Protein Alignment CG10413 and slc12a9

DIOPT Version :10

• Sequence 1: NP_609887.1
• Gene: CG10413 / 35111
• FlyBaseID: FBgn0032689
• Length: 941
• Species: Drosophila melanogaster
• Sequence 2: NP_001122020.1
• Gene: slc12a9 / 793341
• ZFINID: ZDB-GENE-050208-222
• Length: 899
• Species: Danio rerio
• Alignment Length: 940
• Identity: 404/940 - (42%)
• Similarity: 553/940 - (58%)
• Gaps: 95/940 - (10%)

  Fly    32 GGSQNSGDRPHTPQDGDGYVEFGMQDPDRSGRTLGTFAGVFSPVALSMFSALVFIRVGYIVGNAG 96
            |||..:|:               ..:|....|.|.||.||..|..|||||.::|:|.|::||:||
Zfish    25 GGSAGTGE---------------ASNPKTDPRKLNTFFGVMVPTILSMFSIVLFLRTGFVVGHAG 74

  Fly    97 LYVTLLQFLIAYGILLFTVASVCAISTNGAIEGGGVYFMISRTLGLEFGGSIGTLFFFANVVGSA 161
            |...||...:||.|:..|:.|:||||||||:||||.||||||:||.|||||||.:|:.|.|....
Zfish    75 LLHGLLMLFVAYFIISLTILSICAISTNGAVEGGGAYFMISRSLGPEFGGSIGLMFYLAKVCACG 139

  Fly   162 MAISGCTEGIMDNFG--PRGHFVSGDSHLPDGDWWRFLTSSMINTLQLLVCLVGAALFAKTSVII 224
            :.:.|..|.|||.||  |......|...||.|.|:..|.||::..|.:|||||||.::||.|.:|
Zfish   140 VYVLGLVEAIMDVFGQDPGSSVAQGLRVLPQGYWYTVLYSSVVLLLCMLVCLVGAHIYAKASFLI 204

  Fly   225 LATVTVCLFATYFSFLFVGATN-NTIPVPGDNILSNTTTFLDYTGLNATTLRDNLGSHYGRDYTS 288
            |..|||.|.:...|.|.|.... |.....|:|  .:.|....|||.|:|||::|||..|..||::
Zfish   205 LLVVTVSLISIIISPLIVSPQGFNITHTYGNN--HSVTVSPSYTGFNSTTLKNNLGPRYSLDYST 267

  Fly   289 NGKQVDFSTTFGVLFSGVTGIMAGANMSGELKNPSKSIPYGTLSAVAFTFVSYIILSFLMSCTTP 353
            | ..:.|:|.|.|:|:..|||||||||||||||||:|||.||:.|||:||..|::|..|:|.|..
Zfish   268 N-TMMSFATVFAVMFTSCTGIMAGANMSGELKNPSESIPKGTIMAVAYTFTVYVLLYLLLSSTCD 331

  Fly   354 YFTMQNNYLFLMPVNLWPPFTAIGILTATFSTSLSNLIGSSRILEALSKDQVFGSLLNFVIHGTW 418
            ...:.|:|.....||:||||..||:..|:.|.::.::||:||||.||:.||:||..|......:.
Zfish   332 RSLLLNDYAVFQRVNVWPPFVTIGVYCASLSAAMCSMIGASRILHALALDQLFGLPLAPAAVTSS 396

  Fly   419 KGNPIAAVAVSWCLVECILLIGSFNIIAQINSVLFMLSYLATNLACLGIELTGAPNFRPLFKFFT 483
            .|||..:|..:|.||:|.|..|..|:||.|.:|.::|:|.|.:||||.:|...||||||.|:||:
Zfish   397 SGNPWVSVLYTWALVQCTLFAGQLNVIAGIVTVFYLLAYAAVDLACLALEWASAPNFRPTFQFFS 461

  Fly   484 WHTCLVGLLGTLIMMFVINFIYASSCIILCLILVIALHLFSPATQAAQWGSISQALMFHQVRKYL 548
            |||||:|::..::||||||.:|:|:.|:|.|:|::.||..||   .:.||.|||||:||||||||
Zfish   462 WHTCLLGIISCVVMMFVINPVYSSASIVLLLLLLLFLHYRSP---TSSWGYISQALIFHQVRKYL 523

  Fly   549 LMLDPRKDHVKFWRPQILLLVSSPRSCCPLVDFVNDLKKSGLYIIGHVKLGDFKGIEDAEDNQQ- 612
            ||||.|||||||||||:||:||:|||.|.|:.|||.|||.||:::|||::||. .:..|:..|.
Zfish   524 LMLDSRKDHVKFWRPQVLLMVSNPRSSCQLICFVNQLKKGGLFVLGHVQIGDL-DVLPADPVQPQ 587

  Fly   613 ---WWSFLDHMRVKAFTEVTLSRSIREGVQHLIRLSGIGAMKPNTIILGFYDSEAPRDFFQNGSS 674
               |.|.:|.:.||||.::|||.|:|:|.|||:|::|:|.|||||::|||||:..|.|:|.....
Zfish   588 YNFWLSLVDKLGVKAFVDLTLSPSVRQGTQHLLRITGLGGMKPNTLVLGFYDNSYPEDYFLQDPV 652

  Fly   675 PYKTDDFNNGEIQNF------------PIRRDGDPKQFQIQEYVQILCDTLRMKKNLCLCRNFQR 727
            ..|.|   ..|..||            |:|....|:..|.||||.|:.|.::|.||:||.|.|.:
Zfish   653 FCKGD---RSEGDNFGVDLPSLQAHFPPVRHAESPRALQPQEYVSIIQDAIKMGKNICLARYFFQ 714

  Fly   728 LDKNFISMSKHVKY---------IDVWPINIFNPTSGDPFDMVSLFMMQLAVI--MLAKWKHLRV 781
            |...    ||...|         |||||.|:..|.|....|:.|||::|:|.:  |.:.|:..|:
Zfish   715 LPPE----SKGATYMWGKDSMDTIDVWPTNLLTPGSASYADVGSLFLLQMACVLNMASGWRRARL 775

  Fly   782 RIFLCEANDERTVGTFDTQTPQMEIFSKMKLEQSLKELRITADIVEIQEWSRDTDFSRHARTLKQ 846
            |||:|..::....|....:....|:..|:::..::|          |..|.......|...|..|
Zfish   776 RIFVCVESESEDQGWLAKEEQFRELLGKLRIRAAIK----------IVAWDNVARMVRGPNTESQ 830

  Fly   847 FTAQADNVVLEDDDEVGEETLNRSLLYMQRANQIIRERSDQTALSFIYLAAPPKLSAPDFAQRSA 911
                   .|.||              ::...|.:::|.|...|:.|:||..||  |:.:.:|:
Zfish   831 -------PVSED--------------FLCAVNGLLKEHSSTAAVRFLYLPDPP--SSCELSQQ-- 870

  Fly   912 SYMELLTELTADLPPTILVHGVSTVTSTTL 941
             |:..|..||.||.||:|:|||:.||.|.|
Zfish   871 -YLTQLDTLTRDLGPTLLIHGVTPVTCTEL 899

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10413	NP_609887.1	AA_permease_2	22..932	CDD:459263	397/929 (43%)
slc12a9	NP_001122020.1	AA_permease_2	12..890	CDD:459263	397/929 (43%)