Protein Alignment CG10333 and laf-1

DIOPT Version :10

• Sequence 1: NP_609888.2
• Gene: CG10333 / 35112
• FlyBaseID: FBgn0032690
• Length: 822
• Species: Drosophila melanogaster
• Sequence 2: NP_001254859.1
• Gene: laf-1 / 190611
• WormBaseID: WBGene00002244
• Length: 708
• Species: Caenorhabditis elegans
• Alignment Length: 590
• Identity: 191/590 - (32%)
• Similarity: 280/590 - (47%)
• Gaps: 98/590 - (16%)

  Fly   218 GGGRDRG------DRIDRGERGDDKRAEDLTHKDKEKELEAIRERYLGIIKKKRRVRRLNDRKFV 276
            |||.|||      ||.:||..|...|  |..::|:.
 Worm    66 GGGYDRGYNDNRDDRDNRGGSGGYGR--DRNYEDRG----------------------------- 99

  Fly   277 FDWDAGEDTSIDYNNL-------YKERHH----VQFFGRGNVAGIDIKEQKRTQSKFYGDLLEKR 330
            ::...|...:..|||.       |..:..    ...|.||.....|.....|...:.|.:  ::|
 Worm   100 YNGGGGGGGNRGYNNNRGGGGGGYNRQDRGDGGSSNFSRGGYNNRDEGSDNRGSGRSYNN--DRR 162

  Fly   331 RTEAEKEQEKVRLKKMKRKEDKQKWDDRHWSEKENDEMTERDWRIFR-----------EDYNVTI 384
            ....:.:..:.............||::|    ...||..|::  :|.           |:..|..
 Worm   163 DNGGDGQNTRWNNLDAPPSRGTSKWENR----GARDERIEQE--LFSGQLSGINFDKYEEIPVEA 221

  Fly   385 KGGRIPNPIRSWNESGFPKEIIDIIDKVGYKEPTPIQRQAIPIGLQNRDIIGVAETGSGKTLAFL 449
            .|..:|.||..:::....:.|.:.|...||..|||:|:.:||.....||::..|:||||||.|||
 Worm   222 TGDDVPQPISLFSDLSLHEWIEENIKTAGYDRPTPVQKYSIPALQGGRDLMSCAQTGSGKTAAFL 286

  Fly   450 IPLLSWI-QSLPKIERLEDVDQG------PYAIIMAPTRELAQQIEEETTKFGQPLGIRTVVVVG 507
            :||::.| |..|..........|      |.|::::|||||:.||..|:.||.....|.:.::.|
 Worm   287 VPLVNAILQDGPDAVHRSVTSSGGRKKQYPSALVLSPTRELSLQIFNESRKFAYRTPITSALLYG 351

  Fly   508 GLSR-EEQGFRLRLGCEIVIATPGRLIDVLENRYLVLNQCTYIVLDEADRMIDMGFEPDVQKILE 571
            |... ::|..:|||||.|:||||||||||::...:.:..|.|:||||||||:||||||.:::|:|
 Worm   352 GRENYKDQIHKLRLGCHILIATPGRLIDVMDQGLIGMEGCRYLVLDEADRMLDMGFEPQIRQIVE 416

  Fly   572 YMPVTNLKPDTEEAEDETKLMENFYTKKKYRQTVMFTATMPPAVERLARTYLRRP-ATVYIGSVG 635
                .|..|..||                 |.|.||:||.|..::.||:.:|:.. ..:.:|.||
 Worm   417 ----CNRMPSKEE-----------------RITAMFSATFPKEIQLLAQDFLKENYVFLAVGRVG 460

  Fly   636 KPTERTEQIVYMMGENDKRKKLMEILSRKIDPPV-IIFVNQKKGADVLAKGLEKLGYNSCTLHGG 699
            ..:|...|.:..:.|::||..||::|....|..: ::||..|:||..||..|.:..|...|:||.
 Worm   461 STSENIMQKIVWVEEDEKRSYLMDLLDATGDSSLTLVFVETKRGASDLAYYLNRQNYEVVTIHGD 525

  Fly   700 KGQEQREYALAALKSGAKDILVATDVAGRGIDIKDVSLVINYDMAKTIEDYTHRIGRTGRAGKTG 764
            ..|.:||..|...::|...|||||.||.||:||.:|..|||||:...:::|.||||||||.|..|
 Worm   526 LKQFEREKHLDLFRTGTAPILVATAVAARGLDIPNVKHVINYDLPSDVDEYVHRIGRTGRVGNVG 590

  Fly   765 CAISF 769
            .|.||
 Worm   591 LATSF 595

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10333	NP_609888.2	DUF5401	<66..354	CDD:375164	26/152 (17%)
		SrmB	395..783	CDD:440279	152/385 (39%)
laf-1	NP_001254859.1	SrmB	233..619	CDD:440279	152/384 (40%)