Protein Alignment CG10413 and Slc12a2

DIOPT Version :9

• Sequence 1: NP_001286048.1
• Gene: CG10413 / 35111
• FlyBaseID: FBgn0032689
• Length: 941
• Species: Drosophila melanogaster
• Sequence 2: NP_113986.2
• Gene: Slc12a2 / 83629
• RGDID: 620809
• Length: 1203
• Species: Rattus norvegicus
• Alignment Length: 1047
• Identity: 258/1047 - (24%)
• Similarity: 440/1047 - (42%)
• Gaps: 282/1047 - (26%)

  Fly    46 DGDGYVEFGMQDPDRSGRTLGTFAGVFSPVALSMFSALVFIRVGYIVGNAGLYVTLLQFLIAYGI 110
            :..|.|:||.            ..||.....|:::..::|||:.:|||.||:.:::|...:|..:
  Rat   269 ESKGVVKFGW------------IKGVLVRCMLNIWGVMLFIRLSWIVGQAGIGLSVLVIAMATVV 321

  Fly   111 LLFTVASVCAISTNGAIEGGGVYFMISRTLGLEFGGSIGTLFFFANVVGSAMAISGCTEGIMDNF 175
            ...|..|..||:|||.:.|||.|::|||:||.||||:||.:|.|||.|..||.:.|..|.:::..
  Rat   322 TTITGLSTSAIATNGFVRGGGAYYLISRSLGPEFGGAIGLIFAFANAVAVAMYVVGFAETVVELL 386

  Fly   176 GPRGHFVSGDSHLPDGDWWRFLTSSMINTLQLL-----VCLVGAALF-----AKTSVIILATVTV 230
              :.|.:              |....||.::::     |.|:|.::.     ||..:::|..:.:
  Rat   387 --KEHSI--------------LMIDEINDIRIIGAITVVVLLGISVAGMEWEAKAQIVLLVILLL 435

  Fly   231 CLFATYFSFLFVGATNNTIPVPGDNILSNTTTFLD--------YTGLNATTLRDNLGSHYGRDYT 287
            .:                    .|.::.   ||:.        :.|..:....:|.|..:..:.|
  Rat   436 AI--------------------ADFVIG---TFISLDSKKPKGFFGYKSEIFSENFGPDFREEET 477

  Fly   288 SNGKQVDFSTTFGVLFSGVTGIMAGANMSGELKNPSKSIPYGTLSAVAFTFVSYI---------- 342
                   |.:.|.:.|...|||:||||:||:|.:|..:||.|||.|:..|.|.||
  Rat   478 -------FFSVFAIFFPAATGILAGANISGDLADPQSAIPKGTLLAILITTVVYIGIAVSVGSCV 535

  Fly   343 -----------ILSFLMSCT----------------TPYFTMQNNYLFLMPVNLWPPFTAIGILT 380
                       |.:.|.:||                |..:.:.||:..:..|:.:.|..:.||.:
  Rat   536 VRDATGNVNDTITTELTNCTSAACKLNFDFSYCESNTCSYGLMNNFQVMSMVSGFAPLISAGIFS 600

  Fly   381 ATFSTSLSNLIGSSRILEALSKDQVFGSLLNFVIHGTWKGN-PIAAVAVSWCLVECILLIGSFNI 444
            ||.|::|::|:.:.:|.:||.||.::.:...|. .|..|.| |:....:::.:....:||...|:
  Rat   601 ATLSSALASLVSAPKIFQALCKDNIYPAFQMFA-KGYGKNNEPLRGYILTFLIALGFILIAELNV 664

  Fly   445 IAQINSVLFMLSYLATNLACLGIELTGAPNFRPLFKFFTWHTCLVGLLGTLIMMFVINFIYASSC 509
            ||.|.|..|:.||...|.:.....|..:|.:||.||::.....|.|.:...|:|||||:..|
  Rat   665 IAPIISNFFLASYALINFSVFHASLAKSPGWRPAFKYYNMWISLTGAILCCIVMFVINWWAA--- 726

