DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10413 and CG12773

DIOPT Version :9

Sequence 1:	NP_001286048.1	Gene:	CG10413 / 35111	FlyBaseID:	FBgn0032689	Length:	941	Species:	Drosophila melanogaster
Sequence 2:	NP_001284773.1	Gene:	CG12773 / 31082	FlyBaseID:	FBgn0024365	Length:	712	Species:	Drosophila melanogaster

Alignment Length:	514	Identity:	131/514 - (25%)
Similarity:	220/514 - (42%)	Gaps:	97/514 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSASAEQETAPIANSRSGRTGSVFRSFGSLFGGSQNSGD------RPHTPQDGDGYVEFGMQDPD 59
            |:.|:|      .|...||....::.||  .||.:: ||      |..|..:..|:|:.|.:...
  Fly     1 MTNSSE------GNGNGGRRTVDWQRFG--LGGDED-GDVAVTSFRQRTNNNTGGFVDLGNEYTY 56

  Fly    60 RSGR------------------------------TLGTFAGVFSPVALSMFSALVFIRVGYIVGN 94
            .:|.                              ..||:.|||:...:::|..:||:|.|:||..
  Fly    57 AAGGHHASGANEIFAGEQGDKPWWRSNFFISQPVLFGTWDGVFTSCLINVFGVIVFLRSGWIVAQ 121

  Fly    95 AGLYVTLLQFLIAYGILLFTVASVCAISTNGAIEGGGVYFMISRTLGLEFGGSIGTLFFFANVVG 159
            ||:...:|.......|.|.:|.|...|.....:|.|||||:|:.|||..|||::|.|:.|...||
  Fly   122 AGILNAVLIIFCTVVIALVSVLSAIGICERCRVESGGVYFLIAHTLGSRFGGALGLLYCFGQAVG 186

  Fly   160 SAMAISGCTEGIMDNFGPRGHFVSGDSHLPDGDWWR---FLTSSMINTLQLLVCL--VGAALFAK 219
            .|:.:.|..|.:....|            .:|..|.   |.|::::    ||.|:  .|.....|
  Fly   187 CALNVMGFGESMAGLVG------------LEGSKWAIRGFATAAVL----LLGCINVAGVKWVIK 235

  Fly   220 TSVIILATVTVCLFATYFSFLFVGATNNTIPVPGDNILSNTTTFLDYTGLNATTLRDNLGSHYGR 284
            ...|:|    :.|..:...|: ||:.  |....|           .:.|..:....:||...|..
  Fly   236 LQFILL----MILLISALDFM-VGSF--TSEASG-----------GFNGWASGNFVENLWPKYDD 282

  Fly   285 DYTSNGKQVDFSTTFGVLFSGVTGIMAGANMSGELKNPSKSIPYGTLSAVAFTFVSYIILSFLMS 349
            .|:       :...|||.|..|||:::|.||||:|:.||..||.|||:|...:...|::....:.
  Fly   283 GYS-------WFRVFGVFFPTVTGVLSGINMSGDLRAPSTDIPNGTLAAFGTSTFLYLVFVLFLG 340

  Fly   350 CTTPYFTMQNNYLFLMPVNLWPPFTAIGILTATFSTSLSNLIGSSRILEALSKDQVFGSLLNFVI 414
            .|.....:..:|:..:.|:........||..::.|:.|..:.|:.|:|::::|:.|...:   .|
  Fly   341 ATCQRSFLYTDYMISVKVSAVHFLLLAGIYVSSMSSCLGAMYGTPRVLQSIAKESVIPGI---DI 402

  Fly   415 HGTWKGN---PIAAVAVSWCLVECILLIGSFNIIAQINSVLFMLSYLATNLACLGIELT 470
            .|..:|.   |:.|:|:...:....:::|..|.:|.|.::.|:|:|...:.|...:..|
  Fly   403 LGKGRGPNKVPLYAMAIVALVTVTFIIVGDINFLAPIVTMPFLLTYACIDYAYFALAQT 461

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10413	NP_001286048.1	2a30	22..932	CDD:273347	125/493 (25%)
CG10413	NP_001286048.1	SLC12	577..932	CDD:281515
CG12773	NP_001284773.1	2a30	88..>456	CDD:273347	112/411 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45467890
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11827
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940