Protein Alignment CG10333 and Ddx4

DIOPT Version :10

• Sequence 1: NP_609888.2
• Gene: CG10333 / 35112
• FlyBaseID: FBgn0032690
• Length: 822
• Species: Drosophila melanogaster
• Sequence 2: XP_011242920.1
• Gene: Ddx4 / 13206
• MGIID: 102670
• Length: 738
• Species: Mus musculus
• Alignment Length: 597
• Identity: 194/597 - (32%)
• Similarity: 293/597 - (49%)
• Gaps: 87/597 - (14%)

  Fly   216 ERGGGRDRGDR-----IDRGERGDDKRAE---DLTHKDKEKELEAIRERYLGIIKKKRRVRRLND 272
            :|||.:|..|.     ..||.||..:...   .|...:.|.:.:...:|..|:...::
Mouse   135 KRGGCQDGNDSEASGPFRRGGRGSFRGCRGGFGLGRPNSESDQDQGTQRGGGLFGSRK------- 192

  Fly   273 RKFVFDWDAGEDT---SIDYNNLYKERHHVQFFGRGNVAGIDIKEQKRTQSKFYGDLLEKRRTE- 333
                   .|..|:   .....:.|:.|   ...|||...|::  |:..|.|   |....|..||
Mouse   193 -------PAASDSVQCLTGNGDTYQSR---SGSGRGGYKGLN--EEVVTGS---GKNSWKSETEG 242

  Fly   334 ---AEKEQEKVRLKKMKRKEDKQKWDDRHWSEKENDEMTERDWRIFREDYN---VTIKGGRIPNP 392
               ::.:..||........||            |:.........|..:.|:   |.:.|...|..
Mouse   243 GESSDSQGPKVTYIPPPPPED------------EDSIFAHYQTGINFDKYDTILVEVSGHDAPPA 295

  Fly   393 IRSWNESGFPKEIIDIIDKVGYKEPTPIQRQAIPIGLQNRDIIGVAETGSGKTLAFLIPLLSWIQ 457
            |.::.|:...:.:.:.|.|.||.:.||:|:.:|||.|..||::..|:||||||.|||:|:|:.:.
Mouse   296 ILTFEEANLCQTLNNNIAKAGYTKLTPVQKYSIPIVLAGRDLMACAQTGSGKTAAFLLPILAHMM 360

  Fly   458 ----SLPKIERLEDVDQGPYAIIMAPTRELAQQIEEETTKFGQPLGIRTVVVVGGLSREEQGFRL 518
                :..:.:.|::    |..||:||||||..||..|..||.....:|.||:.||........::
Mouse   361 RDGITASRFKELQE----PECIIVAPTRELINQIYLEARKFSFGTCVRAVVIYGGTQFGHSVRQI 421

  Fly   519 RLGCEIVIATPGRLIDVLENRYLVLNQCTYIVLDEADRMIDMGFEPDVQKILEY--MPVTNLKPD 581
            ..||.|:.||||||:|::....:.|.|..|:||||||||:||||.|:::|::..  ||
Mouse   422 VQGCNILCATPGRLMDIIGKEKIGLKQVKYLVLDEADRMLDMGFGPEMKKLISCPGMP------- 479

  Fly   582 TEEAEDETKLMENFYTKKKYRQTVMFTATMPPAVERLARTYLRRP-ATVYIGSVGKPTERTEQIV 645
                            .|:.|||::|:||.|..::|||..:|:.. ..|.:|.||......:|.:
Mouse   480 ----------------SKEQRQTLLFSATFPEEIQRLAGDFLKSSYLFVAVGQVGGACRDVQQTI 528

  Fly   646 YMMGENDKRKKLMEILSRKIDPPVIIFVNQKKGADVLAKGLEKLGYNSCTLHGGKGQEQREYALA 710
            ..:|:..||:||:|||....|...::||..||.||.:|..|.:...::.::||.:.|.:||.||.
Mouse   529 LQVGQYSKREKLVEILRNIGDERTMVFVETKKKADFIATFLCQEKISTTSIHGDREQREREQALG 593

  Fly   711 ALKSGAKDILVATDVAGRGIDIKDVSLVINYDMAKTIEDYTHRIGRTGRAGKTGCAISFV-TKDD 774
            ..:.|...:||||.||.||:||::|..|||:|:..||::|.||||||||.|.||.||||. |..|
Mouse   594 DFRCGKCPVLVATSVAARGLDIENVQHVINFDLPSTIDEYVHRIGRTGRCGNTGRAISFFDTDSD 658

  Fly   775 SALFYDLKQCVS 786
            :.|...|.:.:|
Mouse   659 NHLAQPLVKVLS 670

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10333	NP_609888.2	DUF5401	<66..354	CDD:375164	32/152 (21%)
		SrmB	395..783	CDD:440279	154/395 (39%)
Ddx4	XP_011242920.1	DEADc_DDX4	266..518	CDD:350810	95/278 (34%)
		SF2_C_DEAD	524..653	CDD:350174	58/128 (45%)