Protein Alignment CG10333 and Ddx46

DIOPT Version :10

• Sequence 1: NP_609888.2
• Gene: CG10333 / 35112
• FlyBaseID: FBgn0032690
• Length: 822
• Species: Drosophila melanogaster
• Sequence 2: NP_620798.1
• Gene: Ddx46 / 245957
• RGDID: 708480
• Length: 1032
• Species: Rattus norvegicus
• Alignment Length: 852
• Identity: 284/852 - (33%)
• Similarity: 418/852 - (49%)
• Gaps: 147/852 - (17%)

  Fly     6 KRRSRS----RERHREDRPAVGNPRDRERERDRVRERDRQFDREKER-RQRRSRSREDRNRRRSP 65
            :.||||    |.:..:||.:  ..|||:|.|:|.|.||::..|.::| |.||||||| |:|.|..
  Rat    21 RSRSRSPSDKRSKRGDDRRS--RSRDRDRRRERSRSRDKRRSRSRDRKRLRRSRSRE-RDRSRER 82

  Fly    66 ERQRPRDNVRERSRERGGGAGGGGGGGAEKKAKMDTGDAPPKPLIVDDEEQQDGKEAKVKKEPLS 130
            .|.|.||..|.|||.||..:.....|...|||:..:.         ..|:.:.|..:|.||:
  Rat    83 RRSRSRDRRRSRSRSRGRRSRSSSPGSKSKKAENRSR---------SKEKAEGGDSSKEKKK--- 135

  Fly   131 LEELLDKKKREEEARSKPVFLTKEQRALEAIKRRQEEVERQRAAHDAAREQMAAASKVSISMGTA 195
                 ||..:|:| :.|......:.:..|.:::|:|.||:.|      .||...|.:   ::|..
  Rat   136 -----DKDDKEDE-KEKDAGNFDQNKLEEEMRKRKERVEKWR------EEQRKKAME---NIGEL 185

  Fly   196 MASGAPPPAIVAPPPKPDRRERGGGRDRGDRIDRGERGDDKRAEDLTHKDKEKELEAIRERYLGI 260
                           |.:..|...|:......|..:..|...||...::.:::||:.: :.|:..
  Rat   186 ---------------KKEIEEMKQGKKWSLEDDDDDEDDPAEAEKEGNEMEDEELDPL-DAYMEE 234

  Fly   261 IKKKRRVRRLNDRKFVFDWDAGEDTSIDYNNLYKERHHVQFFGRGN-----------VAGIDIKE 314
            :|::  |::.|.|..     .|                    |.||           |..:..|:
  Rat   235 VKEE--VKKFNMRSV-----KG--------------------GAGNEKKSGPTVTKVVTVVTTKK 272

  Fly   315 QKRTQSKFYGDLLEKRR--TEAEKEQEKVRL-----------KKMKRKEDKQKWDDRHWSEK--- 363
            ......|..|:|:|..:  .|...|:|:|.|           :|:....|..|.:...:.:.
  Rat   273 AVVDADKKKGELMENDQDAMEYSSEEEEVDLQTALTGYQTKQRKLLEPVDHGKIEYEPFRKNFYV 337

  Fly   364 ---ENDEMTERDWRIFR-EDYNVTIKGGRIPNPIRSWNESGFPKEIIDIIDKVGYKEPTPIQRQA 424
               |..:|::.:..:|| |...:|:||...|.||:||.:.|...:|::.:.|.||::|||||.||
  Rat   338 EVPELAKMSQEEVNVFRLEMEGITVKGKGCPKPIKSWVQCGISMKILNSLKKHGYEKPTPIQTQA 402

  Fly   425 IPIGLQNRDIIGVAETGSGKTLAFLIPLLSWIQSLPKIERLEDVDQGPYAIIMAPTRELAQQIEE 489
            ||..:..||:||:|:||||||:|||:|:...|.....:|.    .:||.|:||.||||||.||.:
  Rat   403 IPAIMSGRDLIGIAKTGSGKTIAFLLPMFRHIMDQRSLEE----GEGPIAVIMTPTRELALQITK 463

  Fly   490 ETTKFGQPLGIRTVVVVGGLSREEQGFRLRLGCEIVIATPGRLIDVL---ENRYLVLNQCTYIVL 551
            |..||.:.||:|.|.|.||....||...|:.|.||::.||||:||:|   ..|...|.:.||:||
  Rat   464 ECKKFSKTLGLRVVCVYGGTGISEQIAELKRGAEIIVCTPGRMIDMLAANSGRVTNLRRVTYVVL 528

  Fly   552 DEADRMIDMGFEPDVQKILEYMPVTNLKPDTEEAEDETKLMENFYTKKKYRQTVMFTATMPPAVE 616
            ||||||.||||||.|.:|     |.|::||                    ||||||:||.|.|:|
  Rat   529 DEADRMFDMGFEPQVMRI-----VDNVRPD--------------------RQTVMFSATFPRAME 568

  Fly   617 RLARTYLRRPATVYIGSVGKPTERTEQIVYMMGENDKRKKLMEILSR-KIDPPVIIFVNQKKGAD 680
            .|||..|.:|..|.:|.........||.|.::.|..|..||:|:|.. :....|||||::::.||
  Rat   569 ALARRILSKPIEVQVGGRSVVCSDVEQQVIVIEEEKKFLKLLELLGHYQESGSVIIFVDKQEHAD 633

  Fly   681 VLAKGLEKLGYNSCTLHGGKGQEQREYALAALKSGAKDILVATDVAGRGIDIKDVSLVINYDMAK 745
            .|.|.|.:..|...:||||..|..|:..:...|:|...:||||.||.||:|:|.:.||:||....
  Rat   634 GLLKDLMRASYPCMSLHGGIDQYDRDSIINDFKNGTCKLLVATSVAARGLDVKHLILVVNYSCPN 698

  Fly   746 TIEDYTHRIGRTGRAGKTGCAISFVTKDDSALFYDLKQCVSASPVSTCPPEL----MNHPEAQHK 806
            ..|||.||.|||||||..|.|.:|:|:|.:....|:.:.:..|..:. ||:|    .:..:.|..
  Rat   699 HYEDYVHRAGRTGRAGNKGYAYTFITEDQARYAGDIIKALELSGTAV-PPDLEKLWSDFKDQQKA 762

  Fly   807 PGTVVTK 813
            .|.::.|
  Rat   763 EGKIIKK 769

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10333	NP_609888.2	DUF5401	<66..354	CDD:375164	65/311 (21%)
		SrmB	395..783	CDD:440279	171/391 (44%)
Ddx46	NP_620798.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..227		72/250 (29%)
		DEADc_DDX46	361..582	CDD:350711	115/249 (46%)
		Q motif	372..400		11/27 (41%)
		SrmB	378..793	CDD:440279	176/422 (42%)
		DEAD box	529..532		2/2 (100%)
		KH-I_DDX46	929..1031	CDD:411901