Protein Alignment CG10413 and slc12a4

DIOPT Version :10

• Sequence 1: NP_609887.1
• Gene: CG10413 / 35111
• FlyBaseID: FBgn0032689
• Length: 941
• Species: Drosophila melanogaster
• Sequence 2: XP_002942716.1
• Gene: slc12a4 / 100493471
• XenbaseID: XB-GENE-1014107
• Length: 1090
• Species: Xenopus tropicalis
• Alignment Length: 1063
• Identity: 282/1063 - (26%)
• Similarity: 429/1063 - (40%)
• Gaps: 283/1063 - (26%)

  Fly    65 LGTFAGVFSPVALSMFSALVFIRVGYIVGNAGLYVTLLQFLIAYGILLFTVASVCAISTNGAIEG 129
            :||..||:.|...::...::|:|:.:|||..|:..|||..||.....|.|..|:.||:|||.:..
 Frog   122 MGTVMGVYLPCMQNILGVILFLRLTWIVGTGGVLQTLLITLICCCCTLLTAISMSAIATNGVVPA 186

  Fly   130 GGVYFMISRTLGLEFGGSIGTLFFFANVVGSAMAISGCTEGIMDNFGPRGH-FVSGDSHLPDGDW 193
            ||.||||||:||.||||::|..|:.......||.|.|..|.::....|... |.|.::|..
 Frog   187 GGSYFMISRSLGPEFGGAVGLCFYLGTTFAGAMYILGAIEILLMYIVPEAAIFHSPNTHED---- 247

  Fly   194 WRFLTSSMIN----------TLQLLVCLVGAALFAKTSVIILATVTVCLFATY------------ 236
                :|:.:|          ||..::..||.....|.:.:.||.|.:.:.:.|
 Frog   248 ----SSAKLNNMRVYGTVFLTLMAIIVFVGVKYVNKFASLFLACVIISILSIYAGSIKSIFDPPV 308

  Fly   237 FSFLFVGATNNTI----------PVPGDNILSNTTTFLDYTGL---------------NAT---- 272
            |....:|  |.|:          .:..||:...||.:..:.|.               |.|
 Frog   309 FPICMLG--NRTLSRDRFEICAKTIILDNVTKPTTLWEQFCGSSNFSTSSCDQYFLKNNVTEIAG 371

  Fly   273 -------TLRDNLGSHY-------GRDYTSNGKQV------------DFSTTF----GVLFSGVT 307
                   .|:|||.|:|       .:...|:..::            |.|.||    |:.|..||
 Frog   372 IPGAASGILKDNLWSNYLQKGEILEKSQLSSVDELGSKSNLHLYVLTDISATFTVLVGIFFPSVT 436

  Fly   308 GIMAGANMSGELKNPSKSIPYGTLSAVAFTFVSYIILSFLMSCTTPYFTMQNNYLFLMPVNL--- 369
            |||||:|.||:|::..||||.||:.|:..|...|.....|.........:::.|...:..||
 Frog   437 GIMAGSNRSGDLRDAQKSIPVGTILAIITTSFIYFSTVVLFGACIEGVVLRDKYGDAVNKNLVVG 501

  Fly   370 ---WP-PFT-AIGILTATFSTSLSNLIGSSRILEALSKD------QVFGSLLNFVIHGTWKGNPI 423
               || |:. .||...:|....|.:|.|:.|:|:|::.|      :|||       .|...|.|.
 Frog   502 TLSWPSPWVIVIGSFFSTCGAGLQSLTGAPRLLQAIANDNIIPFLRVFG-------QGKVNGEPT 559

  Fly   424 AAVAVSWCLVECILLIGSFNIIAQINSVLFMLSYLATNLACLGIELTGAPNFRPLFKFFTWHTCL 488
            .|:.::..:.|..:||.|.:::|.|.|:.|::.||..||||....|...||:||.||::.|....
 Frog   560 WALLLTAFIAELGILIASLDMVAPILSMFFLMCYLFVNLACAVQTLLRTPNWRPRFKYYHWALSF 624

