DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG10333 and Ddx5

DIOPT Version :10

Sequence 1:NP_609888.2 Gene:CG10333 / 35112 FlyBaseID:FBgn0032690 Length:822 Species:Drosophila melanogaster
Sequence 2:NP_001007614.1 Gene:Ddx5 / 287765 RGDID:619906 Length:615 Species:Rattus norvegicus


Alignment Length:444 Identity:164/444 - (36%)
Similarity:254/444 - (57%) Gaps:44/444 - (9%)


- Green bases have known domain annotations that are detailed below.


  Fly   352 KQKWD-------DRHWSEKEND--EMTERDWRIFREDYNVTIKGGRIPNPIRSWNESGFPKEIID 407
            |:||:       ::::.::..|  ..|.::...:|....:|::|...|.|:.::.|:.||..::|
  Rat    43 KKKWNLDELPKFEKNFYQEHPDLARRTAQEVDTYRRSKEITVRGHNCPKPVLNFYEANFPANVMD 107

  Fly   408 IIDKVGYKEPTPIQRQAIPIGLQNRDIIGVAETGSGKTLAFLIPLLSWIQSLPKIERLEDVDQGP 472
            :|.:..:.|||.||.|..|:.|...|::|||:|||||||::|:|.:..|...|.:||    ..||
  Rat   108 VIARQNFTEPTAIQAQGWPVALSGLDMVGVAQTGSGKTLSYLLPAIVHINHQPFLER----GDGP 168

  Fly   473 YAIIMAPTRELAQQIEEETTKFGQPLGIRTVVVVGGLSREEQGFRLRLGCEIVIATPGRLIDVLE 537
            ..:::|||||||||:::...::.:...:::..:.||..:..|...|..|.||.|||||||||.||
  Rat   169 ICLVLAPTRELAQQVQQVAAEYCRACRLKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLE 233

  Fly   538 NRYLVLNQCTYIVLDEADRMIDMGFEPDVQKILEYMPVTNLKPDTEEAEDETKLMENFYTKKKYR 602
            .....|.:.||:||||||||:||||||.::||     |..::||                    |
  Rat   234 CGKTNLRRTTYLVLDEADRMLDMGFEPQIRKI-----VDQIRPD--------------------R 273

  Fly   603 QTVMFTATMPPAVERLARTYLRRPATVYIGSVG-KPTERTEQIVYMMGENDKRKKLM----EILS 662
            ||:|::||.|..|.:||..:|:....:.||::. .......|||.:..:.:|.:||:    ||:|
  Rat   274 QTLMWSATWPKEVRQLAEDFLKDYIHINIGALELSANHNILQIVDVCHDVEKDEKLIRLMEEIMS 338

  Fly   663 RKIDPPVIIFVNQKKGADVLAKGLEKLGYNSCTLHGGKGQEQREYALAALKSGAKDILVATDVAG 727
            .| :...|:||..|:..|.|.:.:.:.|:.:..:||.|.|::|::.|...|.|...||:|||||.
  Rat   339 EK-ENKTIVFVETKRRCDELTRKMRRDGWPAMGIHGDKSQQERDWVLNEFKHGKAPILIATDVAS 402

  Fly   728 RGIDIKDVSLVINYDMAKTIEDYTHRIGRTGRAGKTGCAISFVTKDDSALFYDL 781
            ||:|::||..|||||...:.|||.||||||.|:.|||.|.:|.|.::.....||
  Rat   403 RGLDVEDVKFVINYDYPNSSEDYIHRIGRTARSTKTGTAYTFFTPNNIKQVSDL 456

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG10333NP_609888.2 DUF5401 <66..354 CDD:375164 1/1 (100%)
SrmB 395..783 CDD:440279 154/392 (39%)
Ddx5NP_001007614.1 DEAD-like_helicase_N 6..507 CDD:475120 164/444 (37%)
P68HR 498..532 CDD:429808
P68HR 551..583 CDD:429808
Blue background indicates that the domain is not in the aligned region.

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