DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10413 and F10E7.9

DIOPT Version :9

Sequence 1:	NP_001286048.1	Gene:	CG10413 / 35111	FlyBaseID:	FBgn0032689	Length:	941	Species:	Drosophila melanogaster
Sequence 2:	NP_495469.2	Gene:	F10E7.9 / 174167	WormBaseID:	WBGene00017350	Length:	603	Species:	Caenorhabditis elegans

Alignment Length:	555	Identity:	133/555 - (23%)
Similarity:	239/555 - (43%)	Gaps:	115/555 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    66 GTFAGVFSPVALSMFSALVFIRVGYIVGNAGLYVTLLQFLIAYGILLFTVASVCAISTNGAIEGG 130
            ||:.|||:.|.:::|..:||:|:|:|||.||:..::|...|...:.|.||.|...|.....|:.|
Worm    48 GTWDGVFATVMVNIFGIIVFLRLGWIVGTAGVANSILLLGICTSLALITVFSAIGIVERCQIKSG 112

  Fly   131 GVYFMISRTLGLEFGGSIGTLFFFANVVGSAMAISGCTEGIMDNFGPRGHFVSGDSHLPDGDWWR 195
            |:||::|..||.:.||:||.::.|...|.:.:...|..|.:       .|....:|.:
Worm   113 GIYFLVSHVLGHQIGGAIGIIYAFGQAVATGLVAVGFGESV-------AHLFESESKI------- 163

  Fly   196 FLTSSMINTLQLLVCL--VGAALFAKTSVIILATVTVCLFATYFSFLFVGATNNTIPVPGDNILS 258
            .:....|.||.:|..:  .|.....:..:::|  :|:.|..|.|.|   ||..::.|..|
Worm   164 MIKGIAILTLMVLTAVNTAGVTWVVRLQIVLL--LTIALAVTDFIF---GALFSSEPESG----- 218

  Fly   259 NTTTFLDYTGLNATTLRDNLGSHY---GRDYTSNGKQV---DFSTTFGVLFSGVTGIMAGANMSG 317
                   ....::..:|.|..|||   ........:|:   .|.|.|||.|:...|::||.||||
Worm   219 -------VFRFSSERIRVNADSHYEAVNCSIIGIPRQIPEQSFFTVFGVFFANFLGVLAGVNMSG 276

  Fly   318 ELKNPSKSIPYGTLSAVAFT----FVSYIILSFLMSCTTPYFTMQNNYLFLM-------PVNLWP 371
            :||:|.||||.|.||||..:    |:..:||..:           .:.:||:       .|.|..
Worm   277 DLKDPHKSIPLGELSAVGVSSTICFIFIMILGGV-----------GDRMFLLCDVMISEKVALTG 330

  Fly   372 PFTAIGILTATFSTSLSNLIGSSRILEALSKDQVFGSLLNFVIHGTW-KGNPIAAVAVSWCLVEC 435
            ....:|:...:.|:::.:|:|:.|:|:.::::.:. ..||.:..|.. ..||:.|..:...:...
Worm   331 IVFLVGLYVCSLSSTVGSLLGTPRVLQGIAEEGII-PCLNVLARGVGPNDNPVLAGYLLMGVASL 394

  Fly   436 ILLIGSFNIIAQINSVLFMLSYLATNLACLGIELT-----------------GAPN-FRPLFKFF 482
            .:|:|..|.:|.::::.|:::|...|.:.:.:.::                 |:.| ...|.:.|
Worm   395 FVLLGDLNQLAILSTMPFLITYAYVNYSYVSLAMSYDLATVQHADEVETVGYGSTNKMNDLNELF 459

  Fly   483 -----------------------TWHT-------CLVGLLGTLIMMFVINFIYASSCIILCLILV 517
                                   ||::       ..:|.|..|.::.:|:|.:|    :...:.:
Worm   460 PERRDVNITSTEETETGIISQEATWYSMFSNRYVSFLGFLVNLAILLLIHFWFA----VAHFVAL 520

  Fly   518 IALHLFSPATQAAQWGSISQALMFHQVRKYLLMLD 552
            |||:.:...........||...:.|..:.....||
Worm   521 IALYWYIGRVCPTCGPGISTFSLCHMFKTVFSSLD 555

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10413	NP_001286048.1	2a30	22..932	CDD:273347	133/555 (24%)
CG10413	NP_001286048.1	SLC12	577..932	CDD:281515
F10E7.9	NP_495469.2	2a30	47..>557	CDD:273347	133/555 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910