Protein Alignment CG10333 and sacy-1

DIOPT Version :10

• Sequence 1: NP_609888.2
• Gene: CG10333 / 35112
• FlyBaseID: FBgn0032690
• Length: 822
• Species: Drosophila melanogaster
• Sequence 2: NP_491962.1
• Gene: sacy-1 / 172413
• WormBaseID: WBGene00019245
• Length: 630
• Species: Caenorhabditis elegans
• Alignment Length: 619
• Identity: 186/619 - (30%)
• Similarity: 307/619 - (49%)
• Gaps: 141/619 - (22%)

  Fly   249 ELEAIRERYLGIIKKKRRVR--RLNDRKFVFDWDAGEDTSIDYNNLYKERHHVQFFGRGNVAGID 311
            ::||.|.:|   ..::|:::  .:.:|:...:..:|:|.. |.::::             :..:.
 Worm     4 DVEAARRKY---EDRRRKIQEEEMKERRDGMNLSSGDDDQ-DVDDMF-------------LTALQ 51

  Fly   312 IKEQKRTQSKFYGDLLEKRRTEAEKEQEKVRLKKMKRKEDKQKWD-------------------- 356
            .|.:|..:..    ||::.......::|::..|:.|::||||..:
 Worm    52 RKREKVHRRA----LLKQVLAPTMNQKEEIERKRKKKEEDKQSEEARKTLLEKHAEIMETQGVID 112

  Fly   357 --DRHWSEKEN--DEMT-----------------------------------ERDWRIFREDYNV 382
              :|...|:|.  |::|                                   :.|:.|.|:...:
 Worm   113 ESERQLMEEEELLDKVTRGGGLLAVAELTKGEKYEEPIVTAWRPPGHIRRQSQEDYEIQRKRLGI 177

  Fly   383 TIKGGRIPNPIRSWNESGFPKEIIDIIDK-VGYKEPTPIQRQAIPIGLQNRDIIGVAETGSGKTL 446
            :.:|..||.||.|:.|..|||.:::.:.| .|...||.||.|.||:.|..||:||:|.||||||:
 Worm   178 SCEGDHIPPPIGSFLEMKFPKSLLEFMQKQKGIVTPTAIQIQGIPVALSGRDMIGIASTGSGKTM 242

  Fly   447 AFLIPLLSWI----QSLPKIERLEDVDQGPYAIIMAPTRELAQQIEEETTKFGQPLG------IR 501
            .|::||:.:.    ..||.:.     .:||:.:|:.|:||||:||.:...:....||      :|
 Worm   243 TFVLPLVMFCLEQEMKLPFMR-----SEGPFGLIIVPSRELARQIFDLIIEMFDALGKAGLPEMR 302

  Fly   502 TVVVVGGLSREEQGFRLRLGCEIVIATPGRLIDVLENRYLVLNQCTYIVLDEADRMIDMGFEPDV 566
            ..:.:||:...||...:|.|..||:||||||.|:|..:.:.|..|.|:||||||||:|||||.::
 Worm   303 AGLCIGGVPIGEQAKDVRDGIHIVVATPGRLSDMLTKKIINLEVCRYLVLDEADRMLDMGFEDEI 367

  Fly   567 QKILEYMPVTNLKPDTEEAEDETKLMENFYTKKKYRQTVMFTATMPPAVERLARTYLRRPATVYI 631
            :.|                         ||..|..|||::|:||||..::..|::.|.:|..|.:
 Worm   368 KSI-------------------------FYFFKAQRQTLLFSATMPRKIQFFAKSALVKPIVVNV 407

  Fly   632 GSVGKPTERT-EQIVYMMGENDKRKKLMEILS--RKIDPPVIIFVNQKKGAD-----VLAKGLEK 688
            |..|..:... :::.::..||    ||:.:|.  :|..|.|:||..:|...|     :|.||:|
 Worm   408 GRAGAASLNVLQELEFVRSEN----KLVRVLECLQKTSPKVLIFAEKKVDVDNIYEYLLVKGVE- 467

  Fly   689 LGYNSCTLHGGKGQEQREYALAALKSGAKDILVATDVAGRGIDIKDVSLVINYDMAKTIEDYTHR 753
                ..::||||.|..|...:.|.:...||:|||||||.:|:|.:.:..|||:||.:.||:|.||
 Worm   468 ----VASIHGGKDQSDRHAGIEAFRKNEKDVLVATDVASKGLDFQGIEHVINFDMPEDIENYVHR 528

  Fly   754 IGRTGRAGKTGCAISFVT-KDDSALFYDLKQCVS 786
            ||||||:|:.|.|.:|:. |.:.::..||||.::
 Worm   529 IGRTGRSGRKGLATTFINKKSEMSVLSDLKQLLA 562

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10333	NP_609888.2	DUF5401	<66..354	CDD:375164	19/106 (18%)
		SrmB	395..783	CDD:440279	151/407 (37%)
sacy-1	NP_491962.1	SrmB	190..570	CDD:440279	153/412 (37%)