Protein Alignment CG10413 and slc12a3

DIOPT Version :9

• Sequence 1: NP_001286048.1
• Gene: CG10413 / 35111
• FlyBaseID: FBgn0032689
• Length: 941
• Species: Drosophila melanogaster
• Sequence 2: XP_002937217.2
• Gene: slc12a3 / 100494755
• XenbaseID: XB-GENE-866805
• Length: 1030
• Species: Xenopus tropicalis
• Alignment Length: 1031
• Identity: 257/1031 - (24%)
• Similarity: 419/1031 - (40%)
• Gaps: 258/1031 - (25%)

  Fly    39 DRPHTPQDGDGYVEFGMQDPDRSGRTLGTFAGVFSPVALSMFSALVFIRVGYIVGNAGLYVTLLQ 103
            |..:|.:..||..|...|.|.......|...||.....|:::..::::|:.:|...||:.:|.|.
 Frog   110 DYDNTVEPPDGEAENTEQKPAGEPVRFGWIKGVMIRCMLNIWGVILYLRLPWITAQAGIALTWLI 174

  Fly   104 FLIAYGILLFTVASVCAISTNGAIEGGGVYFMISRTLGLEFGGSIGTLFFFANVVGSAMAISGCT 168
            ..::..:...|..|:.||||||.::.||.||:|||:||.|.|||||.:|.|||.|..||...|..
 Frog   175 IFMSVTVTSITGLSISAISTNGKVKSGGTYFLISRSLGPELGGSIGLIFAFANAVAVAMHTVGFA 239

  Fly   169 EGIMDNFGPRGHFVSGDSHLPDGDWWRFLTSSMINTLQLL-----VCLVGAALF-----AKTSVI 223
            |.:.|..  |.:    ||.:.|          .||.::::     :.|:|.:|.     ||..::
 Frog   240 ETVRDLL--RDY----DSTIVD----------PINDIRIIGIITVIVLLGISLAGMEWEAKAQIL 288

  Fly   224 ILATVTVCLFATYFSFLFVGATNNTIPVPGDNILSNTTTFLDYTGLNATTLRDNLGSHYGRDYTS 288
            ....:.:. ||.|.....:.||..          .....|..|   .|....:|....:
 Frog   289 FFIVIMIS-FANYLVGTVIPATEE----------KQAKGFFSY---RADIFAENFVPKW------ 333

  Fly   289 NGKQVDFSTTFGVLFSGVTGIMAGANMSGELKNPSKSIPYGTLSAVAFTFVSYIILSFLM-SCT- 351
            .|:...|...|.:.|...|||:||||:||:||:|:.:||.|||.::.:|.|||:::|..: ||.
 Frog   334 RGQDGSFFGMFSIFFPSATGILAGANISGDLKDPTVAIPKGTLMSIFWTTVSYLVISATIGSCVV 398

  Fly   352 -----------------------------TPYFTMQ-------NNYLFLMPVNLWPPFTAIGILT 380
                                         |...|.|       |.|..:..|:.:.|....||..
 Frog   399 RDASGSLNDTITDGGLNCVGLACGYGWNFTDCATKQNCKYGLINQYQSMSMVSGFAPLVTAGIFG 463

  Fly   381 ATFSTSLSNLIGSSRILEALSKDQVFGSLLNFVIHGTWKGN-PIAAVAVSWCLVECILLIGSFNI 444
            ||.|::|:.|:.:.::.:.|.||.:: .|:.|...|..|.| ||....:::.:....:|||..|.
 Frog   464 ATLSSALACLVSAPKVFQCLCKDNLY-PLIGFFGKGYGKNNEPIRGYLLTFLIASAFILIGELNT 527

  Fly   445 IAQINSVLFMLSYLATNLACLGIELTGAPNFRPLFKFFTWHTCLVGLLGTLIMMFVINFIYASSC 509
            ||.|.|..|:.||...|.:|....:|.:|.:||.||:::....|.|.:.::::||::.:   .|.
 Frog   528 IAPIISNFFLCSYALINFSCFHASITNSPGWRPSFKYYSKWASLFGAVASVVIMFLLAW---ESA 589

  Fly   510 IILCLILVIALHLFSPATQAAQWGSISQALMFHQVRKYLLMLDPRKDHVKFWRPQILLLVSSPRS 574
            :|...|::..|.........|.|||..||..::....|.:.|:..::|:|.:|||.|:|...|..
 Frog   590 LIAIGIVIFLLGYVLYKKPEANWGSSVQAGSYNMALSYCVGLNQVEEHIKNFRPQCLVLTGPPNF 654

  Fly   575 CCPLVDFVNDL-KKSGLYIIGHVKLGDFK-GIED--AEDNQQWWSFLDHMRVKAFTEVTLSRSIR 635
            ...|||||... ||..|.|.|:|.:|..| .:::  .|.:.:|   |:..::|||....::..:|
 Frog   655 RPALVDFVGTFTKKQSLMICGNVIIGPRKQKLQEISPEGHIKW---LNKRKIKAFYTGLIADDLR 716

  Fly   636 EGVQHLIRLSGIGAMKPNTIILGF---YDSEAPRDFFQNGSSPYKTDDFNNGEIQNFPIRRDGDP 697
            .|.|.||:.:|:|.|:||.:::||   :.:..||
 Frog   717 SGTQMLIQAAGLGHMRPNVLVMGFKKNWSTSHPR------------------------------- 750

  Fly   698 KQFQIQEYVQILCDTLRMKKNLCLCR-----NFQR------------------------------ 727
               ..:.||.||.|.|..|..|||.|     |..|
 Frog   751 ---STENYVGILHDALDFKCGLCLLRMKEGINISRVMQAHINPVYEQTEEPKLKDGGENGASCSA 812

  Fly   728 ---LDKNFISMSKHV----------KYIDVWPINIFNPTSGDPFDMVSLFMMQLAVIMLAK-WKH 778
               ||...:::.:..          |.||::.:          ||...|.::...::...| |:.
 Frog   813 QSTLDPEAVTVEQQASTIFQIKQDKKTIDIYWL----------FDDGGLTLLIPYLLSRKKRWQK 867

  Fly   779 LRVRIFL----------CEANDERTVGTFDTQTPQMEIFSKMKLEQSLKELRITADIVEIQEWSR 833
            .::|:|:          |:|              .:.:.||.::  ...|:.:..||.:
 Frog   868 AKIRVFVGGQINRMDEECKA--------------MISLLSKFRI--GFHEVHVLPDINQ------ 910

  Fly   834 DTDFSRHARTLKQFTAQADNVVLED--------------------DDEVGEETLNRSLLYMQ-RA 877
                ......:|:|.......:|.|                    |:|:.:   ||:....| |.
 Frog   911 ----KPRPEHIKRFEDLIAPYMLNDGFKDELTVNEMRRDCPWKISDEEIKK---NRAKSLRQIRL 968

  Fly   878 NQIIRERSDQTALSFIYLAAPPKLSAPDFAQRSASYMELLTELTADL-PPTILVHG 932
            |:::.:.|....|..|.:....|...|     |..||..|..|:.|| ||.:|..|
 Frog   969 NEVLLDYSRDAGLIVITMPIARKGKCP-----STLYMAWLETLSQDLRPPVLLTRG 1019

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10413	NP_001286048.1	2a30	22..932	CDD:273347	256/1029 (25%)
		SLC12	577..932	CDD:281515	91/442 (21%)
slc12a3	XP_002937217.2	2a30	64..1029	CDD:273347	257/1031 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910