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Protein Alignment CG10333 and DDX3X

DIOPT Version :10

Sequence 1:	NP_609888.2	Gene:	CG10333 / 35112	FlyBaseID:	FBgn0032690	Length:	822	Species:	Drosophila melanogaster
Sequence 2:	NP_001347.3	Gene:	DDX3X / 1654	HGNCID:	2745	Length:	662	Species:	Homo sapiens

Alignment Length:	636	Identity:	207/636 - (32%)
Similarity:	291/636 - (45%)	Gaps:	138/636 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   240 DLTHKDKEK-ELEAIRERYLGIIKKKRRVRRLNDRKFVFDWD-AGEDTSIDYNNLYKERHHVQFF 302
            ||...|.:. ...|.:.||:     ...:|.....|..:|.| :|..:|       |::.....|
Human    20 DLNSSDNQSGGSTASKGRYI-----PPHLRNREATKGFYDKDSSGWSSS-------KDKDAYSSF 72

  Fly   303 GRGNVAGIDIKEQKRTQSKFYGDLLEKRRTEAEKEQEKVRLKKMKRKEDKQKWDDRHWSEKEN-- 365
            |.        :...|.:|.|:.|                     :....:.::|||..|:.:.
Human    73 GS--------RSDSRGKSSFFSD---------------------RGSGSRGRFDDRGRSDYDGIG 108

  Fly   366 --------------------DEMTERDW--------RIFRE---------------DYNVTIKGG 387
                                |:..|.||        |:.:|               |..|...|.
Human   109 SRGDRSGFGKFERGGNSRWCDKSDEDDWSKPLPPSERLEQELFSGGNTGINFEKYDDIPVEATGN 173

  Fly   388 RIPNPIRSWNESGFPKEIIDIIDKVGYKEPTPIQRQAIPIGLQNRDIIGVAETGSGKTLAFLIPL 452
            ..|..|.|:::....:.|:..|:...|..|||:|:.||||..:.||::..|:||||||.|||:|:
Human   174 NCPPHIESFSDVEMGEIIMGNIELTRYTRPTPVQKHAIPIIKEKRDLMACAQTGSGKTAAFLLPI 238

  Fly   453 LSWIQSLPKIERLEDV---------DQGPYAIIMAPTRELAQQIEEETTKFGQPLGIRTVVVVGG 508
            ||.|.|....|.|..:         .|.|.::::|||||||.||.||..||.....:|..||.||
Human   239 LSQIYSDGPGEALRAMKENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYGG 303

  Fly   509 LSREEQGFRLRLGCEIVIATPGRLIDVLENRYLVLNQCTYIVLDEADRMIDMGFEPDVQKILEY- 572
            ....:|...|..||.:::||||||:|::|...:.|:.|.|:||||||||:||||||.:::|:|.
Human   304 ADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQIRRIVEQD 368

  Fly   573 -MPVTNLKPDTEEAEDETKLMENFYTKKKYRQTVMFTATMPPAVERLARTYLRRPATVYIGSVGK 636
             ||                       .|..|.|:||:||.|..::.|||.:|.....:.:|.||.
Human   369 TMP-----------------------PKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGS 410

  Fly   637 PTERTEQIVYMMGENDKRKKLMEILSRK-IDPPVIIFVNQKKGADVLAKGLEKLGYNSCTLHGGK 700
            .:|...|.|..:.|:|||..|:::|:.. .|...::||..|||||.|...|...||...::||.:
Human   411 TSENITQKVVWVEESDKRSFLLDLLNATGKDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDR 475

  Fly   701 GQEQREYALAALKSGAKDILVATDVAGRGIDIKDVSLVINYDMAKTIEDYTHRIGRTGRAGKTGC 765
            .|..||.||...:||...|||||.||.||:||.:|..|||:|:...||:|.||||||||.|..|.
Human   476 SQRDREEALHQFRSGKSPILVATAVAARGLDISNVKHVINFDLPSDIEEYVHRIGRTGRVGNLGL 540

  Fly   766 AISF-------VTKDDSALFYDLKQCVSASPVSTCPPELMNHPEAQHKPGT 809
            |.||       :|||...|..:.||.|        |..|.|.....|..|:
Human   541 ATSFFNERNINITKDLLDLLVEAKQEV--------PSWLENMAYEHHYKGS 583

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 592.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.