Protein Alignment CG10413 and slc12a5b

DIOPT Version :9

• Sequence 1: NP_001286048.1
• Gene: CG10413 / 35111
• FlyBaseID: FBgn0032689
• Length: 941
• Species: Drosophila melanogaster
• Sequence 2: XP_009302423.1
• Gene: slc12a5b / 797331
• ZFINID: ZDB-GENE-080707-1
• Length: 1126
• Species: Danio rerio
• Alignment Length: 1152
• Identity: 271/1152 - (23%)
• Similarity: 462/1152 - (40%)
• Gaps: 298/1152 - (25%)

  Fly     6 EQETAPIANSRSGRTGSVFRSFGSLFGGSQNSGDRPHTPQDGDGYVEFGMQDPDRSGRTLGTFAG 70
            |.:|:|:.:|..    |...::.:|..||:...:    .::.:...:...|.|     .:||..|
Zfish    54 EMDTSPMVSSLL----SSLANYSNLTQGSKEHEE----AENNEEARKKAAQAP-----RMGTIMG 105

  Fly    71 VFSPVALSMFSALVFIRVGYIVGNAGLYVTLLQFLIAYGILLFTVASVCAISTNGAIEGGGVYFM 135
            |:.|...::...::|:|:.::||..|:..|.....:.....:.|..|:.||:|||.:..||.|:|
Zfish   106 VYLPCLQNILGVILFLRMTWLVGVGGVLGTFTIVFMCCSTTMLTAISMSAIATNGVVPAGGSYYM 170

  Fly   136 ISRTLGLEFGGSIGTLFFFANVVGSAMAISGCTEGIMDNFGPRGHFVSGDSHLPDGDWWRFLTSS 200
            |||:||.||||::|..||.......||.|.||.|.::....|.......:. |...:....|.::
Zfish   171 ISRSLGPEFGGAVGICFFLGTTFAGAMYILGCIEILLIYIVPSAAIFKMEG-LEGSEAEAALLNN 234

  Fly   201 M------INTLQLLVCLVGAALFAKTSVIILATVTVCLFATY------------FSFLFVGATNN 247
            |      :.|...:|..||.....|.:::.||.|.:.:.|.|            |....:|  |.
Zfish   235 MRVYGTIVLTFMAIVVFVGVKYVNKLALVFLACVILSILAIYAGVIKTSFDPPDFPVCVLG--NR 297

  Fly   248 TIPVPGDNILSNT--------TT-----FLDYTGLNAT----------------------TLRDN 277
            |:.....:|.:.|        ||     |.|...||||                      .|.:|
Zfish   298 TLVSKAYDICAKTIERGNATITTKLWRSFCDSEFLNATCDEYFVNNNISQIQGIPGVTSGILAEN 362

  Fly   278 LGSHYGR------------------DYTSNGKQV--DFSTTF----GVLFSGVTGIMAGANMSGE 318
            |.|.|..                  ..|::.:.|  |.::.|    |:.|..|||||||:|.||:
Zfish   363 LFSGYMEKNSVLEKRGLQAVQDPELPVTNSNRYVLADITSFFTLLVGIYFPSVTGIMAGSNRSGD 427

  Fly   319 LKNPSKSIPYGTLSAVAFTFVSYIILSFLMSCTTPYFTMQNNYLFLMPVNL------WP-PFTAI 376
            |::..||||.||:.|:..|.:.|:....|.........:::.:...:..||      || |:..:
Zfish   428 LQDAQKSIPVGTILAITTTSIIYMSSVILFGACVDGVVLRDKFGEGVSGNLVIGTLAWPSPWVIV 492

  Fly   377 -GILTATFSTSLSNLIGSSRILEALSKD------QVFGSLLNFVIHGTWKGNPIAAVAVSWCLVE 434
             |...:|....|.:|.|:.|:|:|:::|      :|||       ||...|.|..|:.::.|:.|
Zfish   493 FGSFFSTCGAGLQSLTGAPRLLQAIARDGIIPFLRVFG-------HGKANGEPTWALLLTACICE 550

