Protein Alignment CG10413 and Slc12a7

DIOPT Version :10

• Sequence 1: NP_609887.1
• Gene: CG10413 / 35111
• FlyBaseID: FBgn0032689
• Length: 941
• Species: Drosophila melanogaster
• Sequence 2: XP_063144456.1
• Gene: Slc12a7 / 308069
• RGDID: 1359672
• Length: 1179
• Species: Rattus norvegicus
• Alignment Length: 983
• Identity: 256/983 - (26%)
• Similarity: 423/983 - (43%)
• Gaps: 203/983 - (20%)

  Fly    49 GYVEFGMQDPDRSGR-----TLGTFAGVFSPVALSMFSALVFIRVGYIVGNAGLYVTLLQFLIAY 108
            |.||. .:|.|...|     .:|||.||:.|...::...::|:|:.:|||.||:..:.|...:..
  Rat   130 GVVEH-EEDEDSRRREIKAPRMGTFIGVYLPCLQNILGVILFLRLTWIVGAAGVLESFLIVAMCC 193

  Fly   109 GILLFTVASVCAISTNGAIEGGGVYFMISRTLGLEFGGSIGTLFFFANVVGSAMAISGCTEGIMD 173
            ...:.|..|:.||:|||.:..||.|:||||:||.||||::|..|:.......||.|.|..|..:.
  Rat   194 TCTMLTAISMSAIATNGVVPAGGSYYMISRSLGPEFGGAVGLCFYLGTTFAGAMYILGTIEIFLT 258

  Fly   174 NFGPRGHFVSGDSHLPDGDWWRFLTSSMINTLQL----------LVCLVGAALFAKTSVIILATV 228
            ...|.......::  .||:     .::::|.:::          :|..||.....|.:::.||.|
  Rat   259 YISPSAAIFQAET--ADGE-----AAALLNNMRVYGSCALALMAVVVFVGVKYVNKLALVFLACV 316

  Fly   229 TVCLFATYFSFLFVGATNNTIPV--PGDNILSN----------------TTTFL----------- 264
            .:.:.|.|...:........|||  .|:..|:|                .||.|
  Rat   317 VLSILAIYAGVIKTAFAPPDIPVCLLGNRTLANRNFDTCAKMQVVSNGTVTTALWRLFCNGSSLG 381

  Fly   265 ----DY------------TGLNATTLRDNLGSHY------------------------GRDYTSN 289
                :|            .|:.:....|||.|.|                        |..|...
  Rat   382 ASCDEYFVQNNVTEIQGIPGVASGVFLDNLWSTYSDKGAFVEKKGVSSVPVSEESRPGGLPYVLT 446

  Fly   290 GKQVDFSTTFGVLFSGVTGIMAGANMSGELKNPSKSIPYGTLSAVAFTFVSYIILSFLMSCTTPY 354
            .....|:...|:.|..|||||||:|.||:||:..||||.||:.|:..|...|:....|.......
  Rat   447 DIMTYFTMLVGIYFPSVTGIMAGSNRSGDLKDAQKSIPTGTILAIVTTSFIYLSCIVLFGACIEG 511

  Fly   355 FTMQNNYLFLMPVNL------WP-PFT-AIGILTATFSTSLSNLIGSSRILEALSKD------QV 405
            ..:::.:...:..||      || |:. .||...:|....|.:|.|:.|:|:|:::|      ||
  Rat   512 VVLRDKFGEALQGNLVIGMLAWPSPWVIVIGSFFSTCGAGLQSLTGAPRLLQAIARDGIIPFLQV 576

  Fly   406 FGSLLNFVIHGTWKGNPIAAVAVSWCLVECILLIGSFNIIAQINSVLFMLSYLATNLACLGIELT 470
            ||       ||...|.|..|:.::..:.|..:||.|.:.:|.|.|:.|::.|:..||||....|.
  Rat   577 FG-------HGKANGEPTWALLLTALICETGILIASLDSVAPILSMFFLMCYMFVNLACAVQTLL 634

  Fly   471 GAPNFRPLFKFFTWHTCLVGLLGTLIMMFVINFIYASSCIIL--CLILVIALHLFSPATQAAQWG 533
            ..||:||.|||:.|....:|:...|.:||:.::.||...:::  |:...|.   :..|.:  :||
  Rat   635 RTPNWRPRFKFYHWTLSFLGMSLCLALMFICSWYYALFAMLIAGCIYKYIE---YRGAEK--EWG 694

  Fly   534 SISQALMFHQVRKYLLMLDPRKDHVKFWRPQILLLVSSPRSCC----PLVDFVNDLKK-SGLYII 593
            ...:.|..:..|..||.::....|.|.||||:|::::.....|    .|:.|.:.||. .||.|:
  Rat   695 DGIRGLSLNAARYALLRVEHGPPHTKNWRPQVLVMLNLDSEQCVKHPRLLSFTSQLKAGKGLTIV 759

  Fly   594 GHVKLGDF--KGIE--DAEDNQQWWSFLDHMRVKAFTEVTLSRSIREGVQHLIRLSGIGAMKPNT 654
            |.|..|.:  |.:|  .||:|.:  |.:...::|.|.::.:|.::|:|..|||:.:|:|.||.||
  Rat   760 GSVLEGTYLDKHVEAQRAEENIR--SLMSAEKMKGFCQLVVSSNLRDGASHLIQSAGLGGMKHNT 822

  Fly   655 IILGFYDSEAPRDFFQNGSSPYKTDDFNNGEIQNFPIRRDGDPKQFQIQEYVQILCDTLRMKKNL 719
            :::.:.::      ::...:|                        |..:.:|..:.||....:.|
  Rat   823 VLMAWPEA------WKQADNP------------------------FSWKNFVDTVRDTTAAHQAL 857

  Fly   720 CLCRNFQRLDKNFISMSKHVKYIDVWPINIFNPTSGDPFDMVSLFMMQLAVIMLAKWKHLRVRIF 784
            .:.:|.....:|....|.  ..||||.|    ...|....::...:.|..|     |:..|:|||
  Rat   858 LVAKNIDLFPQNQERFSD--GNIDVWWI----VHDGGMLMLLPFLLRQHKV-----WRKCRMRIF 911

  Fly   785 LCEANDERTVGTFDTQTPQMEIFSKMKLEQSLKELRITADIVEIQEWSRDTDFSRHARTLKQFTA 849
                    ||...|..:.||    |..|:..|..|||:|::..::....|.....:.:||
  Rat   912 --------TVAQVDDNSIQM----KKDLQMFLYHLRISAEVEVVEMVENDISAFTYEKTL----- 959

  Fly   850 QADNVVLEDDDEVGEETLNRSLLYMQRANQIIRERSDQTALSFIYLA---APPKLSAPDFAQRSA 911
                 ::|...::.:: :..|....:|..|:|.:|:  ||...:..|   |||   .||..|.:.
  Rat   960 -----MMEQRSQMLKQ-MQLSKNEREREAQLIHDRN--TASHTVATARTEAPP---TPDKVQMTW 1013

  Fly   912 SYMELLTE 919
            :..:|:.|
  Rat  1014 TKEKLIAE 1021

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10413	NP_609887.1	AA_permease_2	22..932	CDD:459263	256/983 (26%)
Slc12a7	XP_063144456.1	None