  Fly   510 IILCLILVIALHLFSPATQA-AQWGSISQALMFHQVRKYLLMLDPRKDHVKFWRPQILLLVSSPR 573
             :|..::|:.|:::....:. ..|||.:|||.:....::.:.|...:||||.:|||.|::..||.
  Rat   727 -LLTYVIVLGLYIYVTYKKPDVNWGSSTQALTYLSALQHSIRLSGVEDHVKNFRPQCLVMTGSPN 790

  Fly   574 SCCPLVDFVNDLKKS-GLYIIGHVKLGDFKGI--EDAEDNQQWWSFLDHMRVKAFTEVTLSRSIR 635
            |...|:..|:|..|: ||.|.|||.:|..:..  |.:.|..::..:|...::|||.....:..:|
  Rat   791 SRPALLHLVHDFTKNVGLMICGHVHMGPRRQAMKEMSIDQAKYQRWLIKNKMKAFYAPVHADDLR 855

  Fly   636 EGVQHLIRLSGIGAMKPNTIILGF----------------------------------------- 659
            ||.|:|::.:|:|.|||||::|||
  Rat   856 EGAQYLMQAAGLGRMKPNTLVLGFKKDWLQADMRDVDMYINLFHDAFDIQYGVVVIRLKEGLDIS 920

  Fly   660 --------------------------YDSEAPRDFFQ-NGSSPY-KTDDFNNGEIQNFPIRR--- 693
                                      |..::.:|.|: :|..|. :.|:..:|:....|:.:
  Rat   921 HLQGQEELLSSQEKSPGTKDVVVNVDYSKKSDQDAFKASGEKPITQKDEEEDGKTSTQPLLKKES 985

  Fly   694 DGDPKQFQIQEYVQILCDTLRMKKNLCLCRNFQRLDKNFISMSKHVKYIDVWPINIFNPTSGDPF 758
            .|......:.:...:...|...||.          .||         .||||.:          |
  Rat   986 KGPVAPLNVADQKLLEASTQFQKKQ----------GKN---------TIDVWWL----------F 1021

  Fly   759 DMVSL-FMMQLAVIMLAKWKHLRVRIFLCEA-----NDERTVGTFDTQTPQMEIFSKMKLEQSLK 817
            |...| .::...:....|||..::|:|:...     :|.|.:.|         :.||.:::.|
  Rat  1022 DDGGLTLLIPYLLTTKKKWKDCKIRVFIGGKINRIDHDRRAMAT---------LLSKFRIDFS-- 1075

  Fly   818 ELRITADIVEIQEWSRDTDFSRHARTLKQFTAQADNVV----LEDDDEV---------------- 862
            ::.:..||              :.:..|:.....|:::    |.:||:.
  Rat  1076 DIMVLGDI--------------NTKPKKENIVAFDDMIEPYRLHEDDKEQDIADKMKEDEPWRIT 1126

  Fly   863 -GEETLNRSLLYMQ-RANQIIRERSDQTALSFIYLAAPPKLSAPDFAQRSASYMELLTELTADLP 925
             .|..|.::..|.| |.|::::|.|  :..:.|.::.|   .|...|..||.||..|..|:.|||
  Rat  1127 DNELELYKTKTYRQIRLNELLKEHS--STANIIVMSLP---VARKGAVSSALYMAWLEALSKDLP 1186

  Fly   926 PTILVHG 932
            |.:||.|
  Rat  1187 PILLVRG 1193

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10413	NP_001286048.1	2a30	22..932	CDD:273347	257/1045 (25%)
		SLC12	577..932	CDD:281515	95/457 (21%)
Slc12a2	NP_113986.2	2a30	207..1203	CDD:273347	258/1047 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166352212
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.840