  Fly   489 VGLLGTLIMMFVINFIYASSCIILCLILVIALHLFSPATQAAQWGSISQALMFHQVRKYLLMLDP 553
            .|:...|.:|||.::.||   :|..||..:............:||...:.|.....|..||.|:.
 Frog   625 FGMSICLALMFVCSWYYA---LIAMLIAGMIYKYIEYQGAEKEWGDGIRGLSLSAARYALLRLEE 686

  Fly   554 RKDHVKFWRPQILLL--------VSSPRSCCPLVDFVNDLKK-SGLYIIGHVKLGDF----KGIE 605
            ...|.|.||||:|:|        |..||    |:.|.:.||. .||.|||....|:|    ..::
 Frog   687 GPPHTKNWRPQLLVLLKLDEDLHVKYPR----LLTFSSQLKAGKGLTIIGTTLQGNFLESYGEVQ 747

  Fly   606 DAEDNQQWWSFLDHMRVKAFTEVTLSRSIREGVQHLIRLSGIGAMKPNTIILGFYDSEAPRDFFQ 670
            .||  |...:.::..:||.|::|.:|..:.:|:.|||:..|:|.||.||::||:
 Frog   748 AAE--QTIKNMMEIEKVKGFSQVVVSSEVCDGISHLIQSCGLGGMKHNTVLLGW----------- 799

  Fly   671 NGSSPYKTDDFNNGEIQNFPIRRDGDPKQFQIQEYVQILCDTLRMKKNLCLCRNFQRL----DKN 731
                ||..             |:..||:.:      :...|.:|       |....||    .||
 Frog   800 ----PYGW-------------RQSEDPRSW------KTFIDAVR-------CTTAARLALMVPKN 834

  Fly   732 FISM--SKHVKY----IDVWPINIFNPTSGDPFDMVSLFMMQLAVIMLAKWKHLRVRIFLCEAND 790
             :|.  |.|.:|    ||||.|    ...|....::...:.|..|     ||..::|||
 Frog   835 -VSFYPSNHERYLEGNIDVWWI----VHDGGMLMLLPFLLKQHKV-----WKKCKMRIF------ 883

  Fly   791 ERTVGTFDTQTPQMEIFSKMKLEQSLKELRITADIVEIQEWSRDTDFSRHARTL----------- 844
              ||...|..:.||    |..|...|..||:.|::..::..:.|.....:.|||
 Frog   884 --TVAQLDDNSIQM----KKDLATFLYHLRLEAEVEVVEMHNSDISAYTYERTLMMEQRSQMLRQ 942

  Fly   845 -----------KQFTAQADNVV------LEDDDEVGE------------------------ETLN 868
                       .|.....::::      .:::||..|                        ||::
 Frog   943 MRLTKTERDREAQLVKDRNSIIPVESYYSDEEDEEPELELAKIHMTWTKDKYNAQWKNRNNETMH 1007

  Fly   869 --------------RSLLYMQRANQIIRERSDQTALSFIYLAAPPKLSAPDFAQRSASYMELLTE 919
                          |.:....:.|::|..||....|..:.:..|||.:..|     .:|||.|..
 Frog  1008 FRELADIKPDQSNVRRMHTAVKLNEVIVTRSHDAKLVLLNMPGPPKNTDGD-----ENYMEFLEV 1067

  Fly   920 LTADLPPTILVHG----VSTVTS 938
            ||..|...:||.|    |.|:.|
 Frog  1068 LTEGLERVLLVRGGGREVITIYS 1090

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10413	NP_609887.1	AA_permease_2	22..932	CDD:459263	278/1051 (26%)
slc12a4	XP_002942716.1	2a30	49..1090	CDD:273347	281/1061 (26%)