGRGNVAGI--DIKEQKRTQSKFYGDLLEKRRTEAEKEQEKVRL- 343
               .:.|...|.::...     |.||.||  ||:|:. .|..::..:.|.......:|:|:..|
  Rat   124 EDQAARDMKRLEEKDKE-----RKNVKGIRDDIEEED-DQEAYFRYMAENPTAGVVQEEEEDNLE 182

  Fly   344 -----------KKM--------KRKEDKQKWDDRHWSEKEN-DEMTERDWRIFREDYNVTIKGGR 388
                       ||:        ..:.|...::...::|.|. ..:|.:.....|...|:.:.|..
  Rat   183 YDSDGNPIAPSKKIIDPLPPIDHSEIDYPPFEKNFYNEHEEITNLTPQQLIDLRHKLNLRVSGAA 247

  Fly   389 IPNPIRSWNESGFPKEIIDIIDKVGYKEPTPIQRQAIPIGLQNRDIIGVAETGSGKTLAFLIPLL 453
            .|.|..|:...||.::::..|.|..|.:|||||.|.:|:.|..||:||:|:||||||.||:.|:|
  Rat   248 PPRPGSSFAHFGFDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTGSGKTAAFIWPML 312

  Fly   454 SWIQSLPKIERLEDVDQGPYAIIMAPTRELAQQIEEETTKFGQPLGIRTVVVVGGLSREEQGFRL 518
            ..|....::|    ...||.|:|:.|||||.|||..|..:||:...:|:|.|.||.|..||...|
  Rat   313 IHIMDQKELE----PGDGPIAVIVCPTRELCQQIHAECKRFGKAYNLRSVAVYGGGSMWEQAKAL 373

  Fly   519 RLGCEIVIATPGRLIDVLENRYLVLNQCTYIVLDEADRMIDMGFEPDVQKILEYMPVTNLKPDTE 583
            :.|.|||:.|||||||.::.:...|.:.:|:|.||||||.|||||..|:.|     .::::||
  Rat   374 QEGAEIVVCTPGRLIDHVKKKATNLQRVSYLVFDEADRMFDMGFEYQVRSI-----ASHVRPD-- 431

  Fly   584 EAEDETKLMENFYTKKKYRQTVMFTATMPPAVERLARTYLRRPATVYIGSVGKPTERTEQIVYMM 648
                              |||::|:||....:|:|||..|..|..|..|.:|:..|...|||.::
  Rat   432 ------------------RQTLLFSATFRKKIEKLARDILIDPIRVVQGDIGEANEDVTQIVEIL 478

  Fly   649 GENDKR-----KKLMEILSRKIDPPVIIFVNQKKGADVLAKGLEKLGYNSCTLHGGKGQEQREYA 708
            .....:     ::|:|..|   ...|::||.:|..|:.||..|::.|:|...|||...|.:|...
  Rat   479 HSGPSKWNWLTRRLVEFTS---SGSVLLFVTKKANAEELANNLKQEGHNLGLLHGDMDQSERNKV 540

  Fly   709 LAALKSGAKDILVATDVAGRGIDIKDVSLVINYDMAKTIEDYTHRIGRTGRAGKTGCAISFVTKD 773
            :...|.....:|||||||.||:||..:..|||||:|:.|:.:|||||||||||:.|.|.:.:|..
  Rat   541 ILDFKKKDIPVLVATDVAARGLDIPSIKTVINYDVARDIDTHTHRIGRTGRAGEKGVAYTLLTPK 605

  Fly   774 DSALFYDL 781
            ||....||
  Rat   606 DSNFAGDL 613

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10333	NP_609888.2	DUF5401	<66..354	CDD:375164	44/223 (20%)
		SrmB	395..783	CDD:440279	158/392 (40%)
Ddx42	NP_001100529.1	SrmB	254..677	CDD:440279	158/392 (40%)
		dermokine	<644..>889	CDD:455732