Protein Alignment CG10413 and VHC1

DIOPT Version :10

• Sequence 1: NP_609887.1
• Gene: CG10413 / 35111
• FlyBaseID: FBgn0032689
• Length: 941
• Species: Drosophila melanogaster
• Sequence 2: NP_009794.3
• Gene: VHC1 / 852537
• SGDID: S000000439
• Length: 1120
• Species: Saccharomyces cerevisiae
• Alignment Length: 936
• Identity: 294/936 - (31%)
• Similarity: 467/936 - (49%)
• Gaps: 136/936 - (14%)

  Fly    57 DPDRSGR-TLGTFAGVFSPVALSMFSALVFIRVGYIVGNAGLYVTLLQFLIAYGILLFTVASVCA 120
            |||...: .|||:.|||.|.||::.|.|:|:|.|:|:|..|:..|:...|::|.|.|.|..|:.|
Yeast    54 DPDNPNKDKLGTYDGVFVPTALNVLSILMFLRFGFILGQLGIICTIGLLLLSYTINLLTTLSISA 118

  Fly   121 ISTNGAIEGGGVYFMISRTLGLEFGGSIGTLFFFANVVGSAMAISGCTEGIMDNFGPRGHFVSGD 185
            |||||.:.|||.|:||||:||.|||||||.:||...|..:.|...|..|.::.|.   |:...|:
Yeast   119 ISTNGTVRGGGAYYMISRSLGPEFGGSIGLVFFLGQVFNAGMNAVGIIEPLLYNL---GYSAQGE 180

  Fly   186 ------SHLPDGDWWRFLTSSMINTLQLLVCLVGAALFAKTSVIILATVTVCLFATYFSFLFVGA 244
                  ..||.|.|..|..:::|..|...|..||:...::...|:              ||.:.|
Yeast   181 PPAALGELLPRGHWHEFTYATVILFLCFSVAFVGSQTVSRAGNIL--------------FLVLAA 231

  Fly   245 TNNTIPVPGDNILSNTTTFLDYTGLNATTLRDNLGSHYGRDYTSN---GKQVDFSTTFGVLFSGV 306
            :..:||:........|...:.|||.:..|..|||..|..:....:   ||:. |:..|||.|...
Yeast   232 SIFSIPLSALIRSPFTEGGISYTGPSWQTFHDNLLPHLTKGAAGSLLKGKET-FNDLFGVFFPAT 295

  Fly   307 TGIMAGANMSGELKNPSKSIPYGTLSAVAFTFVSYIILSFLMSCTTPYFTMQNNYLFLMPVN--L 369
            .||.|||.||.||:.||||||.|||..:.|||:.|.::.|.|.|:.|..::.:....:..::  .
Yeast   296 AGIFAGAGMSSELRKPSKSIPKGTLWGLLFTFICYAVVVFSMGCSIPRRSLYDEVQIIQTISSVQ 360

  Fly   370 WPPFTAIGILTATFSTSLSNLIGSSRILEALSKDQVFGSLLNFVIHGTWKGNPIAAVAVSWCLVE 434
            |..|  :|.:..:..:.:..::|::.:|||::||.:...|..|. |     :|:.::..:|.|.:
Yeast   361 WVIF--MGEMATSLFSIIVGMLGAAYVLEAIAKDNIIPGLEIFA-H-----SPLYSLIFTWILTQ 417

  Fly   435 CILLIGSFNIIAQINSVLFMLSYLATNLACLGIELTGAPNFRPLFKFFTWHTCLVGLLGTLIMMF 499
             :.|....|.||...::.|:::::..||||..:.::.||||||.||:|..:|..:|.|.:::.|.
Yeast   418 -LCLFSDVNKIATFITMTFLMTFVVMNLACFLLGISSAPNFRPSFKYFNRYTTAIGALLSVVAML 481

  Fly   500 VINFIYASSCIILCLILVIALHLFSPATQAAQWGSISQALMFHQVRKYLLMLDPRKDHVKFWRPQ 564
            :::.|.||...:..::|.:.:|.|||   ...||.:||:|::||||||||.|  |:|::|:||||
Yeast   482 IVDGISASVLFLAMILLFLFIHYFSP---PKSWGDVSQSLIYHQVRKYLLRL--RQDNIKYWRPQ 541

  Fly   565 ILLLVSSPRSCCPLVDFVNDLKKSGLYIIGHVKL-GDF-KGIEDAEDNQQ-WWSFLDHMRVKAFT 626
            |||.|.:||:...|:.|.|.|||.||||:|||.: .|| |.:.:.:..|: |....|...:|||.
Yeast   542 ILLFVDNPRTSWNLIRFCNHLKKGGLYILGHVAVTADFPKQLNELKTQQKAWMKIRDMAAIKAFV 606

  Fly   627 EVTLSRSIREGVQHLIRLSGIGAMKPNTIILGFYDSEAPRDFFQNGSSPYKTDDFNNGEIQ---- 687
            :|....|:..|::::...||:|.||||..::||:|.|:.|.......|.      ||.:.|
Yeast   607 QVGTGPSLIWGIRNVFIGSGLGGMKPNITVVGFFDLESYRKHIPQSRSQ------NNLQKQVEIK 665

  Fly   688 -------------NFPIRRD--GDPKQFQIQEYVQILCDTLRMKKNLCLCRNFQRLD---KNFIS 734
                         |.|:..|  .:..:..:|::|||:.|...|:.|:.:...|:.|:   |....
Yeast   666 ATVPRSTCSDVKINVPLPTDECKNETKVNVQQWVQIVEDLSLMQSNIAIAHGFKNLEIPNKRDSC 730

  Fly   735 MSKHVKYIDVWPINIFN--PTSGDP-------FDMVSLFMMQLAVIMLA--KWKH---LRVRIFL 785
            ..|  |.||::||.:..  ...||.       ||..:| ::|||.|::.  :||.   |||.:|:
Yeast   731 FPK--KTIDLYPIQMCGKVEAKGDQPAAITTNFDTYTL-ILQLAAILVTVPEWKRTHSLRVILFV 792

  Fly   786 CEANDERTVGTFDTQTPQMEIFSKMKLEQSLKELRITADIVEIQEWSRDTDFSRHARTLKQFTAQ 850
             |....||..|             .::::.|:.|||.|:::.:              :|.||  :
Yeast   793 -EQEYHRTNET-------------QRMKKLLQVLRIDAEVLVV--------------SLDQF--R 827

  Fly   851 ADNVVLEDDDEVGEETLNRSLLYMQRANQIIRERSDQTALSFIYLAAPPKLSAPDFAQRSASYME 915
            ..|.:::.|..| .:.:|..|...:....::..| |.......:....|:..|..|.| |..|..
Yeast   828 VYNTIVKGDPIV-FDYVNSKLADNEWWKDLVEAR-DTLKPKRRFSTIEPQTIAKQFTQ-SRKYTS 889

  Fly   916 LLTELTADLPPTILVHGVSTVTSTTL 941
            .:.:|           |||...:|.:
Yeast   890 GVQKL-----------GVSFTMNTRM 904

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10413	NP_609887.1	AA_permease_2	22..932	CDD:459263	290/925 (31%)
VHC1	NP_009794.3	AA_permease_2	45..824	CDD:459263	273/838 (33%)