Protein Alignment CG10333 and ddx43

DIOPT Version :10

• Sequence 1: NP_609888.2
• Gene: CG10333 / 35112
• FlyBaseID: FBgn0032690
• Length: 822
• Species: Drosophila melanogaster
• Sequence 2: NP_001315122.1
• Gene: ddx43 / 100136871
• ZFINID: ZDB-GENE-080204-77
• Length: 719
• Species: Danio rerio
• Alignment Length: 729
• Identity: 227/729 - (31%)
• Similarity: 349/729 - (47%)
• Gaps: 170/729 - (23%)

  Fly   193 GTAMASGAPPPAIVAP-----PPKPDRRERGGGRDRGDRIDRGER--GDDKRAEDLTHKDKEKEL 250
            |.|::.....||..||     ||.|     .|.|:| :....|.:  ||.::..:..::|.:.::
Zfish    12 GVAVSKQLTLPAKPAPVKSWRPPSP-----RGARNR-ETSSAGAKFGGDGEQWVNWRNRDSDFDV 70

  Fly   251 EAIRERYLGIIKK-----KRRVRRLNDRKFVFDWDAGEDTSIDYNNLYKERHHV-QFFGRGNVAG 309
                  :.|...|     :.|:.....|.:.   |.|:.:|:..|   .|...| :..|||   |
Zfish    71 ------FDGAAGKNNSYSRSRIGPTRSRGYA---DRGDSSSVTLN---VENSLVGRIIGRG---G 120

  Fly   310 IDIKEQKRTQSKFYGDLLEKRRTEAEKE---------QEKVR----------------------- 342
            ..|:|.:.:.    |..::..|...|.|         |.|.:
Zfish   121 AKIRELQESS----GASIKITRGAHEAEVLICGSCDAQHKAKDMIEDLVHENMGGSGYRNGNSSQ 181

  Fly   343 ------------------------------LKKMKRKEDKQKWDDRHWSEK----ENDEMTERD- 372
                                          |::.:.|.:..||.|....:|    |...:..|.
Zfish   182 GYQNNSCWSASAVKAAAAAAPAPTPIDWTSLRENRDKYEAMKWQDLPVLKKNFYIEAKSVAARSA 246

  Fly   373 -----WRIFREDYNV---TIKGG---RIPNPIRSWNE--SGFPKEIIDIIDKVGYKEPTPIQRQA 424
                 ||  :|:.|:   .:|.|   .||||:.::.|  :.:| .|::.|.:||:|:|||||.||
Zfish   247 EEVKIWR--KENNNIFVDDLKDGDKRTIPNPVCTFEEAFAHYP-GIMENIVRVGFKKPTPIQSQA 308

  Fly   425 IPIGLQNRDIIGVAETGSGKTLAFLIPLLSWI----QSLPKIERLEDVDQGPYAIIMAPTRELAQ 485
            .|:.|...|:||:|:||:|||||:|:|  .:|    |.:|:.:|     .||..:::.||||||.
Zfish   309 WPVVLNGIDLIGIAQTGTGKTLAYLLP--GFIHMDGQPMPRDKR-----NGPGMLVLTPTRELAL 366

  Fly   486 QIEEETTKFGQPLGIRTVVVVGGLSREEQGFRLRLGCEIVIATPGRLIDVLENRYLVLNQCTYIV 550
            |||.|..|:... |.:::.:.||..|..|...:..|.:|||||||||.|:..|..:.|...||:|
Zfish   367 QIEAECNKYSYK-GFKSICIYGGGDRNAQIKVVTSGVDIVIATPGRLNDLQMNELINLRSITYLV 430

  Fly   551 LDEADRMIDMGFEPDVQKILEYMPVTNLKPDTEEAEDETKLMENFYTKKKYRQTVMFTATMPPAV 615
            |||||||:||||||.:.||     :.:::||                    |||||.:||.||.|
Zfish   431 LDEADRMLDMGFEPQIMKI-----ILDIRPD--------------------RQTVMTSATWPPGV 470

  Fly   616 ERLARTYLRRPATVYIGSVGKPTERT-EQIVYMMGENDKRKKLMEILSRKIDP--PVIIFVNQKK 677
            .|||::||:.|..||:|::......| :|.|..:.|::|:..:.:.:.| ::|  .|:|||.:|.
Zfish   471 RRLAKSYLKDPMMVYVGTLDLAAVNTVQQTVLFVQEDEKKDYVFDFIHR-MEPLDKVLIFVGKKL 534

  Fly   678 GADVLAKGLEKLGYNSCTLHGGKGQEQREYALAALKSGAKDILVATDVAGRGIDIKDVSLVINYD 742
            .||.|:..|...|....:|||.:.|..||.||...|.|...||||||:|.||:|:.|::.|.|||
Zfish   535 KADDLSSDLCLQGIAVQSLHGDREQCDREEALQDFKDGRVRILVATDLASRGLDVHDITHVFNYD 599

  Fly   743 MAKTIEDYTHRIGRTGRAGKTGCAISFVTKDDSALFYDLKQCVSASPVSTCPPELMNHPEAQHKP 807
            ..:.:|:|.||:|||||||::|.:::.||::|..:..:|...:..|. ...|.||:...|...
Zfish   600 FPRNVEEYVHRVGRTGRAGRSGESVTLVTREDWRVAAELITILERSG-QDVPEELVLMAERYE-- 661

  Fly   808 GTVVTKKRREEKIF 821
                 |.|||:::|
Zfish   662 -----KHRREKEMF 670

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10333	NP_609888.2	DUF5401	<66..354	CDD:375164	40/235 (17%)
		SrmB	395..783	CDD:440279	161/396 (41%)
ddx43	NP_001315122.1	KH-I_DDX43_DDX53	102..167	CDD:411858	16/74 (22%)
		SrmB	287..669	CDD:440279	169/424 (40%)