  Fly   435 CILLIGSFNIIAQINSVLFMLSYLATNLACLGIELTGAPNFRPLFKFFTWHTCLVGLLGTLIMMF 499
            ..:||.|.:.:|.|.|:.|::.|:..||||....|...||:||.|||:.|...|:|:...|.:||
Zfish   551 SGILIASLDAVAPILSMFFLMCYMFVNLACALQTLLRTPNWRPRFKFYHWALSLLGMSLCLTLMF 615

  Fly   500 VINFIYASSCIIL--CLILVIALHLFSPATQAAQWGSISQALMFHQVRKYLLMLDPRKDHVKFWR 562
            :.::.||...:::  |:...|.   |..|.:  :||...:.:.....|..|:.|:....|.|.||
Zfish   616 LCSWYYAIVAMVIAGCIYKYIE---FCGAEK--EWGDGIRGISLSAARFALMRLEEGPPHTKNWR 675

  Fly   563 PQILLL--------VSSPRSCCPLVDFVNDLKK-SGLYIIGHVKLGDFKGIE--DAEDNQQWWSF 616
            ||||:|        |..||    |:...:.||. .||.|:|....|.:...:  ..:.:|.....
Zfish   676 PQILVLTTLDGEQNVEQPR----LLSLTSQLKAGKGLTIVGACIEGTYLNNQPKTQKADQSLRKL 736

  Fly   617 LDHMRVKAFTEVTLSRSIREGVQHLIRLSGIGAMKPNTIILGFYDSEAPRDFFQNGSSPYKTDDF 681
            ::..:||.|::|.:|.::|:...|||:..|:|.::.||:::.|     |:::.|
Zfish   737 MEVEKVKGFSQVVISSNLRDATSHLIQAGGLGGLRHNTVLVSF-----PKNWKQ----------- 785

  Fly   682 NNGEIQNFPIRRDGDPKQFQIQEYVQILCDTLRMKKNLCLCRNFQRLDKNFISMSKHVKYIDVWP 746
                          ..:..:.:.:::::.:|......|.:.:|......|....::  .:||||.
Zfish   786 --------------AEEHHRCRNFIEVVRETTAGHMALLVPKNISAYPSNGERFTE--GHIDVWW 834

  Fly   747 INIFNPTSGDPFDMVSLFMMQLAVIMLAKWKHLRVRIFLCEANDERTVG------TF------DT 799
            |    ...|....::...:.|..|     |:..::|||.....|:.::.      ||      |.
Zfish   835 I----VHDGGMLMLLPFLLRQHKV-----WRKCKMRIFTVAQMDDNSIQMKKDLMTFLYHLRLDA 890

  Fly   800 QTPQMEIFSK----------MKLEQS---LKELRITADIVEIQEWSRDTDFSR------------ 839
            ....:|:...          :.:||.   |||:.:|.:..| :|....||.||
Zfish   891 AVEVVEMLDNDISAYTYEKTLMMEQRSQILKEMHLTKNERE-REIQSITDVSRGSIRRKNPSNLH 954

  Fly   840 --------------------------HAR------------------------------------ 842
                                      |.|
Zfish   955 PQRSIAEESVAGSGEEKPEEESVRVSHPRQVQLIQGKNATPTPTSPTSPTAPTPATMSPGEEIQM 1019

  Fly   843 TLKQFTAQADNVVLEDDDEVGE--------ETLNRS----LLYMQRANQIIRERSDQTALSFIYL 895
            |....|.:|:|..:.:.:.:.:        |.||:|    :.:.|:.|::|.::|.:..|..:.:
Zfish  1020 TWTDDTEKANNPAVANPENIKDMFNMKPEWENLNQSNVRRMHHAQKLNEVIVKKSQEAKLVLLNM 1084

  Fly   896 AAPPKLSAPDFAQRSASYMELLTELTADLPPTILVHG----VSTVTS 938
            ..||:....:     .:|||.|..||..|...:||.|    |.|:.|
Zfish  1085 PGPPRNRTGE-----ENYMEFLEVLTEGLNRVLLVRGGGREVITIYS 1126

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10413	NP_001286048.1	2a30	22..932	CDD:273347	263/1124 (23%)
		SLC12	577..932	CDD:281515	84/468 (18%)
slc12a5b	XP_009302423.1	2a30	24..1126	CDD:273347	270/1150 (23%)
		SLC5-6-like_sbd	148..>288	CDD:294310	43/140 (31%)
		SLC12	693..1126	CDD:281515	89/483 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170594122
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.840